Solving the Puzzle with Dr. Datis Kharrazian

In this episode, Dr. Steven Sandberg-Lewis reveals three commonly overlooked root causes of chronic digestive disorders: traumatic brain injury, hypermobility syndrome, and diagnosis momentum. Drawing from 46 years of clinical practice, Dr. Sandberg-Lewis explains why conventional approaches miss these critical factors and how practitioners can identify them through simple screening methods.Enroll in the complete master class: How to Think Like a Functional Gastroenterologist with Dr. Steven Sandberg-Lewis (6 hours) at pages.kharrazianinstitute.com/ssl-gastro⁠ to access over 45 years of refined clinical protocols and systematic approaches.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Invisible Impacts of Brain Injury03:17 Traumatic Brain Injury & GI Effects06:49 Interactive Metronome for Brain Timing12:23 Hypermobility, GI Issues, and Celiac14:30 Diagnostic Bias and Gluten Testing17:07 "Functional Medicine & Health Resources"

In this episode, Dr. Kharrazian is joined by renowned physician Dr. Joseph Pizzorno, a pioneering voice in environmental medicine and toxicology. Together, they dive into the hidden world of environmental toxins—discussing the staggering number of chemicals we're exposed to every day, why testing for toxins can be more complex than most realize, and which common exposures may be silently sabotaging our health.Dr. Pizzorno reveals the challenges in accurately measuring toxic load, the wide differences in our bodies’ abilities to detoxify, and why focusing on exposure and biological damage is often more useful than hunting for specific chemicals in the blood or urine. You'll learn about practical strategies for identifying and reducing toxin exposure, the synergistic effects of multiple chemicals, and simple steps you can take to support your body’s natural defenses.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Assessing Exposure and Detox Challenges03:37 "Assessing Synergistic Environmental Toxins"07:09 "Toxic Load vs. Disease Correlation"11:24 Tea Habits and Water Concentration16:24 Chemical Impact on Neurological Health17:48 Persistent Human-Made Molecules23:20 Bisphenols Lowering Children's IQ26:18 Chemical Food Sources & Glyphosate Exposure28:26 Cerrillini's Impact on Glyphosate Regulation32:50 "Assessing Kidney Toxicity via EGFR"36:44 "Enhancing Body Detoxification"37:42 "Detox Strategy: Sweat and Monitor"

In today’s episode, Dr. Christy Sutton breaks down the crucial markers to monitor for iron overload, from classic liver enzymes and iron panels to the often-overlooked cardiovascular and autoimmune risk factors that can clue you into complications before they become serious. You’ll learn about ancillary labs to watch for side effects in the liver, kidneys, brain, hormones, cardiovascular system, and more. Dr. Sutton unpacks the practical nuances of interpreting test results, why “mildly elevated” liver enzymes should never be dismissed, and how overlapping factors like copper, magnesium, and vitamin deficiencies can shape both diagnosis and management. Join Dr. Christy Sutton's 6-hour Kharrazian Institute Master Class on Iron Overload & Undiagnosed Anemias and learn the protocols 90% of practitioners miss.Enroll: pages.kharrazianinstitute.com/sutton-anemiaFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Hemochromatosis Patient Lab Monitoring04:45 Glutathione Testing and Liver Health06:35 Type 1 Diabetes and Celiac Link12:24 Hemochromatosis and Cardiovascular Risk16:29 Copper and Ceruloplasmin Testing Insights19:49 Copper, Iron, Zinc: Balancing Act24:09 "Solving The Puzzle" Podcast Promo

