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How a dangerous tick-borne virus sneaks into the brain
Researchers have identified a key protein that helps tick-borne encephalitis virus enter the brain. In rare cases an infection can lead to serious neurological symptoms, but little was known about how the virus interacts with human cells. Now, a team show that a protein found on the outside of cells plays an important role in infection. In mouse experiments, they show that blocking the ability of the virus to bind to this protein protected the mice from disease. Currently no treatments exist, but the team hopes that this research will ultimately lead to a viable drug for this disease.
Research Article: Mittler et al.
The squirming robot that speeds up the insertion of an emergency breathing tube — plus, the 10,000-year-old remains that could be the oldest intentionally preserved mummies
Research Highlight: Soft robot steers itself down the human airway
Research Highlight: Smoke-dried mummies pre-date Egypt’s embalmed bodies
To assess the potential impact of cuts to funding by the Trump administration, Nature trained a machine-learning bot to try and reproduce the NIH’s method of cancelling grants and applied it to science that was successfully funded around ten years ago. This thought experiment shows that highly impactful science and medical research might have been at risk had a similar process been followed a decade ago, revealing the potentially broad-reaching consequences of these actions today.
Nature Index: What research might be lost after the NIH’s cuts? Nature trained a bot to find out
News: Are the Trump team’s actions affecting your research? How to contact Nature
What researchers understand about chatbot-induced psychosis, and the AI designed viruses capable of killing E. coli bacteria.
Nature: Can AI chatbots trigger psychosis? What the science says
Nature: World’s first AI-designed viruses a step towards AI-generated life
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Briefing Chat: What tickling a chimpanzee can tell us about the evolution of speech
11:30|Nature staff discuss how apes share a rhythm of laughter, and how AI use may degrade skills in medicine and computer science.00:32 Early evidence suggests that AI use causes skills to atrophyNature: Is AI ruining our skills? Early results are in — and they’re not good06:42 Humans and chimps share a laughNature: Oo oo, ha ha: why humans and great apes giggle alike when tickledSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Medical records could be revealed by AI training-data vulnerability
19:54|In this episode:00:46 How sensitive information can be gleaned from medical AIsResearch article: Knolle et al.Correction: The story about medical AI-data privacy incorrectly stated that the number of individuals at high risk of a membership inference attack increases as training-dataset size grows. It should have stated that the increase in risk occurs when the AI model increases in capacity and size.11:31 Research HighlightsNature: A long-lived butterfly’s secret to graceful ageingNature: It slices! It dices! Sashimi-Bot handles seafood with ease13:57 Across the Universe, galaxies clump together more than physicists thought they shouldResearch article: Labini & GaloppoSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Testosterone and sperm may get a boost from obesity drugs
12:16|Nature staff discuss preliminary data on the effects of GLP-1 drugs on male fertility plus a two-year trial of a brain-computer interface.00:18 Brain-computer interface makes a life-changing impactNature: At-home brain implant gives man with motor neuron disease his daily life back05:39 The possible benefits of obesity drugs on testosteroneNature: The latest benefit of obesity drugs: boosting testosterone and sperm qualitySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
DNA from hunter-gatherer teeth reveals secrets of ancient plague
26:42|In this episode:00:45 Ancient evidence of deadly plague outbreaksResearch article: Macleod et al.12:33 Research HighlightsNature: Bones of Iron Age skeleton were whittled into toolsNature: Giant crustacean of the deep sea steals a trick from bacteria14:52 A prototype atom interferometerResearch article: Baynham et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: The epic journey of Stonehenge’s central stone
11:20|In this episode:00:37 Evidence that Stonehenge's Altar Stone travelled by glacierBBC Science Focus: We may have just cracked one of Stonehenge's greatest mysteries05:44 Fossilized faeces reveal DNA from ancient ecosystemNature: Ancient ground squirrels feasted on carcasses like ‘zombies of the Pleistocene’Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Newly-discovered whale graveyard dates back millions of years
21:38|In this episode:00:46 A giant, ancient whale necropolisResearch article: Peng et al.News & Views: A vast whale necropolis has been found08:52 Research HighlightsNature: Babies’ birth weight improves with help of payments to parentsNature: Earliest signs of vision recorded in ancient sea-floor tracks11:11 Turning plant material into chemical building-blocksResearch article: Mains et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing chat: Spinosaurs with salt glands could have lived in marine environments
11:25|In this episode:00:23 Fossil evidence that spinosaurs had an aquatic lifestyleScience: Some spinosaurs cried salty tears to thrive in brackish waters04:57 The explosive immune cells that kill in minutesNature: Bang! Exploding immune cells splatter potent toxins everywhereSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Your phone can use tiny skin-colour changes to measure your heart rate
18:23|In this episode:00:57 How your smartphone’s camera could measure your heart rateResearch article: Liao et al.08:55 Research HighlightsNature: A star gone rogue tears through the GalaxyNature: Gold keeps glittering courtesy of surface chemistry11:04 Should you try something new in a restaurant? Maths has the answerNature: Feynman solved the ‘restaurant dilemma’ 50 years ago — now a study confirms his mathematicsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: When to trust eyewitness memory – according to science
17:14|In this episode:00:21 When witnesses identify suspects from police line-ups, confidence mattersNature: Memory on trial: the new science of when to trust eyewitness testimony07:15 Registered Reports: how this ‘double peer review’ process could benefit scientists and their resultsNature: Nature is expanding Registered Reports to all the fields in which we publish