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How a dangerous tick-borne virus sneaks into the brain
Researchers have identified a key protein that helps tick-borne encephalitis virus enter the brain. In rare cases an infection can lead to serious neurological symptoms, but little was known about how the virus interacts with human cells. Now, a team show that a protein found on the outside of cells plays an important role in infection. In mouse experiments, they show that blocking the ability of the virus to bind to this protein protected the mice from disease. Currently no treatments exist, but the team hopes that this research will ultimately lead to a viable drug for this disease.
Research Article: Mittler et al.
The squirming robot that speeds up the insertion of an emergency breathing tube — plus, the 10,000-year-old remains that could be the oldest intentionally preserved mummies
Research Highlight: Soft robot steers itself down the human airway
Research Highlight: Smoke-dried mummies pre-date Egypt’s embalmed bodies
To assess the potential impact of cuts to funding by the Trump administration, Nature trained a machine-learning bot to try and reproduce the NIH’s method of cancelling grants and applied it to science that was successfully funded around ten years ago. This thought experiment shows that highly impactful science and medical research might have been at risk had a similar process been followed a decade ago, revealing the potentially broad-reaching consequences of these actions today.
Nature Index: What research might be lost after the NIH’s cuts? Nature trained a bot to find out
News: Are the Trump team’s actions affecting your research? How to contact Nature
What researchers understand about chatbot-induced psychosis, and the AI designed viruses capable of killing E. coli bacteria.
Nature: Can AI chatbots trigger psychosis? What the science says
Nature: World’s first AI-designed viruses a step towards AI-generated life
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Briefing chat: Pokémon turns 30 — how Pikachu and pals inspired generations of researchers
11:05|In this episode:00:15 How Pokémon inspired fields as diverse as evolution, biodiversity and research integrityNature: Pokémon turns 30 — how the fictional pocket monsters shaped scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
How earthquakes and lightning help explain squeaky sneakers
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Briefing chat: How hovering bumblebees keep their cool
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This chunk of glass could store two million books for 10,000 years
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Briefing Chat: Caffeine slows brain ageing, suggests decades of data
09:52|In this episode:00:26 Moderate caffeine intake might reduce dementia risk, study suggestsNature: Coffee linked to slower brain ageing in study of 130,000 people04:15 Using AI to work out the rules of a long-forgotten board gameScientific American: Rules of mysterious ancient Roman board game decoded by AISubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
These hungry immune cells tidy sleeping flies' brains
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Briefing Chat: 'External lungs' keep man alive for 48 hours until transplant
11:03|In this episode:00:42 External, artificial-lung system keeps patient alive for transplantNature: 48 hours without lungs: artificial organ kept man alive until transplant06:22 How lung cancer in mice hijacks neurons to outwit the immune systemNature: How tumours trick the brain into shutting down cancer-fighting cellsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
These mysterious ridges could help skin regenerate
22:05|00:46 Understanding how rete ridges form in the skinNature: Thompson et al.09:32 Research HighlightsNature: Genetically engineered ‘stinkweed’ comes up roses for making seed oilNature: Largest galaxy survey yet confirms that the Universe is not clumpy enough11:52 The open-source AI that performs scientific literature reviewsNature: Asai et al.Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: What Brazilian centenarians could reveal about the science of ageing
10:21|In this episode:00:36 Study probes genetics of extreme longevityNature: Still working at 107: supercentenarian study probes genetics of extreme longevity05:32 Controlling fluorescent proteins’ brightness with magnetsNature: ‘Remote controlled’ proteins illuminate living cellsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.