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How a dangerous tick-borne virus sneaks into the brain
Researchers have identified a key protein that helps tick-borne encephalitis virus enter the brain. In rare cases an infection can lead to serious neurological symptoms, but little was known about how the virus interacts with human cells. Now, a team show that a protein found on the outside of cells plays an important role in infection. In mouse experiments, they show that blocking the ability of the virus to bind to this protein protected the mice from disease. Currently no treatments exist, but the team hopes that this research will ultimately lead to a viable drug for this disease.
Research Article: Mittler et al.
The squirming robot that speeds up the insertion of an emergency breathing tube — plus, the 10,000-year-old remains that could be the oldest intentionally preserved mummies
Research Highlight: Soft robot steers itself down the human airway
Research Highlight: Smoke-dried mummies pre-date Egypt’s embalmed bodies
To assess the potential impact of cuts to funding by the Trump administration, Nature trained a machine-learning bot to try and reproduce the NIH’s method of cancelling grants and applied it to science that was successfully funded around ten years ago. This thought experiment shows that highly impactful science and medical research might have been at risk had a similar process been followed a decade ago, revealing the potentially broad-reaching consequences of these actions today.
Nature Index: What research might be lost after the NIH’s cuts? Nature trained a bot to find out
News: Are the Trump team’s actions affecting your research? How to contact Nature
What researchers understand about chatbot-induced psychosis, and the AI designed viruses capable of killing E. coli bacteria.
Nature: Can AI chatbots trigger psychosis? What the science says
Nature: World’s first AI-designed viruses a step towards AI-generated life
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Briefing Chat: Anthropic rolls out new AI watermark — will it make a difference?
16:52|In this episode:00:29 What does Anthropic’s new watermark mean for research?Nature: Can Anthropic’s invisible watermarks curb ‘AI slop’? Researchers remain sceptical10:57 Ticklishness is a distinct, specialized body sensation, research findsNature: Where are you ticklish? Researchers map the sensation across culturesSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
The probiotic bacteria engineered to treat diabetes
19:37|Genetically modified bacteria lower high blood-sugar in animal trials — plus, how to safely watch a solar eclipse.00:45 A living diabetes treatmentResearch article: Guan et al.08:03 Research HighlightsNature: Pumas are drivers’ guardian angelsNature: How a steady drip-drip can erode the hardest stone10:29 What eclipses might reveal about the Sun’s coronaNature: Solar eclipse offers rare chance to solve Sun’s magnetic-field mysteriesSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Is DNA repair the secret to a long life? Whales and mole-rats offer tantalizing hints
13:52|Nature staff discuss how animal studies are starting to uncover how DNA repair could prolong life, and how COVID-19 can reawaken dormant viruses.00:25 Could reawakened viruses have a link to long-COVID?Nature: COVID can wake up a slew of dormant viruses inside you05:57 DNA damage can cause ageing, could boosting repair boost longevity?Nature: Could mending damaged DNA prolong life?Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Junk plastic turns into high-value commodity with chemistry trick
13:01|Researchers untangle the chemistry behind turning PVC into high-grade motor lubricant — plus, how engineered yeast can help make a cancer drug.00:45 The chemistry behind converting PVC into lubricantResearch article: Munyaneza et al.09:15 Research HighlightsNature: Engineered yeast that make cancer drugs could spare a rare flowerNature: Sickle-cell disease linked to prematurely aged stem cells in miceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Orcas smashed a sunfish to bits — researchers aren't sure why
14:18|In this episode:00:24 The quest to count the Amazon's insectsNature: Tiny patch of Amazon likely holds 40,000 insect species — many new to science07:31 The orcas that exploded a sunfishThe Guardian: Orcas seen ramming prey so hard it explodes may be playing gameTiktok: Orcas vs sunfishSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Earthworks spotted in the Amazon hint at huge ancient civilization
20:30|In this episode:00:45 Ancient structures hidden beneath the Amazon’s canopyResearch article: Pärssinen et al.09:15 Research HighlightsNature: It’ll grow on you: live fungi formed into sustainable fashionPhysical Review Fluids: Gourmandie et al.11:48 Tiny fossils represent the earliest-known squid ancestorResearch article: Song et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Baby T. rex were killers from birth, suggest new fossils
12:43|Nature staff discuss the young but deadly dinosaur kings, the prowess of ancient Egyptian princesses, and how London is becoming the world’s AI safety capital.00:34 London is transforming into an AI-safety hubNature: A global capital for AI safety is emerging — and it’s not in Silicon Valley05:52 Bones reveal that ancient Egyptian princesses weren’t pamperedScientific American: Ancient Egyptian princesses were ‘powerful’ weapon users, new analysis suggests9:30 T. rex was born ready to killDiscover magazine: Fossil Evidence Indicates Baby T. rex Were Tiny, but DeadlySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
What counts as a moon? Huge ‘exosatellite’ sparks debate
23:50|00:45 The discovery of a moon-like object in a distant star systemResearch article: Hoy et al.10:34 Research HighlightsNature: Moving floors keep buildings from swaying with the windNature: Wearable sensors on the face are invisible to the eye13:07 A discovery of a new type of rare transmissible-cancerResearch article: Curd et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Sweet! Elusive sugar molecules found in space
09:55|In this episode:00:24 A sweet discovery near the Milky Way’s centreNature: First ‘true sugar’ molecule found in space — offering hints to life’s origins05:05 Mathematical texts give insights into Maya mathematical prowessNature: Mathematics formula found on Maya wall rivals insights of ancient mastersSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.