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Solving the Puzzle with Dr. Datis Kharrazian

Evidence-based functional medicine strategies for autoimmune, brain, and chronic health conditions.


Latest episode

  • Episode 73: Navigating Breast Implant Illness

    24:33|
    In this episode, our guest speaker, certified physician assistant Danielle Valoras explores breast implant illness (BII)—a clinical reality that remains widely misunderstood despite affecting millions of women. She unpacks why BII lacks an official diagnosis code, yet presents with a consistent constellation of symptoms, including fatigue, brain fog, joint pain, rashes, anxiety, and autoimmune-like conditions that are frequently misdiagnosed as fibromyalgia, chronic fatigue syndrome, or menopause.Danielle emphasizes the need for practitioners to consider implantable devices as contributors to immune burden. She discusses pattern recognition, the role of explantation in recovery, and why normal lab work doesn't rule out BII. Whether you're a healthcare professional, someone affected by breast implants, or curious about the intersection of implantable devices and chronic illness, this episode offers evidence-based insights you can use right away.Join us as we explore the structural and immunological mechanisms driving breast implant illness, providing practitioners with evidence-based insights to support the millions of women affected worldwide. Register at https://pages.kharrazianinstitute.com/breast-implant-illnessFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠00:00 Breast Implant Illness Symptoms Data03:41 Breast Implants and Hidden Symptoms07:10 "Understanding Breast Implant Illness"13:00 Navigating Breast Implant Shame16:04 Breast Implant Illness Awareness Growing17:26 "Understanding Symptoms and Triggers"20:55 Explantation for Improved Health24:20 Health Advice: Consult First

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  • Episode 72: How the Lymphatic System Impacts Women With Breast Implants

    32:56|
    In this episode, our guest speaker, certified physician assistant Danielle Valoras explores the essential role of the lymphatic system in women with breast implants. She explains how the lymphatic system serves as the body's drainage and immune defense network, and how disruptions in lymph flow, particularly from foreign objects such as silicone implants, can trigger a cascade of chronic inflammation, hormone imbalance, and systemic symptoms.Whether you're a healthcare professional, someone affected by breast implants, or just curious about functional medicine solutions for complex health puzzles, this episode has evidence-based insights you can use right away. Join us on February 21, 2026, as we explore the structural and immunological mechanisms driving breast implant illness, providing practitioners with evidence-based insights to support the millions of women affected worldwide. Register at https://pages.kharrazianinstitute.com/breast-implant-illnessFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠
  • Episode 71: The Hidden Risks of Breast Implants

    32:56|
    In this episode, certified physician assistant Danielle Valoras shares her expertise cultivated from over two decades in medicine—and a decade devoted to functional medicine—by diving into an issue affecting millions: breast implants and their true impact on women’s health. Drawing from both scientific research and her firsthand clinical experience working with the breast implant population for the past eight years, Danielle Valoras unpacks the complex history, construction, and ongoing health controversies surrounding these devices.From the origins of breast implants in the late 19th century to modern-day procedures and the growing global health crisis affecting up to 10 million women, Danielle Valoras guides listeners through discoveries about complications, systemic symptoms, and regulatory oversights. She highlights the urgent need for clinicians to recognize and support patients facing breast implant-related illnesses—a topic that’s often misunderstood or overlooked in mainstream medicine.Join us on February 21, 2026, as we explore the structural and immunological mechanisms driving breast implant illness, providing practitioners with evidence-based insights to support the millions of women affected worldwide. Register at https://pages.kharrazianinstitute.com/breast-implant-illnessFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠00:00 "History of Breast Implants"05:43 "Breast Implant Safety Updates"08:18 Global Breast Implant Crisis11:57 Breast Implant Risks and Reporting16:16 Silicone's Systemic Impact Explained18:50 "Platinum, Implants, and Health Risks"22:12 Breast Implant Risks & Inflammation24:31 Silicone Implants: Rupture Risks29:24 "Silicone Risks and FDA Concerns"31:45 Functional Medicine Training Resources
  • Episode 70: Nutrient-Dense Eating for Fatty Liver

    29:25|
    In this episode, Dr. Yousef Elyaman breaks down the essential nutritional strategies for reversing fatty liver disease—from macronutrient optimization to the evidence-based power of the Mediterranean diet—making complex dietary interventions immediately actionable for practitioners and patients.We explore why replacing carbohydrates with protein and saturated fats with unsaturated fats reduces hepatic fat content, how over 10,000 phytonutrients from colorful plant foods support liver detoxification in ways supplements cannot replicate, and the critical balance between omega-3 and omega-6 fatty acids. Dr. Yousef Elyaman reveals why the Mediterranean diet reduces liver fat even without weight loss—showing improvements in hepatic steatosis and insulin sensitivity independent of caloric restriction—and reviews the SMILES trial demonstrating significant mood improvements through dietary intervention alone.You'll discover practical ultra-processed food replacements patients can sustain long-term, which micronutrient deficiencies (zinc, copper, vitamin D, B-vitamins, vitamin E) drive MASH progression, and how nitrate-rich vegetables boost nitric oxide production to combat both fatty liver and hypertension. Join us for an online livestream where you'll master the functional medicine strategies that reverse fatty liver. Register now at https://pages.kharrazianinstitute.com/elyaman-fatty-liverFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠00:00 Nutrient-Dense Eating for Recovery05:57 "Risks of Ultra-Processed Foods"09:05 Omega 6 vs Omega 3 Ratio12:39 "Foods for Health and Wellness"14:44 "Benefits of Mediterranean Diet"18:19 Mediterranean Diet: Mood & Mortality Boost21:19 "Key Nutrients for Insulin Sensitivity"26:09 "Reducing Liver Fat with Diet"28:15 "Functional Medicine Training & Resources"
  • Episode 69: Ketogenic Diets and Fasting for Liver Health with Dr. Yousef Elyaman