Anemia affects millions but is often misunderstood or oversimplified. Anemia isn’t just about having low iron. It means you don’t have enough healthy red blood cells or hemoglobin to get vital oxygen to your tissues, organs, and brain. Host Chrissy Sutton breaks down the many different forms of anemia, from iron-deficiency to anemia of inflammation, and even discusses why you can actually have too much iron and still be anemic.We’ll explore how to spot anemia not just with lab work, but by recognizing physical signs like paleness, fatigue, brittle nails, and even changes in your tongue and the whites of your eyes. Dr. Sutton highlights why anemia is more than just feeling tired—it’s tied to everything from exercise intolerance and heart palpitations to developmental delays in children and increased risk for disorders like ADHD.This episode also unpacks the confusing overlap between high ferritin from inflammation versus hemochromatosis, goes in-depth on the impact of pregnancy and menstruation on iron levels, and shares actionable tips for both clinicians and patients. To learn more, enroll in the Master Class “Iron Overload and Undiagnosed Anemias” at https://pages.kharrazianinstitute.com/sutton-anemiaFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Anemia and Heart Strain Connection10:13 Low Iron Risks in Pregnancy11:40 Early Pregnancy Iron Supplementation18:14 Acid Reducers Impact Iron Levels26:50 Pregnancy: Nutrient Absorption Challenges31:43 "Decoding Iron Deficiency Causes"34:08 Iron Deficiency Anemia Symptoms40:51 Vitamin A Deficiency Risk Factors47:24 "Copper's Role in Iron Regulation"53:34 Diagnosing Hemolytic Anemia54:26 Managing Aplastic Anemia Basics01:01:52 Lead Cabinet Toxicity Solved01:06:09 Ferritin Management Without Blood Removal01:11:14 Digestive Challenges of Low Stomach Acid

In this episode, Dr. Kharrazian dives into childhood developmental disorders, with a special focus on dyslexia and processing challenges. Learn why children struggle with reading, writing, or social interaction and how sensory and motor coordination issues are linked to brain development.The conversation breaks down the different types of developmental disorders, from learning and sensory processing to motor skills, psychological health, and communication abilities. Dr. Kharrazian will clarify what dyslexia really is and explore its genetic roots, signs, symptoms, and why early diagnosis is critical. You’ll also hear insights on sensory processing disorders, motor tics, behavioral challenges, and how functional medicine can support children—and adults—facing these challenges by optimizing brain health and development. To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Identifying Learning Disorder Pathways05:15 Dyslexia Awareness and Diagnosis Progress15:37 "Dyslexia-Induced Cognitive Fatigue"19:40 Early Dyslexia Impact on Children25:35 Dyslexia: Genetics and Coping Strategies30:01 Dyslexia Screening: Nine Yes Indicators33:17 Supporting Dyslexia: Diagnosis and Brain Health37:23 Factors Impacting Brain Development46:34 Neurorehab: Develop Weak Brain Areas48:17 Sensory and Motor Disorders in Autism54:02 Frontostriatal Pathway and Tics01:00:47 "Understanding PANDAS/PANS in Children"01:08:19 Comprehensive Child Development Disorder Checklist01:09:25 "Pediatric Functional Medicine Overview"01:14:30 Functional Medicine & Nutrition Education

In this episode, Dr. Kharrazian dives into the rising rates and complexities of childhood developmental disorders, such as autism, ADHD, dyslexia, and sensory processing issues, and discusses why so many parents and even healthcare professionals feel overwhelmed or unsupported when it comes to helping these children thrive.Whether you’re a healthcare practitioner, parent, or someone interested in the foundations of healthy brain development, this conversation will give you an understanding of childhood developmental challenges and actionable tools to make a difference. To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Muscle Mass Essential for Longevity"03:05 Sarcopenia Significantly Increases Mortality Risk08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise10:56 Gut-Muscle Axis: Impact on Fitness13:09 Gut-Muscle Connection: Sarcopenia Insights17:33 Muscle Metabolism and Protein Sufficiency20:02 Protein Intake Crucial for Muscle Maintenance25:30 Muscle Issues: Causes and Solutions27:26 Creatine: Muscle Boost and Benefits32:19 Accelerated Muscle Aging Process35:52 Improving Muscle Metabolism with Autophagy38:58 Statins Linked to Muscle Dysfunction40:00 Statin Impact on Muscle Health43:08 Trigger Points and Myofascial Pain48:17 Myofascial Syndromes and Muscle Dysfunction52:52 Functional Medicine Training and Resources

