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How a dangerous tick-borne virus sneaks into the brain
Researchers have identified a key protein that helps tick-borne encephalitis virus enter the brain. In rare cases an infection can lead to serious neurological symptoms, but little was known about how the virus interacts with human cells. Now, a team show that a protein found on the outside of cells plays an important role in infection. In mouse experiments, they show that blocking the ability of the virus to bind to this protein protected the mice from disease. Currently no treatments exist, but the team hopes that this research will ultimately lead to a viable drug for this disease.
Research Article: Mittler et al.
The squirming robot that speeds up the insertion of an emergency breathing tube — plus, the 10,000-year-old remains that could be the oldest intentionally preserved mummies
Research Highlight: Soft robot steers itself down the human airway
Research Highlight: Smoke-dried mummies pre-date Egypt’s embalmed bodies
To assess the potential impact of cuts to funding by the Trump administration, Nature trained a machine-learning bot to try and reproduce the NIH’s method of cancelling grants and applied it to science that was successfully funded around ten years ago. This thought experiment shows that highly impactful science and medical research might have been at risk had a similar process been followed a decade ago, revealing the potentially broad-reaching consequences of these actions today.
Nature Index: What research might be lost after the NIH’s cuts? Nature trained a bot to find out
News: Are the Trump team’s actions affecting your research? How to contact Nature
What researchers understand about chatbot-induced psychosis, and the AI designed viruses capable of killing E. coli bacteria.
Nature: Can AI chatbots trigger psychosis? What the science says
Nature: World’s first AI-designed viruses a step towards AI-generated life
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Behind the scenes with Artemis II’s scientists during the historic Moon fly-by
13:40|In this episode:On Monday, reporter Alexandra Witze was in the heart of the Artemis II mission’s science operations. She tells us about the experience and what NASA’s researchers have learnt from the mission so far.Nature: I was with Artemis II’s scientists during the Moon fly-by. Here’s what I sawNature: First photos from Artemis II: see stunning ‘Earthset’ and moreNature: Historic Artemis II Moon fly-by — Nature’s live coverage as it happenedSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: The tongue trick that helps sunbirds suck
13:52|In this episode:00:41 Exosome therapies could deliver drugs to hard to reach placesNature: Eye drops made from pig semen deliver cancer treatment to mice5:08 The impact of parenthood on women’s academic careersNature: Motherhood derails women’s academic careers — these data reveal how and why10:34 The unusual suction that lets Sunbirds drinkScience: These birds suck—literallySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Artemis II is go: humans head to the Moon after half-century absence
15:20|In this podcast we'll talk about NASA's Artemis II launch, which has ushered in a new era of lunar exploration.Nature: Lift off! Artemis II mission sends humans to the Moon — opening a new era of explorationNature: Artemis II mission is about to fly humans to the Moon — here’s the science they’ll doNature: Humanity is heading back to the Moon — why aren’t more scientists thrilled?Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.These scientists chased a jet to learn more about ‘lean-burn’ contrails
24:48|In this episode:00:46 Collecting contrails at 30,000 feetResearch Article: Voigt et al.11:23 Research HighlightsNature: Sunken Soviet nuclear submarine’s radioactive releaseNature: History of ‘forever’ chemicals is written in Antarctic snow13:34 Fakery in scienceApril Fakes DaySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: ‘Zombie cells’ resurrected with new genes
11:01|Nature staff discuss some of the week's top science news.00:18 ‘Zombie cells’ revived with genome transplantNature: ‘Zombie cells’ return from the dead — after a genome transplant05:27 A limit to cloning, in miceNature: Can a mouse be cloned indefinitely? Decades-long experiment has answersSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Why insects aren't huge: a new challenge to a decades-old idea
22:42|00:44 Why insects aren’t massiveResearch Article : Snelling et al.11:39 Research HighlightsNature: Faster ticking of ‘biological clock’ predicts shorter lifespanNature: Mighty mini-magnet is low in cost and light on energy use14:05 CRISPR creates CAR-T cancer therapy inside miceResearch Article: Nyberg et al.News & Views: A gene-editing method generates immunotherapeutic CAR T cells in the bodyNature: CRISPR makes enhanced cancer-fighting immune cells inside miceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Are scientists funny? The evidence is in — and it's no joke
09:52|In this episode:00:22 Exploring how gut microorganisms contribute to ageingNature: Memory loss is fuelled by gut microbes in ageing mice04:30 How good jokes are in short supply during academic conferencesNature: Knock knock, no one’s there. Study finds scientists’ jokes mostly fall flatSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Botanical mystery solved: how plants make a crucial malaria drug
15:55|In this episode:00:46 Piecing together a biochemical puzzleResearch Article : Lombe et al.12:26 Research HighlightsNature: Electric-vehicle batteries toughen up to beat the heatNature: Live parrots were carried across the Andes before the Incas’ rise
Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
10:34|00:26 Why researchers keep using Doom in their researchNature: How the classic computer game Doom became a tool for scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.