Saving Lives In Slow Motion

Coeliac Disease rates are rising across the globe. In this episode I look at what it is, why it occurs and the multitude of guises that gluten-related symptoms can take on. So many foods contain gluten (not just grains) so it is an important issue.The genetics of coeliac disease (HLAs - human leukocyte antigens): https://www.medicalnewstoday.com/articles/is-celiac-disease-hereditaryVilli and their function: https://study.com/learn/lesson/villi-in-small-intestine.htmlInnate vs adaptive immunity: https://www.ncbi.nlm.nih.gov/books/NBK279396/The rise of coeliac disease: https://www.bloomberg.com/news/newsletters/2023-01-31/rising-incidence-of-celiac-disease-spurs-interest-in-research-treatmentsNon-coeliac gluten sensitivity: https://www.sheffieldbrc.nihr.ac.uk/our-research/neuroscience/neuroinflammation/gluten-related-neurological-disorders-and-ataxiaDermatitis herpetiformis: https://my.clevelandclinic.org/health/diseases/21460-dermatitis-herpetiformisGluten ataxia and TG6-mediated neurological symptoms: https://www.sth.nhs.uk/news/2020/11/23/new-breakthrough-diagnostic-test-leads-to-earlier-detection-of-neurological-damage-caused-by-gluten-sensitivity/Sourdough: https://www.theguardian.com/lifeandstyle/2016/mar/23/sourdough-bread-gluten-intolerance-food-health-celiac-diseaseOmega-5 gliadin allergy: https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2018/wheatGAD antibodies: https://www.healthline.com/health/diabetes/gad-antibodiesHashimoto’s and gluten: https://www.healthline.com/nutrition/hashimotos-and-glutenFoods containing gluten: https://www.medicalnewstoday.com/articles/gluten-foods#foods-with-glutenAncient and modern wheat: https://pmc.ncbi.nlm.nih.gov/articles/PMC9611902/

In this episode I look at something that comes to us all, not death itself, but the run up towards it. How can we prepare for the inevitable in the best possible way? Is it even possible?Longevity as an obsession: https://www.theguardian.com/wellness/2024/sep/13/rich-men-longevity-historyUrgency culture, burnout and modern life: https://www.nationalgeographic.com/science/article/urgency-culture-burnoutBeing busy: https://www.psychologytoday.com/gb/blog/the-psychology-of-creativity/202304/the-myth-of-keeping-busyRegrets of the dying: https://bronnieware.com/blog/regrets-of-the-dying/7 types of forgetfulness: https://www.health.harvard.edu/mind-and-mood/forgetfulness-7-types-of-normal-memory-problemsCommunities around the end of life: https://pmc.ncbi.nlm.nih.gov/articles/PMC6330929/Being true to yourself: https://www.youtube.com/watch?v=vdG2yK7hoPQMeditation for the end of life: https://www.mindfulnessassociation.net/research-blogs/compassion-meditation-for-end-of-life/Physical contact at the end of life: https://www.psychologytoday.com/gb/blog/understanding-grief/201703/touching-the-dyingLegal and financial advice: https://www.macmillan.org.uk/cancer-information-and-support/impacts-of-cancer/benefits-and-financial-support/financial-help-end-of-life

Migraines are common cause of debility worldwide. In this episode I look at the causes of migraines and other types of headaches, what we can do about them and how to detect and manage them better.Links: The theories behind migraine and its mechanism: https://www.hopkinsmedicine.org/health/conditions-and-diseases/headache/how-a-migraine-happensTriptan drugs: https://migrainetrust.org/live-with-migraine/healthcare/treatments/triptans/#page-section-1MSG headaches: https://pubmed.ncbi.nlm.nih.gov/38079074/Sphenoid sinus disease (confused for migraine): https://pubmed.ncbi.nlm.nih.gov/16213927/Functional scoliosis: https://www.healthline.com/health/scoliosis/functional-scoliosis#summaryErunemab: https://migrainetrust.org/live-with-migraine/healthcare/treatments/calcitonin-gene-related-peptide-monoclonal-antibodies/Migraine as common cause of disability: https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-020-01208-0Daith piercing: https://pmc.ncbi.nlm.nih.gov/articles/PMC7075511/Acupuncture: https://migrainetrust.org/live-with-migraine/healthcare/treatments/acupuncture/

In this episode I look at Functional Medicine, a movement which started in the USA and is practised predominantly by non-medical practitioners but also increasingly medical doctors. It comes under a lot of fire from doctors and I want to explore why this, including that is isn’t ‘medicine' and what the differences and similarities are between functional medicine and conventional allopathic medicine.Links:Intro to functional medicine by IFM: https://www.ifm.org/functional-medicineA review of functional medicine by Jeffrey Bland: https://pmc.ncbi.nlm.nih.gov/articles/PMC9173848/Methylation explained: https://www.healthline.com/health/methylation#takeawayMethylation, a view from a functional medicine practitioner: https://www.drkarafitzgerald.com/2016/08/01/methylation-whats-fuss/The British College of Functional Medicine: https://www.bc-fm.org/Patient story from The Cleveland Clinic: https://my.clevelandclinic.org/patient-stories/196-functional-medicine-helps-woman-regain-her-life-after-44-years-of-chronic-painAn allopathic doctors view: https://www.doctormather.com/blog/redflagsLimitations of Evidence Based Medicine: https://www.sciencedirect.com/science/article/pii/S0735109716331370 Evidence Based Medicine: https://bmjopen.bmj.com/content/12/11/e067268

