Nature Podcast

00:55 Graphene TongueResearchers have developed a graphene ‘tongue’ that uses AI to tell the subtle differences between drinks. Graphene has long been sought after as a chemical sensor, but tiny variations between devices have meant that it couldn’t be used very reliably. The team behind the ‘tongue’ got around this problem by training an AI to tell the difference between similar liquids regardless of variations between graphene devices. They hope that their work shows that it’s possible to use ‘imperfect’ chemical sensors to get accurate readings and that the ‘tongue’ will be able to help detect problems with food.Research Article: Pannone et al.09:22 Research HighlightsA 3D-printed optical microscope that can image biological samples with ultrahigh resolution, and how newly-hatched sea turtles dig their way up to the beach.Research Highlight: A ‘Swiss army knife’ microscope that doesn’t break the bankResearch Highlight: Baby sea turtles ‘swim’ up from buried nests to the open air11:32 How migrating salmon move nutrients and contaminants at a continental scaleStudies of migrating Pacific salmon have revealed that these animals transport thousands of tonnes of nutrients and kilograms of contaminants from the ocean to freshwater ecosystems. It’s been known that as the fish return to their freshwater spawning grounds from the sea they bring with them both nutrients and contaminants, but the impact of each has largely been studied separately. A new study combines datasets to estimate that over 40 years, the levels of nutrients these fish carry have increased at a proportionally higher rate than the contaminants, but the toxins could nevertheless be present at concerning levels to the animals that eat them.Research Article: Brandt et al.News and Views: Salmon’s moveable feast of nutrients with a side order of contaminants23:19 Nobel NewsFlora Graham from the Nature Briefing joins us to talk about the winners of this year’s science Nobel Prizes.News: Medicine Nobel awarded for gene-regulating ‘microRNAs’News: Physics Nobel scooped by machine-learning pioneers News: Chemistry Nobel goes to developers of AlphaFold AI that predicts protein structuresSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

00:46 Physicists spot new types of high-energy radiation in thunderstormsPhysicists have identified new forms of γ-ray radiation created inside thunderclouds, and shown that levels of γ-ray production are much higher on Earth than previously thought.Scientists already knew about two types of γ-ray phenomena in thunderclouds — glows that last as long as a minute and high-intensity flashes that come and go in only a few millionths of a second. Now, researchers have identified that these both occur more frequently than expected, and that previously undetected γ-ray types exist, including flickering flashes that share characteristics of the other two types of radiation.The researchers hope that understanding more about these mysterious phenomena could help explain what initiates lightning, which often follows these γ-ray events.Research Article: Østgaard et al. Research Article: Marisaldi et al. Nature: Mysterious form of high-energy radiation spotted in thunderstorms10:00 Research HighlightsAncient arrowheads reveal that Europe's oldest battle likely featured warriors from far afield, and why the dwarf planet Ceres’s frozen ocean has deep impurities.Research Highlight: Bronze Age clash was Europe’s oldest known interregional battle Research Highlight: A dwarf planet has dirty depths, model suggests12:09 A complete wiring diagram of the fruit fly brainResearchers have published the most complete wiring diagram, or ‘connectome’ of the fruit fly’s brain, which includes nearly 140,000 neurons and 54.5 million connections between nerve cells.The map, made from the brain of a single female fruit fly (Drosophila melanogaster), reveals over 8,400 neuron types in the brain, and has enabled scientists to learn more about the brain and how it controls aspects of fruit fly behaviour.The FlyWire connectome: neuronal wiring diagram of a complete fly brainNature: Largest brain map ever reveals fruit fly's neurons in exquisite detail22:16 Briefing ChatHow researchers created an elusive single-electron bond between carbon atoms, and why bigger chatbots get over-confident when answering questions.Nature: Carbon bond that uses only one electron seen for first time: ‘It will be in the textbooks’Nature: Bigger AI chatbots more inclined to spew nonsense — and people don't always realizeSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

The world's fastest supercomputer, known as Frontier, is located at the Leadership Computing Facility at Oak Ridge National Laboratory in Tennessee. This machine churns through data at record speed, outpacing 100,000 laptops working simultaneously.With nearly 50,000 processors, Frontier was designed to push the bounds of human knowledge. It's being used to create open-source large language models to compete with commercial AI systems, simulate proteins for drug development, help improve aeroplane engine design, and more.This is an audio version of our Feature: A day in the life of the world’s fastest supercomputer

