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Insulin cream offers needle-free option for diabetes
Researchers have developed a skin-permeable polymer that can deliver insulin into the body, which they say could one day offer an alternative to injections for diabetes management. The skin’s structure presents a formidable barrier to the delivery of large drugs but in this work a team show that their polymer can penetrate though the different layers without causing damage. Insulin attached to this polymer was able to reduce blood glucose levels in animal models for diabetes at a comparable speed to injected insulin. While further research is required on the long-term safety of this strategy, the team hope it could offer a way to non-invasively deliver other large-molecule drugs into the body.
Research Article: Wei et al.
How extreme drought may be humanity’s biggest challenge after a huge volcanic eruption — plus, turning a bacterium into a factory for a colour-changing pigment
Research Highlight: Volcano mega-eruptions lead to parched times
Research Highlight: Dye or die: bacterium forced to make pigment to stay alive
The human brain responds in a similar way to both familiar and unfamiliar languages, but there are some key differences, according to new research — a finding that may explain why learning a language can be difficult. A study looking involving 34 people showed that listening to an unfamiliar language triggers similar neural activity to listening to their native tongue. The finding implies that human speech triggers a common reaction in the brain regardless of understanding. However, there were subtle differences when listening to a known language that may help explain how people actually understand words.
Research Article: Bhaya-Grossman et al.
Neuron: Zhang et al
Signs that greenhouse-gas emissions may peak around 2030 — plus, evidence of dog breeding by ancient humans.
Nature: Global greenhouse-gas emissions are still rising: when will they peak?
Nature: How ancient humans bred and traded the first domestic dogs
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Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
10:34|00:26 Why researchers keep using Doom in their researchNature: How the classic computer game Doom became a tool for scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
This fish shouldn’t exist — the weird genetics of clonal vertebrates
23:22|A study reveals how the asexual Amazon molly defies evolutionary expectations — plus, evidence of what may be powering superluminous supernovae.In this episode:00:46 Unravelling the genetics of an asexual fish that should be extinctResearch Article: Ricemeyer et al.News and Views: How an all-female fish species defies evolutionary expectations10:19 Research HighlightsNature: Jam-packed star system is most compact of its kind ever foundNature: Peanut-processing microbes ward off dangerous allergic shock11:31 How a superluminous supernova got so brightResearch Article : Farah et al.News and Views: Ultra-bright supernova wobbles like a spinning topSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday: https://www.nature.com/briefing/signup
Briefing chat: What Galileo’s scribbled margin notes reveal about his scientific journey
09:35|In this episode:00:25 How paediatricians’ antibodies could treat serious viral infectionsNew Scientist: Paediatricians’ blood used to make new treatments for RSV and colds04:22 Galileo’s annotations in an ancient textScience: Galileo’s handwritten notes found in ancient astronomy textSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Heart surgery with quick-setting magnetic fluid could prevent strokes
18:12|Injectable fluid safely fills area in which blood clots can form, in animal trials — plus, strong evidence that an elusive form of diamond has been made in the lab.00:47 A magnetic seal to stop clots forming in the heartResearch Article : Wang et al.News and Views: Magnetic fluid offers better seal in heart-plugging medical procedureVideo: Magnetic gel injected into the heart could stop strokes07:02 Research HighlightsNature: Sewage systems secretly waft pollution into the airNature: This ant species is composed of only queens — no workers or males11:31 Making hexagonal diamondResearch Article: Lai et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Audio long read: Many people have no mental imagery. What’s going on in their brains?
18:23|This is an audio version of our Feature: Many people have no mental imagery. What’s going on in their brains?
Briefing chat: Pokémon turns 30 — how Pikachu and pals inspired generations of researchers
11:05|In this episode:00:15 How Pokémon inspired fields as diverse as evolution, biodiversity and research integrityNature: Pokémon turns 30 — how the fictional pocket monsters shaped scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.How earthquakes and lightning help explain squeaky sneakers
19:35|High-speed footage reveals shoe squeaks can start with a tiny bolt of lightning — plus, evidence that a debated brain phenomenon exists in humans.00:44 The science of squeaky shoesResearch Article : Djellouli et al.Basketball sound effects via Bradley Kanaris/Getty.09:05 Research HighlightsNature: Runaway black hole leaves a trail of starsNature: Super-sticky feet help a robot to climb the walls11:31 Evidence of hippocampal neurogenesisResearch Article: Disouky et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing chat: How hovering bumblebees keep their cool
13:59|00:25 How brains differ by sex and ageNature: Brain differences between sexes get more pronounced from puberty07:14 Bumblebees ‘fan themselves’ during flight to keep coolScience: How do busy bees avoid overheating from flying?Video: Birds gliding through bubbles reveal aerodynamic trickSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.This chunk of glass could store two million books for 10,000 years
21:40|00:46 Data stored in glassNature: Microsoft Research Project Silica TeamNature: Microsoft team creates 'revolutionary' data storage system that lasts for millennia08:09 Research HighlightsNature: Parasitic wasps use tamed virus to castrate caterpillarsNature: Flexible joints: robot morphs into a range of cyborg species10:10 An mRNA vaccine for Triple-Negative Breast CancerNature: Sahin et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.