Babbage from The Economist

Proteins are the molecular machines that make life work. Each one in your body has a specific task—some become muscles, bones and skin. Others carry oxygen in the blood or get used as hormones or antibodies. Yet more become enzymes, helping to catalyse chemical reactions inside our bodies. Given proteins can do so many things, what if scientists could design bespoke versions to order? Novel proteins, never seen before in nature, could make biofuels, say, or clean up pollution or create new ways to harvest power from sunlight. David Baker, a biochemist and recent Nobel laureate in chemistry, has been working on that challenge since the 1980s. Now, powered by artificial intelligence and inspired by living cells, he is leading scientists around the world in inventing a whole new molecular world. Host: Alok Jha, The Economist’s science and technology editor. Contributors: David Baker of the University of Washington; and The Economist’s Geoff Carr and Emilie Steinmark. Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

The Vera Rubin Observatory is about to start a decade-long survey of the night sky. In the process, it will generate hundreds of petabytes of astronomical data. Hidden within that firehose of information will be clues about some of the universe’s deepest mysteries—from dark matter and dark energy to the evolution of galaxies. To help scientists unlock those new celestial tales, the Rubin Observatory's team had to invent a bespoke way to organise, analyse and share the data. That technology, which will usher in a new, automated era for astronomy, may be one of the observatory’s most important and enduring legacies. In the second of two episodes, we visit the Rubin Observatory, 2,700m high in the Chilean Andes, to uncover how the telescope’s data travel from the summit to astronomers’ desks around the world. Listen to the first episode here. Host: Alok Jha, The Economist’s science and technology editor. Contributors: William O’Mullane, Yusra AlSayyad and Leanne Guy. Thanks to everyone we spoke to at the Vera Rubin Observatory, including Alysha Shugart, Guillem Megias, Marina Pavlovic and Kevin Fanning.You can see and explore the first images taken by the Vera Rubin Observatory on the SkyViewer platform.For more on the scientific questions that the Vera Rubin Observatory is seeking to answer, listen to our “cosmology in crisis” series. Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

This week, the first images were released from the world’s most powerful digital camera, nestled in the heart of a brand new telescope at the Vera Rubin Observatory. From October, the 3,200 megapixel camera will begin to create a decade-long film of the entire night sky, and promise to unlock some of the deepest mysteries of our universe—from how galaxies form and evolve to the nature of dark matter and dark energy. In the first of two episodes, we visit the Rubin Observatory, 2,700m high in the Chilean Andes to hear what this new facility can do and learn about the monumental engineering required to build it.Host: Alok Jha, The Economist’s science and technology editor. Contributors: Victor Krabbendam, Stephanie Deppe and Leanne Guy of the Vera Rubin Observatory. Listen to our second episode from the Vera Rubin Observatory—uncovering how the telescope’s data get from the summit to astronomers’ desks around the world—here, or by searching for “astronomy enters its digital age” on your podcast app. Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

The evolution of drone technology in warzones, such as Ukraine, is showing no signs of slowing. But as drones have become more capable, the traditional ways to bring them down—such as electronic jamming or physically firing shots at them—are becoming less effective. Engineers have therefore had to get creative. Several companies are dreaming up devices that emit microwave radiation with the aim of disabling the electronics of drones. Could they really protect people from the threats swarming in the skies above?Host: Alok Jha, The Economist’s science and technology editor. Contributors: Thomas Withington of RUSI; Andy Lowery of Epirus; The Economist’s Benjamin Sutherland. For more on Ukraine’s drone war, listen to “The Weekend Intelligence: Inside Operation Spider Web”.Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

Supermarkets and social-media feeds are bursting with “immune-boosting” products that promise to make you better able to fend off infections. But can orange juice really fight a cold? And will a fancy yoghurt help your microbiome prevent illness? Enter a myth-busting immunologist who helps you to ignore the noise and to think critically about your immune health. Alok Jha, The Economist’s science and technology editor, speaks with Daniel Davis, a professor at Imperial College London and the author of a new guide to immune health, “Self Defence”.Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

The large language models underpinning generative AI have tremendous potential to wrangle messy medical data, chat with patients about their personal health, make diagnoses, and even suggest medications and make appointments. But how to ensure that data are kept private and the advice is trustworthy? We meet some of the researchers trying to develop the long-touted doctor in your pocket.Host: Alok Jha, The Economist’s science and technology editor, with Natasha Loder, our health editor. Contributors: Claire Novorol of ADA Health; Adam Rodman and Jason Gusdorf of Harvard Medical School and the Beth Israel Deaconess Medical Centre.For more on this topic, listen to our two-part series on AI in health care, published in May 2024. Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

Across America scientists are reeling as they are hit with wave after wave of grant terminations and funding freezes. Federal science agencies have fired thousands of staff. And President Trump has declared war on the country’s leading universities. The administration says it seeks to usher in a “Golden Age” of science and innovation. Our reporting suggests that it will do the opposite.Host: Alok Jha, The Economist’s science and technology editor, with science correspondent Emilie Steinmark. Contributors: Don Ingber of Harvard University; Amy Nunn of Brown University; Hannah Cooper of Emory University; Brigitte Seim of the University of Minnesota; Jane Carlton of Johns Hopkins University.Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

The Metre Convention is a treaty that codified the measurement of the metre and the kilogram. Signed on May 20th 1875 in Paris, it facilitated trade and underpinned the development of new technology. Accurate measurements are essential for innovation, but the way scientists perform those measurements has changed over time. Now, 150 years since the treaty was first signed, how are scientists improving measurement standards?Hosts: The Economist’s Alok Jha and Gilead Amit. Contributors: JT Janssen, Andrew Lewis and Anne Curtis at Britain’s National Physical Laboratory. Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

In the 1980s Richard Cytowic, a neurologist, came across a patient whose senses seemed to blur into one another. His research into this strange condition defined the modern understanding of what would come to be known as synesthesia. In his latest work he’s been taking on the digital age. His new book considers how humans’ slow-to-evolve brains are at odds with an ever-changing technological environment. As the world gets relentlessly more digital, Professor Cytowic considers the impact of all that information on our attention spans, learning, and even the ability to form human connections.Hosts: Alok Jha, The Economist’s science and technology editor. Contributor: Richard Cytowic, professor of neurology at George Washington University and the author of “Your Stone Age Brain in the Screen Age”.Transcripts of our podcasts are available via economist.com/podcasts.Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+.For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.