    27:26|
    In this episode, Dr. Yousef Elyaman breaks down the essential mathematics of metabolism—from calculating basal metabolic rate to understanding the 3,500-calorie rule for weight loss—making complex concepts immediately actionable for practitioners and patients.We explore the critical distinction between fat loss and muscle preservation, why body composition matters more than the number on the scale, and how strategic protein intake and exercise can help preserve metabolic rate during caloric restriction. Dr. Yousef Elyaman shares evidence-based insights on various fasting protocols—from the foundational 12:12 time-restricted eating to modified alternate-day fasting—and reviews the latest research showing how these approaches reduce intrahepatic triglycerides, improve insulin sensitivity, and even reverse markers of liver fibrosis.Join us for an online livestream where you'll master the functional medicine strategies that reverse fatty liver. Register now at https://pages.kharrazianinstitute.com/elyaman-fatty-liverFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠00:00 "Ketogenic Diet Facts Quiz"05:37 "Tracking Body Composition Effectively"08:41 "Understanding and Testing Your BMR"12:47 "Protein's Role in Fat Loss"15:38 "Healthy Eating and Fasting Tips"17:08 Sustainable Fasting vs. Extreme Fasts23:21 "Body Fat, BMR, and Metabolism"26:15 "Solving the Puzzle Podcast Summary"
  • Episode 68: Understanding the Root Causes of Fatty Liver Disease in Functional Medicine

    26:44|
    In this episode, Dr. Yousef Elyaman, a leading functional medicine doctor, takes us into the pathogenesis of fatty liver disease, sharing his expertise on the underlying imbalances and physiological mechanisms that contribute to this complex condition.We explore how functional medicine looks beyond traditional diagnostics and treatments, focusing instead on the root causes—whether that’s insulin resistance, genetics, diet, gut health, or hormone imbalances. Dr. Elyaman breaks down how comorbidities like obesity, diabetes, cardiovascular disease, and thyroid dysfunction are interconnected and why identifying these drivers is critical for lasting, meaningful change.If you’re ready to connect cutting-edge science with practical strategies for chronic health challenges, join us for a masterclass in functional medicine with Dr. Yousef Elyaman. This episode is packed with insights you can apply immediately to improve patient outcomes or your own health journey.Join us for an online livestream where you'll master the functional medicine strategies that reverse fatty liver. Register now at https://pages.kharrazianinstitute.com/elyaman-fatty-liverFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠⁠For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠⁠For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠Timestamps:00:00 Fatty Liver: Causes & Comorbidities05:52 "Fructose, Insulin Resistance, and AGEs"09:33 "Insulin's Role in Fat Regulation"12:05 Triglycerides, LDL, and Heart Disease15:41 Fatty Liver and Iron Overload19:39 "SIBO and Digestive Health"21:28 Gut Health and Fatty Liver Connection25:32 "Functional Medicine Training & Resources"
  • Episode 67: Hallmarks of Aging and Disease

    34:24|
    In this episode, Dr. Datis Kharrazian explores longevity medicine and the hallmarks of aging and disease. How do early signs of loss of resilience—like cognitive decline or changes in physical appearance—offer clues about our biological age? What can cutting-edge studies, such as the Dunedin Longitudinal Study, teach us about predicting poor aging trajectories and preventing chronic diseases like cardiovascular issues and cancer, before they silently take hold?Dr. Kharrazian uncovers the mechanisms underlying tissue degeneration, explores why resilience is central to healthy aging, and explains how functional medicine clinicians can use biomarkers and in-depth assessments to help shift morbidity later in life. Whether you’re a healthcare practitioner, a nutrition enthusiast, or facing chronic health challenges, this episode bridges the gap between complex science and actionable steps you can implement right now.Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Longevity, Wellness, and Disease"03:51 "Pace and Markers of Aging"09:02 "Aging Mechanisms and Disease Links"13:33 Aging, Resilience, and Clinical Outcomes14:52 "Hallmarks of Aging Explained"20:11 "Aging Tissues and Inflammation"22:18 Mitochondria, Aging, and Vascular Health25:59 Cancer Warning Signs32:21 "Aging's Role in Cancer Progression"33:13 "Functional Health Solutions Podcast"