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Gary Heferle: Innovation In Home Mushroom Cultivation
Gary Heferle and his wife Addie run Fresh From The Farm Fungi LLC out of their home and have mastered the art of cultivating dozens of different rare and exotic fungi including Cordyceps Militaris, Lions Mane, Bears Head, Chestnut, Pioppini, Shiitake, and over a dozen more varieties -
Gary breaks down cutting innovations in the mushroom cultivation industry, including his current experiments cultivating wild mushrooms that have thus far largely eluded the grasp of commercial cultivation. We also dive into nascent opportunities for the hemp industry and the mushroom industry to link up and double down on closing the environmental loop together.
Gary was a full-fledged member of the corporatocracy working in a lab environment for a number of years before fully dedicating himself to the mycopreneurial venture that is Fresh From The Farm Fungi, so we’re also going to pick his brain about the how and the why and the when of fully committing oneself to being a mycopreneur.
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2. Andy Sudbrock: Laughter Is Medicine Retreat
40:16||Season 4, Ep. 2Andy Sudbrock of Sacred Path Retreats joins me on the podcast today to discuss our upcoming Laughter Is Medicine psilocybin mushroom retreat in Jamaica that we're co-hosting at the spectacular Coral Cove Wellness Resort March 15-20 with an afterparty March 20-22. This retreat is explicitly focused on fun and joy with the assistance of psilocybin mushrooms and a tropical paradise setting: Stand up comedy performances, kayaking, snorkeling, a visit to a world-renowned cannabis farm next door, live music, beach bonfires, and much more all amplified by locally grown Psilocybe cubensis mushrooms in a legal setting. Learn more about the retreat hereBook your spot at the retreat directly here
1. Ted Anderson: African Rising Initiative
28:13||Season 4, Ep. 1Ted Anderson is the Co-founder of African Rising initiative , a 501(c)(3) non-profit designed to empower African communities through education, sustainable agriculture, women's empowerment, and self-sufficiency skills.We recorded this episode live in Hoima, Uganda at the Eco-Agric Mushroom Training Center as part of the Third Annual African Rising Mushroom Festival in November, 2025. Thanks for listening and please share on your socials and / or leave a review on the podcast streaming platform of your choice.
Soren Shade: How Drugs Become Illegal
01:05:31|Soren Shade is a drug researcher known for producing Hamilton's Pharmacopeia on Vice and as the Founder of Kratom leaf tea company Top Tree Herbs.We discuss the evolution of drug markets and policy with a long-view approach beginning in the 1870's and on through today's rapidly shifting drug legislation frameworks globally. Please rate and review this episode wherever you're listening ( :
Decentralized Funding for Psychedelic Research with PsyDAO
46:49|PsyDAO is a Decentralized Autonomous Community that is funding decentralized psychedelic science and fast-tracking the careers of emergent researchers by investing in their work across multiple early career fellowship projects. Tyler Quigley and Brittney Scott join me today to discuss the function of a DAO, the work they're funding, and how PsyDAO is decoupling psychedelic science and research from limiting patterns that have defined research in the past.
Erik Lomen: Anarchists in the Mushroom Business
54:16|Erik Lomen is the Founder of Maine Cap N' Stem and the host of MycoWizards podcast. He joins us on Mycopreneur Podcast today to discuss the evolution of the company and the mushroom industry in the United States at large while sharing practical insights and intel on running and scaling an independent mycology outfit with years of experience to their name.
Dillan DiNardo: AI In Psychedelic Drug Development
43:44|Dillan DiNardo, Co-Founder and CEO of Mindstate Design Labs, returns to the Mycopreneur Podcast to share updates on the companies progress as a clinical-stage AI neuroengineering platform and drug development outfit. We explore how Mindstate Design is leveraging artificial intelligence in their drug development process, discuss the origins of the company and it's connection to legendary drug chemist Alexander "Sasha" Shulgin, and cover the evolving landscape of psychedelic drug research and where it could all go from here.Please rate and review wherever you're listening ( :
Lee Carroll: Where Mushroom Tradition Meets Science
45:41||Season 3Lee Carroll is the Lead Medical Herbalist at Real Mushrooms and returns to the Mycopreneur Podcast to share updates on his research and journey deeper into the history of traditional mushroom use as well as the modern science to substantiate functional mushroom claims. We discuss mushrooms for longevity, Reishi for heart health, the connection between primates and mushrooms, ways to prevent cognitive decline, and much more.Please rate and review this episode wherever you're listening ( :
Robert Lattig: Healing Herbals & The Kanna Industry
37:01|Robert Lattig of Healing Herbals returns to the Mycopreneur Podcast to discuss the rise of the Kanna supplement market alongside Amanita muscaria mushrooms, Jamaican Dogwood and much more.
James McConchie: Building Haight Street Shroom Shoppe
51:49|James McConchie is the Founder of Haight Street Shroom Shoppe and started cultivating mushrooms years ago to provide access for his wife as she underwent Chemotherapy - today, he stands as one of the most respected and venerable mushroom entrepreneurs in the San Francisco area and beyond. He joins us today to share lessons from 5 years of running the Haight Street Shroom Shoppe, mushroom culture in California's Bay Area and beyond, and his recent research and development into microdosing for dogs alongside Doc Rob silver of Real MushroomsPlease rate and review this episode wherever you're listening ( :