In this episode:00:46 Unravelling why children with Down’s syndrome are at a higher risk of leukaemiaChildren with Down’s syndrome have a 150-fold increased risk of developing leukaemia than those without the condition. Now, an in-depth investigation has revealed that changes to genome structures in fetal liver stem-cells appear to be playing a key role in this increase.Down’s syndrome is characterised by cells having an extra copy of chromosome 21. The team behind this work saw that in liver stem-cells — one of the main places blood is produced in a growing fetus — this extra copy results in changes in how DNA is packaged in a nucleus, opening up areas that are prone to mutation, including those known to be important in leukaemia development.The researchers hope their work will be an important step in understanding and reducing this risk in children with Down’s syndrome.Research Article: Marderstein et al. News and Views: Childhood leukaemia in Down’s syndrome primed by blood-cell bias11:47 Research HighlightsHow taking pints of beer off the table lowers alcohol consumption, and a small lizard’s ‘scuba gear’ helps it stay submerged.Research Highlight: A small fix to cut beer intake: downsize the pintResearch Highlight: This ‘scuba diving’ lizard has a self-made air supply14:12 Briefing ChatHow tiny crustaceans use ‘smell’ to find their home cave, and how atomic bomb X-rays could deflect an asteroid away from a deadly Earth impact.Science: In the dark ocean, these tiny creatures can smell their way homeNature: Scientists successfully ‘nuke asteroid’ — in a lab mock-upSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

In this episode:00:45 The biggest black hole jets ever seenAstronomers have spotted a pair of enormous jets emanating from a supermassive black hole with a combined length of 23 million light years — the biggest ever discovered. Jets are formed when matter is ionized and flung out of a black hole, creating enormous and powerful structures in space. Thought to be unstable, physicists had theorized there was a limit to how large these jets could be, but the new discovery far exceeds this, suggesting there may be more of these monstrous jets yet to be discovered.Research Article: Oei et al. 09:44 Research HighlightsThe knitted fabrics designed to protect wearers from mosquito bites, and the role that islands play in fostering language diversity.Research Highlight: Plagued by mosquitoes? Try some bite-blocking fabricsResearch Highlight: Islands are rich with languages spoken nowhere else12:26 A sustainable, one-step method for alloy productionMaking metal alloys is typically a multi-step process that creates huge amounts of emissions. Now, a team demonstrates a way to create these materials in a single step, which they hope could significantly reduce the environmental burdens associated with their production. In a lab demonstration, they use their technique to create an alloy of nickel and iron called invar — a widely-used material that has a high carbon-footprint. The team show evidence that their method can produce invar to a quality that rivals that of conventional manufacturing, and suggest their technique is scalable to create alloys at an industrial scale.Research article: Wei et al.25:29 Briefing ChatHow AI-predicted protein structures have helped chart the evolution of a group of viruses, and the neurons that cause monkeys to ‘choke’ under pressure.Nature News: Where did viruses come from? AlphaFold and other AIs are finding answersNature News: Why do we crumble under pressure? Science has the answerSubscribe to the Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

In this episode:00:45 What ancient DNA has revealed about Rapa Nui’s pastAncient DNA analysis has further demonstrated that the people of Rapa Nui did not cause their own population collapse, further refuting a controversial but popular claim. Rapa Nui, also known as Easter island, is famous for its giant Moai statues and the contested idea that the people mismanaged their natural resources leading to ‘ecological suicide’. Genomes sequenced from the remains of 15 ancient islanders showed no evidence of a sudden population crash, substantiating other research challenging the collapse idea.Research Article: Moreno-Mayar et al.News and Views: Rapa Nui’s population history rewritten using ancient DNANews article: Famed Pacific island’s population 'crash' debunked by ancient DNA17:03 Research HighlightsThe extinct bat-eating fish that bit off more than they could chew, and how manatee dung shapes an Amazonian ecosystem.Research Highlight: Ancient fish dined on bats — or died tryingResearch Highlight: The Amazon’s gargantuan gardeners: manatees19:29 A macabre parasite of adult fruit fliesDespite being a hugely-studied model organism, it seems that there’s still more to find out about the fruit fly Drosophila melanogaster, as researchers have discovered a new species of parasitoid wasp that infects the species. Unlike other parasitic wasps, this one lays its eggs in adult flies, with the developing larva devouring its host from the inside. The miniscule wasp was discovered by chance in an infected fruit fly collected in a Mississippi backyard and analysis suggests that despite having never been previously identified, it is widespread across parts of North America.Research article: Moore et al.32:04 Briefing ChatHow a dye that helps to give Doritos their orange hue can turn mouse tissues transparent, and an effective way to engage with climate-science sceptics.Nature News: Transparent mice made with light-absorbing dye reveal organs at workNature News: How to change people’s minds about climate change: what the science says