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On this replay preview of Brave New World, Evgeny Lebedev is joined by Dr John Krystal — Professor of Neuroscience at the Yale School of Medicine — to explore how ketamine could transform the treatment of mental health disorders.They discuss what ketamine is, how it works, and why it’s being hailed as a breakthrough in tackling the global mental health crisis.Listen to the full conversation on the Brave New World podcast here.

On this replay preview of Brave New World, Evgeny Lebedev is in conversation with Dr Peter Attia — a leading physician, longevity expert, and bestselling author.Together they explore Medicine 3.0 — Peter’s blueprint for extending both lifespan and healthspan — and why emotional wellbeing is just as vital as physical health.“It doesn’t matter how healthy you are,” Peter says, “if the most important relationships in your life are not happy.”Listen to the full conversation on the Brave New World podcast here.

On this replay preview of Brave New World, Evgeny Lebedev is joined by Dr Aubrey de Grey — a pioneering biomedical gerontologist and co-founder of the SENS Research Foundation.Known for his radical views on ageing, Dr de Grey believes we can and should treat ageing as a medical condition, not an inevitability.In this fascinating conversation, Evgeny and Aubrey explore everything from the ethics of life extension and the science behind reversing cellular damage, to how society might change if ageing becomes optional.Listen to the full conversation on the Brave New World podcast here.

A flotilla of Indigenous leaders have made a symbolic journey from the glaciers of the Andes to Belém, Brazil in time for the COP30 climate summit.Their mission: to demand a greater role in climate talks and protections for their territories, as extraction industries and climate change press ever deeper into Indigenous lands.Super Typhoon Fung-wong has weakened after battering the Philippines this weekend.Wind speeds of around 115 mph dropped to between 80 and 100 mph as the storm moved northeast towards Taiwan.An international team of scientists has achieved a world-first, creating plasma 'fireballs' to discover how powerful jets from distant black holes stay stable.Pablo Bilbau, a postdoctoral research fellow at the University of Oxford, explained what they’ve been doing and whyAlso in this episode:China has partially lifted export controls on key computer chips used in car productionA new national forest has been confirmed for the Oxford-Cambridge corridorScientists say camels and llamas could help unlock new treatments for brain disorders

Elon Musk, already the world’s richest man, has had a record-breaking pay deal approved — one that could be worth nearly $1 trillion.At Tesla’s annual meeting in Texas, 75% of shareholders backed the move, giving Musk what’s believed to be the biggest compensation package in corporate history.But over the next decade, will he hit the huge goals needed to earn it?Sir Keir Starmer has told COP30 that the UK is “all in” on net zero.Speaking in Belem, the gateway to the Brazilian Amazon, the Prime Minister said clean energy is key to jobs, growth, and climate security.It comes as the UN warns 2025 is set to be the second or third hottest year on record, after an “unprecedented streak” of global heat.The University of Cambridge is offering a new, minimally invasive enzyme injection to treat a severe spinal disease in dogs — the first and only treatment of its kind in the UK.The injection has been said to have an exceptional success rate.It targets intervertebral disc disease, which affects around a quarter of dachshunds.We’ll hear from Professor Paul Freeman at Cambridge’s Veterinary School, who co-developed the treatment with colleagues at Texas A&M University.Also in this episode:The much-awaited GTA 6 has been delayed again, now expected in November 2026.Scientists warn that a common diabetes drug may reduce the benefits of exercise.Google announces its biggest-ever carbon removal deal, funding restoration of the Amazon rainforest through carbon credits.

Ever heard of “vibe coding”? It's been named Word of the Year by Collins Dictionary, but what does it mean?You can thank OpenAI's co-founder Andrej Karpathy, who came up with the phrase.The World Weather Attribution has released new data revealing that climate change significantly amplified Hurricane Melissa’s destructive winds and rainfall.We speak to the rapid study's co-author, climate scientist Theodore Keeping, from the World Weather Attribution team at Imperial College London.Three Chinese astronauts are stuck in space for longer than expected, after an unidentified object hits the return spacecraft.Also in this episode:UK energy supplier Tomato Energy has collapsedPrince William honours young environmentalists at Earthshot PrizeThe newly described species of toads that give birth to fully formed toadletsAI chatbots "suffer from brainrot" too

Marks & Spencer’s revealed the impact of a massive cyber attack earlier this year. The retailer says profits were hit hard when hackers took them offline at Easter, knocking out online sales and leaving shelves bare for weeks.Elsewhere, scientists in London are looking at whether wireless power could be used to keep lunar rovers running in space. The collaboration between Imperial College London and MSA Space is being funded by the UK Space Agency.Suze Cooper speaks to Professor of Electrical Energy Conversion at Imperial, Paul Mitcheson, about what it could mean for future space exploration.Also in this episode…Plans to block scam mobile calls from abroad within a yearIs Government red tape causing UK science and tech to ‘bleed out’?Scientists warn geoengineering could trigger droughts and hurricanesSky Live to be discontinued less than three years after launchWhatsApp officially arrives for Apple Watch wearersAn extra reason to look to the skies this bonfire night

OpenAI has signed a $38 billion (£29 billion) deal with Amazon.The seven-year partnership gives OpenAI access to Amazon Web Services. It’s the latest in a string of partnerships necessary to ensure what OpenAI CEO Sam Altman describes as the ‘massive, reliable compute’ needed to scale up AI.Elsewhere, UK scientists have developed a gel that encourages teeth to regrow their own enamel - something long thought impossible. We speak to Professor Alvaro Mata, Chair in Biomedical Engineering & Biomaterials at the University of Nottingham, about how it works and why it’s a breakthrough for oral healthcare.Also in this episode…Victims of ‘silent scandal’ pregnancy drug call for UK inquiryStudy shows walking 5,000 steps a day could slow Alzheimer’s-linked brain declineAmazon rolls out UK’s largest fleet of electric lorriesAre video game developers breaking the law by ‘switching off’ games people have purchased?The campaign calling on parents to get their kids moving this winterCan chimpanzees make rational decisions?

Water companies are being urged to clean up potentially harmful ‘forever chemicals’ in drinking water.High levels of per and polyfluoroalkyl substances have been discovered in UK water sources and while industry body Water UK says it’s still safe to drink - they are calling for a ban on the chemicals to avoid future problems.Also in this episode, The Bionic Awards are coming to London. Entries are now open for the inaugural event to be held in Shoreditch next year. We speak to founder of the awards and London Standard tech editor Alex Pell along with AI filmmaker Diane Laidlaw of Afro Futcha, about the importance of recognising AI creativity.Plus…A new £1.9million study will look at whether AI can help doctors make better decisions around how to treat prostate cancerNew research shows skipping breakfast might leave you feeling hungry but won’t impact your thinking skillsThe Microsoft glitch that’s waited 10 years for a fixA new sustainable tub for Cadbury’s Heroes and a change to the chocolate line-up