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Insulin cream offers needle-free option for diabetes
Researchers have developed a skin-permeable polymer that can deliver insulin into the body, which they say could one day offer an alternative to injections for diabetes management. The skin’s structure presents a formidable barrier to the delivery of large drugs but in this work a team show that their polymer can penetrate though the different layers without causing damage. Insulin attached to this polymer was able to reduce blood glucose levels in animal models for diabetes at a comparable speed to injected insulin. While further research is required on the long-term safety of this strategy, the team hope it could offer a way to non-invasively deliver other large-molecule drugs into the body.
Research Article: Wei et al.
How extreme drought may be humanity’s biggest challenge after a huge volcanic eruption — plus, turning a bacterium into a factory for a colour-changing pigment
Research Highlight: Volcano mega-eruptions lead to parched times
Research Highlight: Dye or die: bacterium forced to make pigment to stay alive
The human brain responds in a similar way to both familiar and unfamiliar languages, but there are some key differences, according to new research — a finding that may explain why learning a language can be difficult. A study looking involving 34 people showed that listening to an unfamiliar language triggers similar neural activity to listening to their native tongue. The finding implies that human speech triggers a common reaction in the brain regardless of understanding. However, there were subtle differences when listening to a known language that may help explain how people actually understand words.
Research Article: Bhaya-Grossman et al.
Neuron: Zhang et al
Signs that greenhouse-gas emissions may peak around 2030 — plus, evidence of dog breeding by ancient humans.
Nature: Global greenhouse-gas emissions are still rising: when will they peak?
Nature: How ancient humans bred and traded the first domestic dogs
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Briefing Chat: Why scientists made papyrus scrolls, then burnt them
11:32|In this episode00:23 How detecting lead could help researchers read damaged Roman scrollsNature: Watch scientists decipher burned scrolls without unrolling them06:42 A biodegradeable, paper-inspired batteryNature: Edible batteries power medical devices in the bodySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Never miss an episode. Subscribe to the Nature Podcast on Apple Podcasts, Spotify, YouTube Music or your favourite podcast app. An RSS feed for the Nature Podcast is available too.
Bank accounts reveal the fingerprints of abusive financial control
24:12|00:45 Investigating the day-to-day impacts of Financial AbuseNature: Trendl et al.Support organizationsUK: Surviving Economic AbuseUS: National Domestic Violence Helpline12:14 Research HighlightsNature: Mercury is shrinking with age — faster than thoughtNature: Cognitive resilience helps to predict Alzheimer’s dementia14:55 How opposing forces in the Earth's core alter how the planet spinsNature: Gravitational tug-of-war inside Earth is changing the length of our daysSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Never miss an episode. Subscribe to the Nature Podcast on Apple Podcasts, Spotify, YouTube Music or your favourite podcast app. An RSS feed for the Nature Podcast is available too.- 12:34|In this episode:00:22 Could secret rooms lie beyond Tutankhamun's tomb?Nature: Exclusive: New evidence for hidden chambers beyond Tutankhamun’s tomb05:55 A multifunctional brain–computer interfaceNature: ‘Multifunctional’ brain implant translates speech and gestures in real timeSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Transplanted human brain-tissue takes root in mice without a cortex
28:10|In this episode:00:46 Human brain-organoids transplanted into mice missing their cortexNature: Human brain cells transplanted into mice in ‘most extensive’ integration ever13:51 Research HighlightsNature: Ruins of ancient Asian city show engineering prowess and organizationNature: Distant sensors announced a fearsome tsunami’s birth16:16 Paper2Agent: the AI tool that lets researchers talk to papersNature: AI tool turns any paper into an ‘agent’ that can collaborate and answer complex queriesSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: The Bunsen burner myth that turns out to be just hot air
15:55|Nature staff discuss an AI tool that can assess the impact of nine billion mutations — plus, how the Bunsen burner’s reputation for sterilization may be based on tradition alone.00:21 Deepmind’s new tool helps scientists find the impact of mutationsNature: DeepMind’s new genome ‘atlas’ charts effects of all nine billion human gene mutations07:10 Bacteria can still contaminate plates near to active Bunsen burnersNature: Bunsen burners’ reputation for sterilizing workplaces flames out Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Phone tutoring boosts math scores when schools are forced to close
21:10|In this episode:00:46 How telephone teaching could boost education during school shutdownsNature: Pick up the phone! Phone calls with tutors keep kids learning when schools shut down11:42 Research HighlightsNature: Super-precise optical clocks in four nations tick in harmonyNature: These greenhouse-gas sources have trotters and snouts14:15 Why atlases might need an updateNature: Hello Equal Earth: what the UN’s new world map will changeSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: How 1,000 pairs of buried underpants helped measure soil health
12:24|In this episode:00:21 Our picks of this year’s Ig Nobel prizesNature: Buried underpants and a new definition of kissing win 2026 Ig Nobel prizes07:47 Massive xenon experiment detects tantalizing hint of dark matterNature: Is this the first glimpse of dark matter? Data point excites physicistsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Audio long read: Could mending damaged DNA prolong life?
18:16|Scientists are amassing evidence that unrepaired or poorly repaired DNA damage underlies many of the hallmarks of ageing. This has led to research into whether boosting DNA repair can keep people healthy for longer.This is an audio version of our Feature: Could mending damaged DNA prolong life?
Briefing Chat: How Dolly Parton left her mark on science
14:05|In this episode:00:18 Researchers celebrate Dolly Parton's contributions to scienceNature: Dolly Parton dies aged 80 — researchers celebrate her contributions to science08:40 Phase III trial of melanoma vaccine shows promiseNature: Moderna cancer vaccine stops melanoma returning: what’s next for personalized treatments?Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