In this episode I look at a quick and easy way to take stock of your health quickly and easily to re-orientate yourself whenever you need to.It’s a great way to lay out your story, turn 'what into why', and maintain your health and head off problems before they set in. My IDEAL framework for habit change: https://www.glamourmagazine.co.uk/article/the-health-fix-dr-ayan-panja-new-years-resolutions. (There is a separate episode on this: episode 26)Yoga with Adriene on YouTube: https://www.youtube.com/user/yogawithadrieneJet lag tips: https://www.healthline.com/health/healthy-sleep/how-to-get-over-jet-lagSleep tips: https://somneesleep.com/blogs/post/matt-walker-sleep-tipsInfections: https://www.bbc.co.uk/future/article/20241119-long-fatigue-the-exhaustion-that-lingers-after-an-infectionVitamin D deficiency: https://cks.nice.org.uk/topics/vitamin-d-deficiency-in-adults/BUY THE HEALTH FIX and transform your health:  https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326/ref=tmm_pap_swatch_0

Protein is one of our three macronutrients and increasingly getting traction as being really important to our long term health. In this episode I look at why it’s so important to make sure we get enough and the right type.Sugar equivalent chart for carbohydrates: https://lowcarbfreshwell.com/what-is-a-low-carb-lifestyle/dr-unwins-sugar-infographics/Leptin and ghrelin: https://www.healthline.com/nutrition/leptin-101Macronutrients: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/nutrition/ask-the-expert/macronutrientsTrans-fats: https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/trans-fat/art-2004611410000 proteins (our proteome): https://pmc.ncbi.nlm.nih.gov/articles/PMC4889822/Sarcopenia: https://my.clevelandclinic.org/health/diseases/23167-sarcopeniaNitrites and cancer: https://www.theguardian.com/society/2022/dec/27/too-much-nitrite-cured-meat-brings-clear-risk-of-cancer-say-scientistsProtein and reduced cognitive decline: https://www.health.harvard.edu/mind-and-mood/protein-intake-associated-with-less-cognitive-declineDoctors Kitchen protein calculator (Dr Rupy Aujla): https://www.thedoctorskitchen.com/protein_calculator.php

Air pollution is a huge cause of death killing 8 million people worldwide each year. Its effects are damaging to most of our body systems yet is an ‘invisible’ threat to us. In this episode I look at what we can do to minimise our exposure to air pollutants in and out of the home.WHO guidelines: https://www.who.int/publications/i/item/9789240034228Pesticides and Parkinson’s Disease: https://pubmed.ncbi.nlm.nih.gov/32919961/Air pollution and non-communicable diseases: https://pmc.ncbi.nlm.nih.gov/articles/PMC6904854/Smoke control at home: https://www.gov.uk/smoke-control-area-rulesCarpets and health: https://pmc.ncbi.nlm.nih.gov/articles/PMC5858259/Mould and illness: https://pmc.ncbi.nlm.nih.gov/articles/PMC7231651/Plants and air purification: https://pmc.ncbi.nlm.nih.gov/articles/PMC8279815/My report for the BBC from Hong Kong on air pollution comparing types: https://www.bbc.co.uk/news/av/health-35885569

Magnesium is an important mineral for our health and in this episode I look at why it has become a silent public health issue in recent years. I cover where magnesium comes from, why deficiency has become so prevalent and what to do about it. Food sources of magnesium: https://nutritionsource.hsph.harvard.edu/magnesium/Sublinical magnesium deficiency: https://openheart.bmj.com/content/5/1/e000668Getting enough magnesium and why blood testing is often inaccurate: https://pmc.ncbi.nlm.nih.gov/articles/PMC6316205/An old study about CO2 and plant mineralisation: https://pubmed.ncbi.nlm.nih.gov/24867639/The decline of plant nutrition: https://pubmed.ncbi.nlm.nih.gov/36336557/Vitamin D and magnesium: https://www.sciencedirect.com/science/article/abs/pii/S0899900722000867A campaign for remineralising soil: https://www.remineralize.org/Examine.com - evidence based information on supplements 

In this episode I go back to the basics of how to get themes out now your GP appointment beyond the obvious. Medicine is increasingly complex and time is often short with the doctor. Here are my tips for an effective use of appointments in 2025.Links:Why men don’t gp to the doctor - https://www.bowelresearchuk.org/latest-news/why-dont-men-go-to-see-their-doctors/Hello My Name is: https://www.hellomynameis.org.uk/Continuity: https://www.pulsetoday.co.uk/news/workload/continuity-of-care-more-productive-than-access-driven-gp-models-study-suggests/Giving the doctor a good history: https://www.forbes.com/sites/carolynmcclanahan/2019/01/19/how-to-give-a-good-medical-history-to-get-better-health-care/Reasonable adjustments: https://www.mind.org.uk/information-support/legal-rights/disability-discrimination/reasonable-adjustments/