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Ancient viral DNA helps human embryos develop
Research suggests that ancient viral-DNA embedded in the human genome is playing a key role in early embryo development. Around 8% of our genome consists of endogenous retrovirus DNA — the remnants of ancient infections, but knowledge of their activity is limited. Now, a team show that these sequences are required for the correct development of lab-derived embryo analogues, and for the switching on of human-specific genes.
Research Article: Fueyo et al.
News and Views: Ancient viral DNA in the human genome shapes early development
Longer whale mothers are more likely to give birth to daughters — plus, how the stink of the corpse flower waxes and wanes to attract pollinators.
Research Highlight: Big mother whales have more daughters than sons
Research Highlight: Corpse flowers waft out stinky compounds as fast as landfills do
Researchers have developed a way to use heat to recharge DNA-based computer circuits, which could help overcome one of the stumbling blocks preventing this technology from being scaled up. Although DNA strands have been used to perform computational tasks for some time, current methods can run out of energy or build up waste products, preventing their continued use. Now, using just heat a team have demonstrated a reuseable neural network based on DNA. They hope that ultimately this could be a step in the development of bigger and more powerful DNA computers that could be used to power targeted clinical therapies.
Research Article: Song & Qian
A one-time gene therapy for Huntington’s disease show promise at slowing the brain disorder’s progression — plus, how mitochondria throw out ‘tainted’ DNA.
Nature: Huntington’s disease treated for first time using gene therapy
Nature: Mitochondria expel tainted DNA — spurring age-related inflammation
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Behind the scenes with Artemis II’s scientists during the historic Moon fly-by
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Briefing Chat: The tongue trick that helps sunbirds suck
13:52|In this episode:00:41 Exosome therapies could deliver drugs to hard to reach placesNature: Eye drops made from pig semen deliver cancer treatment to mice5:08 The impact of parenthood on women’s academic careersNature: Motherhood derails women’s academic careers — these data reveal how and why10:34 The unusual suction that lets Sunbirds drinkScience: These birds suck—literallySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Artemis II is go: humans head to the Moon after half-century absence
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24:48|In this episode:00:46 Collecting contrails at 30,000 feetResearch Article: Voigt et al.11:23 Research HighlightsNature: Sunken Soviet nuclear submarine’s radioactive releaseNature: History of ‘forever’ chemicals is written in Antarctic snow13:34 Fakery in scienceApril Fakes DaySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: ‘Zombie cells’ resurrected with new genes
11:01|Nature staff discuss some of the week's top science news.00:18 ‘Zombie cells’ revived with genome transplantNature: ‘Zombie cells’ return from the dead — after a genome transplant05:27 A limit to cloning, in miceNature: Can a mouse be cloned indefinitely? Decades-long experiment has answersSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Why insects aren't huge: a new challenge to a decades-old idea
22:42|00:44 Why insects aren’t massiveResearch Article : Snelling et al.11:39 Research HighlightsNature: Faster ticking of ‘biological clock’ predicts shorter lifespanNature: Mighty mini-magnet is low in cost and light on energy use14:05 CRISPR creates CAR-T cancer therapy inside miceResearch Article: Nyberg et al.News & Views: A gene-editing method generates immunotherapeutic CAR T cells in the bodyNature: CRISPR makes enhanced cancer-fighting immune cells inside miceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: Are scientists funny? The evidence is in — and it's no joke
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15:55|In this episode:00:46 Piecing together a biochemical puzzleResearch Article : Lombe et al.12:26 Research HighlightsNature: Electric-vehicle batteries toughen up to beat the heatNature: Live parrots were carried across the Andes before the Incas’ rise
Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
10:34|00:26 Why researchers keep using Doom in their researchNature: How the classic computer game Doom became a tool for scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.