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Why breast cancer treatments might work best just after your period
Breast cancer cells are more susceptible to chemotherapy at certain points in the menstrual cycle, new data in Nature suggests. Researchers studied the equivalent hormonal cycle in mice and found that during the oestrous phase, where progesterone levels are low, tumours are more susceptible to chemotherapy. The same effect was shown in humans in a small retrospective study. The team caution that a larger clinical trial would need to be conducted, but hope that this work could open up an, easy to implement, way to boost the effect of chemotherapy.
Research Article: Bornes et al.
News and Views: What is the best time of the month to treat breast cancer?
09:22 Research Highlights
How coffee changes your gut microbiota, and the first amber deposits found in Antarctica hint at an ancient rainforest.
Research Highlight: Do you drink coffee? Ask your gut
Research Highlight: Antarctica’s first known amber whispers of a vanished rainforest
11:47 Is human-level artificial intelligence close?
The latest AI system released by OpenAI, the makers of ChatGPT, is better able to break down problems into smaller chunks, making it closer to a human way of solving problems than other systems. This has reignited discussions about the likelihood of AIs achieving human-level intelligence. Although previously the realm of science fiction, researchers are now taking the idea of ‘artificial general intelligence’, or AGI, more seriously. Although this technology has the potential to help tackle humanity's biggest challenges, there are concerns about the safety of such technology if it were to become autonomous.
News Feature: How close is AI to human-level intelligence?
21:43 Briefing Chat
How making a bank of centenarians’ stem cells could help unlock the secrets of healthy ageing, and what some 1.5 million year old footprints reveal about how ancient hominin species may have interacted.
Nature: What’s the secret to living to 100? Centenarian stem cells could offer clues
Nature: These two ancient human relatives crossed paths 1.5 million years ago
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Briefing Chat: Are scientists funny? The evidence is in — and it's no joke
09:52|In this episode:00:22 Exploring how gut microorganisms contribute to ageingNature: Memory loss is fuelled by gut microbes in ageing mice04:30 How good jokes are in short supply during academic conferencesNature: Knock knock, no one’s there. Study finds scientists’ jokes mostly fall flatSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Botanical mystery solved: how plants make a crucial malaria drug
15:55|In this episode:00:46 Piecing together a biochemical puzzleResearch Article : Lombe et al.12:26 Research HighlightsNature: Electric-vehicle batteries toughen up to beat the heatNature: Live parrots were carried across the Andes before the Incas’ rise
Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
10:34|00:26 Why researchers keep using Doom in their researchNature: How the classic computer game Doom became a tool for scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.This fish shouldn’t exist — the weird genetics of clonal vertebrates
23:22|A study reveals how the asexual Amazon molly defies evolutionary expectations — plus, evidence of what may be powering superluminous supernovae.In this episode:00:46 Unravelling the genetics of an asexual fish that should be extinctResearch Article: Ricemeyer et al.News and Views: How an all-female fish species defies evolutionary expectations10:19 Research HighlightsNature: Jam-packed star system is most compact of its kind ever foundNature: Peanut-processing microbes ward off dangerous allergic shock11:31 How a superluminous supernova got so brightResearch Article : Farah et al.News and Views: Ultra-bright supernova wobbles like a spinning topSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: https://www.nature.com/briefing/signup
Briefing chat: What Galileo’s scribbled margin notes reveal about his scientific journey
09:35|In this episode:00:25 How paediatricians’ antibodies could treat serious viral infectionsNew Scientist: Paediatricians’ blood used to make new treatments for RSV and colds04:22 Galileo’s annotations in an ancient textScience: Galileo’s handwritten notes found in ancient astronomy textSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Heart surgery with quick-setting magnetic fluid could prevent strokes
18:12|Injectable fluid safely fills area in which blood clots can form, in animal trials — plus, strong evidence that an elusive form of diamond has been made in the lab.00:47 A magnetic seal to stop clots forming in the heartResearch Article : Wang et al.News and Views: Magnetic fluid offers better seal in heart-plugging medical procedureVideo: Magnetic gel injected into the heart could stop strokes07:02 Research HighlightsNature: Sewage systems secretly waft pollution into the airNature: This ant species is composed of only queens — no workers or males11:31 Making hexagonal diamondResearch Article: Lai et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Audio long read: Many people have no mental imagery. What’s going on in their brains?
18:23|This is an audio version of our Feature: Many people have no mental imagery. What’s going on in their brains?
Briefing chat: Pokémon turns 30 — how Pikachu and pals inspired generations of researchers
11:05|In this episode:00:15 How Pokémon inspired fields as diverse as evolution, biodiversity and research integrityNature: Pokémon turns 30 — how the fictional pocket monsters shaped scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.How earthquakes and lightning help explain squeaky sneakers
19:35|High-speed footage reveals shoe squeaks can start with a tiny bolt of lightning — plus, evidence that a debated brain phenomenon exists in humans.00:44 The science of squeaky shoesResearch Article : Djellouli et al.Basketball sound effects via Bradley Kanaris/Getty.09:05 Research HighlightsNature: Runaway black hole leaves a trail of starsNature: Super-sticky feet help a robot to climb the walls11:31 Evidence of hippocampal neurogenesisResearch Article: Disouky et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.