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Male mice can grow female organs — if their mothers lack iron
Iron deficiency in mice mothers can sometimes result in their offspring developing female sex organs despite having male sex genes, according to new research. While genetics has been thought to be the primary factor in determining offspring sex in mammals, the new work shows that a lack of iron disrupts an enzyme involved in the development of testes, leading to some mice with male sex-determining genes being born with female genitalia and ovaries. This suggests that sex determination is controlled by more than genetics, but more work will need to be done to understand the precise mechanisms involved.
News: Male mice can grow ovaries if their pregnant mums are iron deficient
Research article: Okashita et al.
How climate change is making dust storms more likely, and understanding the genetics of a boy who couldn’t feel pain.
Research Highlight: The perfect storm for dust storms, thanks to global warming
Research Highlight: CRISPR helps to show why a boy felt no pain
The contributions that small-scale fishers make to sustainable fishing have been described as ‘invisible’, but now a huge research project has revealed the role this community plays in feeding populations and protecting oceans. Looking at data from 58 countries, researchers have shown that small-scale fishers account for around 40% of the global catch and feed approximately 25% of the world’s population. The people behind the initiative hope that these data can help give a voice to small-scale fishers as people look for ways to feed the world sustainably.
Immersive : Small-scale fisheries
The discovery of an ‘ambidextrous’ protein; and why humpback whales, despite their enormous eyes, appear to be shortsighted.
Nature: Rare ‘ambidextrous’ protein breaks rules of handedness
Discover Magazine: Big Eyes, Blurry Vision: Why Humpback Whales Struggle to See Clearly
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Togetherness: How co-operation built the world
31:39|In this episode, we speak with science journalist Rowan Hooper, whose book Togetherness: Symbiosis and the Hidden Story of Life's Greatest Collaborations takes a deep-dive into the world of co-operation between organisms.In the book, he argues that collaboration in nature has often been overlooked in favour of competition, and that organisms working together have played a vital role in making the world the way it is.Togetherness: Symbiosis and the Hidden Story of Life's Greatest Collaborations Rowan Hooper Fern Press (2026)Music supplied by SPD/Triple Scoop Music/Getty Images
Audio long read: Is the peptide craze backed by science? The promise behind the hype
16:41|Peptides — short chains of amino acids — have become huge online. The popularity of these molecules has skyrocketed and they are now the latest cure-all trend on social media.But what does the science say about their effectiveness? Animal research suggests that that some of these experimental peptides hold promise, but evidence they work in people is lacking.This is an audio version of our Feature: Is the peptide craze backed by science? The promise behind the hype
Briefing Chat: What tickling a chimpanzee can tell us about the evolution of speech
11:30|Nature staff discuss how apes share a rhythm of laughter, and how AI use may degrade skills in medicine and computer science.00:32 Early evidence suggests that AI use causes skills to atrophyNature: Is AI ruining our skills? Early results are in — and they’re not good06:42 Humans and chimps share a laughNature: Oo oo, ha ha: why humans and great apes giggle alike when tickledSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Medical records could be revealed by AI training-data vulnerability
19:54|In this episode:00:46 How sensitive information can be gleaned from medical AIsResearch article: Knolle et al.Correction: The story about medical AI-data privacy incorrectly stated that the number of individuals at high risk of a membership inference attack increases as training-dataset size grows. It should have stated that the increase in risk occurs when the AI model increases in capacity and size.11:31 Research HighlightsNature: A long-lived butterfly’s secret to graceful ageingNature: It slices! It dices! Sashimi-Bot handles seafood with ease13:57 Across the Universe, galaxies clump together more than physicists thought they shouldResearch article: Labini & GaloppoSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Testosterone and sperm may get a boost from obesity drugs
12:16|Nature staff discuss preliminary data on the effects of GLP-1 drugs on male fertility plus a two-year trial of a brain-computer interface.00:18 Brain-computer interface makes a life-changing impactNature: At-home brain implant gives man with motor neuron disease his daily life back05:39 The possible benefits of obesity drugs on testosteroneNature: The latest benefit of obesity drugs: boosting testosterone and sperm qualitySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.DNA from hunter-gatherer teeth reveals secrets of ancient plague
26:42|In this episode:00:45 Ancient evidence of deadly plague outbreaksResearch article: Macleod et al.12:33 Research HighlightsNature: Bones of Iron Age skeleton were whittled into toolsNature: Giant crustacean of the deep sea steals a trick from bacteria14:52 A prototype atom interferometerResearch article: Baynham et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: The epic journey of Stonehenge’s central stone
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Briefing chat: Spinosaurs with salt glands could have lived in marine environments
11:25|In this episode:00:23 Fossil evidence that spinosaurs had an aquatic lifestyleScience: Some spinosaurs cried salty tears to thrive in brackish waters04:57 The explosive immune cells that kill in minutesNature: Bang! Exploding immune cells splatter potent toxins everywhereSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.