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Babbage from The Economist

Babbage: The gene-therapy revolution

Gene therapies border on the miraculous, transforming lives in a single shot. The treatments offer hope to millions around the world who live with genetic diseases, and could also help the fight against cancer and HIV. This year, four new gene therapies were approved—and there are thousands more clinical trials under way. But the path from miracles of science to miracles of medicine will not be easy. The Economist’s Natasha Loder explains the safety concerns and market challenges that must be overcome to make the genetic revolution possible. Alok Jha hosts.


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    Scientists are still uncovering the myriad ways in which the gut microbiome affects human health. An out-of-kilter ecosystem of microbes can cause diseases of the gastrointestinal tract. But it has also been linked to obesity and conditions such as liver disease and Alzheimer’s. Understanding those connections opens up a new type of medicine. Is the era of microbiome treatments about to arrive?Host: Gilead Amit, The Economist’s science correspondent. Contributors: Désirée Prossomariti and Simon Goldenberg of St Thomas’ Hospital in London; Glenn Gibson of the University of Reading; Debbie Shawcross of King’s College London; Matt Cheng, boss of Kanvas Biosciences; Natasha Loder, The Economist's health editor. Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
  • Babbage: How to save coral reefs

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  • Babbage: The hunt for new worlds

    41:08
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  • Babbage: The science that built the AI revolution—part four

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    What made AI models generative? In 2022, it seemed as though the much-anticipated AI revolution had finally arrived. Large language models swept the globe, and deepfakes were becoming ever more pervasive. Underneath it all were old algorithms that had been taught some new tricks. Suddenly, artificial intelligence seemed to have the skill of creativity.  Generative AI had arrived and promised to transform…everything.This is the final episode in a four-part series on the evolution of modern generative AI. What were the scientific and technological developments that took the very first, clunky artificial neurons and ended up with the astonishingly powerful large language models that power apps such as ChatGPT?Host: Alok Jha, The Economist’s science and technology editor. Contributors: Lindsay Bartholomew of the MIT Museum; Yoshua Bengio of the University of Montréal; Fei-Fei Li of Stanford University; Robert Ajemian and Greta Tuckute of MIT; Kyle Mahowald of the University of Texas at Austin; Daniel Glaser of London’s Institute of Philosophy; Abby Bertics, The Economist’s science correspondent. On Thursday April 4th, we’re hosting a live event where we’ll answer as many of your questions on AI as possible, following this Babbage series. If you’re a subscriber, you can submit your question and find out more at economist.com/aievent. Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
  • Babbage picks: SpaceX’s Starship reaches orbit

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  • Babbage: The science that built the AI revolution—part two

    42:33
    How do machines learn? Learning is fundamental to artificial intelligence. It’s how computers can recognise speech or identify objects in images. But how can networks of artificial neurons be deployed to find patterns in data, and what is the mathematics that makes it all possible?This is the second episode in a four-part series on the evolution of modern generative AI. What were the scientific and technological developments that took the very first, clunky artificial neurons and ended up with the astonishingly powerful large language models that power apps such as ChatGPT?Host: Alok Jha, The Economist’s science and technology editor. Contributors: Pulkit Agrawal and Gabe Margolis of MIT; Daniel Glaser, a neuroscientist at London’s Institute of Philosophy; Melanie Mitchell of the Santa Fe Institute; Anil Ananthaswamy, author of “Why Machines Learn”.On Thursday April 4th, we’re hosting a live event where we’ll answer as many of your questions on AI as possible, following this Babbage series. If you’re a subscriber, you can submit your question and find out more at economist.com/aievent. Get a world of insights for 50% off—subscribe to Economist Podcasts+If you’re already a subscriber to The Economist, you’ll have full access to all our shows as part of your subscription. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
  • Babbage picks: How smart are “smart-drugs”?

    04:24
    An article from The Economist read aloud. Our business section reports that brain-boosting substances are all the rage but their utility is debatable.
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    42:57
    What is intelligence? In the middle of the 20th century, the inner workings of the human brain inspired computer scientists to build the first “thinking machines”. But how does human intelligence actually relate to the artificial kind?This is the first episode in a four-part series on the evolution of modern generative AI. What were the scientific and technological developments that took the very first, clunky artificial neurons and ended up with the astonishingly powerful large language models that power apps such as ChatGPT?Host: Alok Jha, The Economist’s science and technology editor. Contributors: Ainslie Johnstone, The Economist’s data journalist and science correspondent; Dawood Dassu and Steve Garratt of UK Biobank; Daniel Glaser, a neuroscientist at London’s Institute of Philosophy; Daniela Rus, director of MIT’s Computer Science and Artificial Intelligence Laboratory; Yoshua Bengio of the University of Montréal, who is known as one of the “godfathers” of modern AI.On Thursday April 4th, we’re hosting a live event where we’ll answer as many of your questions on AI as possible, following this Babbage series. If you’re a subscriber, you can submit your question and find out more at economist.com/aievent. Get a world of insights for 50% off—subscribe to Economist Podcasts+If you’re already a subscriber to The Economist, you’ll have full access to all our shows as part of your subscription. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.