Evolution 2.0

Bryan Trilley had his first round with cancer at age 19, and he has had three new cancers since. He is in his forties with five children under ten, and he is Exhibit A of a proactive individual who takes charge of their own health. He tells his story and describes the information and AI tools he uses to provide a level of custom medical support that no doctor or institution by itself could provide.

Physics always obeys equations. Biology does not. Sometimes... but not always! There is scarcely any formula in biology that is 100% true. In biology, there is no precise definition of life, species, individual, gene, allele, inheritance, intelligence, sentience, function, or fitness.This isn't simply because biology is complex, it's because biology has agency and the ability to make choices. These choices are not an illusion; it's the only reason life can flourish. This simple fact, backed by formal mathematical proofs, has vast implications for the very definition of science itself.In this talk at the American Scientific Affiliation in Boston, Perry Marshall unpacks the vast implications of this.

I met Rev. Prof. Andrew G. Gosler at a dinner at Oxford a few years ago — he's an ornithologist who spent 30 years in the woods studying birds, and he completely lit up the room. He grew up Jewish, ditched religion at his bar mitzvah to go birding, and then decades later, Dawkins' books accidentally pushed him toward Christianity — he was baptized in 2000 and eventually ordained as a priest. Andrew says: "Blue tits don't need to be saved — they're already in heaven. It's only humans that need saving, and we need to be saved from ourselves."

Anthony Hilb lives with asthma and chronic respiratory issues. In May 2025, he experienced a medical crisis that caused him to briefly lose consciousness and have a near-death experience. In this conversation, Anthony shares what he encountered during those crucial minutes and what the experience has meant to him since. We also explore documented accounts from others who have reported similar experiences at the threshold between life and death.

Jay Cross interviews me about my new paper, The Reasonable Ineffectiveness of Mathematics in the Biological Sciences (co-authored with Sy Garte and Stuart Kauffman.) Together we explore why “there are no equal signs in biology,” how this revelation redefines medicine as we know it, and the post-computational, post-permission future of healing—with new hope for people facing serious health challenges. Jay is an accomplished direct response copywriter and researcher with great interest in the THIRD TRANSITION in science, and this conversation opens that up in a big way.

Perry describes a series of life-changing "thin place" experiences that shifted his reality. This was presented to Adam Safron's Sapience group, followed by a guided meditation and a Q&A at the end. A further expansion on these ideas is online at perrymarshall.com/ireland. 

 Sy Garte's book, Beyond Evolution, is written for the person who is trying to reconcile their deep yearnings for meaning and significance with the longstanding scientific dogma that nature has no purpose. Not only is the tide shifting dramatically inside of secular science, the new discoveries are connecting gaps between the many factions and divisions within the religious world.Sy GarteEmail: sygarte@gmail.com [mailto:sygarte@gmail.com]Website: https://sygarte.com/Substack: https://sygarte.substack.com/Pre-order Beyond Evolution on Amazon [https://www.amazon.com/Beyond-Evolution-Discoveries-Science-Point/dp/B0DJY6PY7H]

What happens when researchers from competing scientific worldviews sit down for an honest conversation? In this dialogue, three thinkers—exploring Neo-Darwinism,Third Way evolution, and Intelligent Design—discover unexpected common ground while respecting disagreements. Denis Noble (Oxford University, Third Way evolution, www.thethirdwayofevolution.com), Casey Luskin (Discovery Institute, Intelligent Design, www.evolutionnews.org), and Perry Marshall (Evolution 2.0, bridge-builder, www.evo2.org) engage in the kind of scientific discourse that's increasingly rare: genuine curiosity about opposing viewpoints without the usual academic tribalism.A Third Way evolutionist who challenges both Neo-Darwinian orthodoxy AND Intelligent Design assumptionsAn ID theorist who genuinely appreciates criticisms of mainstream evolutionary theoryDiscoveries of shared ground where opponents thought none existedHonest wrestling with profound questions about consciousness, agency, and the nature of life itselfThis isn't just another evolution debate. It's a case study in how scientists engage across ideological divides to advance understanding. The most profound insights often emerge not from echo chambers, but from healthy tension between opposing ideas. "We don't substitute any certainties whatsoever... let it evolve. Let us find out, let us, for God's sake, be open to what it might be that we discover."Denis Noble Transcript: https://evo2.org/wp-content/uploads/2025/07/Bridging-Evolution-A-Conversation-Between-Intelligent-Design-and-Third-Way-transcript.pdf

Andrew Briggs started to write the book Human Flourishing just before COVID and then the world went mad. Since then, the world has gotten even madder and many people are clutching their smartphones, wringing their hands, managing their anxiety, or merely existing. What does it mean to flourish and what do people, relationships, and professions look like and feel like when they flourish? In this book, authors Andrew Briggs and Michael J. Reiss and painter Roger Wagner weave together a beautiful picture of the material and immaterial, the concrete and the spiritual. Included here is a reproduction of Roger Wagner's painting It Keeps Me Seeking. The original painting hangs in The Auckland Project Faith Museum: https://aucklandproject.org/attraction/faith-museum/