In this episode, Dr. Datis Kharrazian explains what happens to our muscles as we age and why maintaining muscle mass is crucial for mobility, bone density, cognition, metabolic and immune health, and recovery from chronic illness. You’ll hear actionable insights about sarcopenia (age-related muscle loss), the muscle-gut connection, the power of myokines, and how hormones, nutrition, and strategic exercise can make a life-or-death difference.You’ll hear evidence-based guidance on protein intake, key nutrients, common causes of dysfunctional muscle metabolism, and how to identify and address issues like statin-induced myopathy and abnormal muscle tone.To dive deeper, enroll in the Kharrazian Institute’s Degenerative Joint, Muscle, and Bone Conditions Course.Sign up here: https://pages.kharrazianinstitute.com/ki-bone-jointFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Muscle Mass Essential for Longevity"03:05 Sarcopenia Significantly Increases Mortality Risk08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise10:56 Gut-Muscle Axis: Impact on Fitness13:09 Gut-Muscle Connection: Sarcopenia Insights17:33 Muscle Metabolism and Protein Sufficiency20:02 Protein Intake Crucial for Muscle Maintenance25:30 Muscle Issues: Causes and Solutions27:26 Creatine: Muscle Boost and Benefits32:19 Accelerated Muscle Aging Process35:52 Improving Muscle Metabolism with Autophagy38:58 Statins Linked to Muscle Dysfunction40:00 Statin Impact on Muscle Health43:08 Trigger Points and Myofascial Pain48:17 Myofascial Syndromes and Muscle Dysfunction52:52 Functional Medicine Training and Resources

In this episode, you’ll learn how movement directly influences your metabolism, immune system, brain function, and even the diversity of your gut microbiome. Dr. Kharrazian explains the critical role of messenger proteins released during physical activity, why maintaining muscle mass and bone density is key to longevity, and how inflammation can undermine your body’s ability to recover.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Introduction to the Podcast00:30 How Physical Movement Impacts Health01:54 Bone Volume, Osteopenia, and Health Consequences02:56 Toxic Chemicals, Bone Loss, and Aging03:50 Muscle Mass, Sarcopenia, and Mortality04:38 Movement, Depression, and Brain Chemistry05:15 Movement, Myokines, and Immune Function05:59 Microbiome Diversity, Gut Health, and Inactivity06:32 Overtraining Syndrome and its Red Flags07:11 Exercise, Mitochondrial Health, and Chronic Disease07:49 Movement & Brain Health: Repair, Mood, and Cognitive Disorders08:25 Sedentary Lifestyle in Children & Sarcopenia Risks09:45 Medical Management of Osteoporosis and Arthritis10:55 Inflammation, Muscular and Skeletal Degeneration12:16 Body Fat, Skinny Fat, and Inflammation12:46 Insulin Surges and Systemic Inflammation13:31 Microbiome, Leaky Gut, and Chronic Inflammatory Disease16:04 Food, Environmental Toxins, and Inflammation18:09 Protein Intake and Recovery from Chronic Disease19:12 Sleep, Sleep Apnea, and Bone Health19:57 Regenerative Medicine Therapies21:34 Conclusion and Podcast Resources

In this episode, we dive into the environmental and lifestyle factors that impact autoimmunity. From evaluating case reviews to understanding the significance of relationships, stress, and sleep, we explore how these elements shape autoimmune diseases. Discover how proper lifestyle medicine is crucial, and why it’s more than just about supplements. Learn about sleep disorders, chemical exposures, and the role of circadian rhythms in modulating the immune system. For more details, visit drknews.com.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Patient Screening and Case Review Process07:55 Sleep's Impact on Immune Function11:27 Rheumatoid Arthritis: Sleep's Vital Role16:15 Stress, Autoimmunity, and IL-17 Dynamics22:13 Exercise & Autoimmunity: Personalized Approach26:57 Chemical Bio-Transformation: Can vs. Can't31:17 Chemical Sensitivity and Immune Response37:45 BPA Study on Autoimmunity Impact44:16 "Identifying Active Heavy Metal Exposure"50:48 Chemical & Immune Tolerance Issues54:42 Avoiding Challenge Tests: Prioritize Immune Reactivity01:01:47 Optimizing Liver Detox and Nutrition01:06:54 Glutathione Protocol for Heavy Metals01:11:03 Glutathione Inhalation for Lung Health01:14:38 Dr. Kharrazian Podcast Resources