The Fundamentals

On today’s The Fundamentals is Dr. Brummett, Professor at the University of Michigan where he serves as the Senior Associate Chair for Research in the Department of Anesthesiology. He has more than 280 publications, including articles in top journals such as JAMA, JAMA Surgery, Anesthesiology, and Annals of Surgery. He is the Co-Director of the Opioid Prescribing Engagement Network or OPEN at the University of Michigan, which aims to apply a preventative approach to the opioid epidemic in the US through appropriate prescribing after surgery, dentistry and emergency medicine. Moreover, he is the Co-Director of the cross-campus Opioid Research Institute, which was launched in the spring of 2023. He leads multiple NIH grants studying these concepts and receives funding from the Michigan Department of Health and Human Services, SAMHSA, CDC, and multiple foundations.You can learn more about Dr. Brummett here, and you can follow Dr. Brummett @drchadb and the department of anesthesiology @UMichAnesthesia on X.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:https://www.michiganmedicine.org/health-lab/feeling-hunger-itself-may-slow-aging-flieshttps://www.michiganmedicine.org/health-lab/different-pain-types-multiple-sclerosis-can-cause-difficulty-staying-activeLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts. 

Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program.You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, and Michigan Neurscience Institute @UM_MNI on X.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:https://www.michiganmedicine.org/health-lab/gene-therapy-brain-tumor-shows-promising-early-results-humanshttps://www.michiganmedicine.org/health-lab/two-genes-linked-autism-implicated-brain-cell-connectivityLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Dr. Jody Platt. She is an Associate Professor of Learning Health Sciences at the University of Michigan Medical School. Trained in medical sociology and health policy, her research focuses on issues at the intersection of informatics and ethics. She is interested in understanding what makes data-driven health trusted, and the pathways for earning, achieving, and sustaining trust across stakeholders. Dr. Platt is the Academy Health and ABIM Foundation Senior Scholar in Residence advising on issues of measuring and building trust.You can learn more about Dr. Platt here, and you can follow Dr. Platt @jeplatt and U-M Learning Health Sciences @umichDLHS on X.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:https://www.michiganmedicine.org/health-lab/clinicians-could-be-fooled-biased-ai-despite-explanationshttps://www.michiganmedicine.org/health-lab/can-ai-help-hospitals-spot-patients-need-extra-non-medical-assistanceLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Today on The Fundamentals, our guest Dr. Martin Myers, Director of the U-M Elizabeth Weiser Caswell Diabetes Institute, discusses diabetes research in the context of Ozempic, Wegovy, and other drugs that are changing how people think about weight loss.You can learn more about Dr. Myers here, and you can follow the department of molecular and integrative physiology @UMPhysiology on X.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:https://www.michiganmedicine.org/health-lab/diabetes-linked-functional-and-structural-brain-changes-through-mrihttps://www.michiganmedicine.org/health-lab/device-makes-lot-senseLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Today on The Fundamentals, our guest is Dr. Michelle Kahlenberg, an Associate Professor of Internal Medicine and Dermatology, the Giles Bole and Dorothy Mulkey Research Professor of Rheumatology and the Vice Chair for Basic and Translational Research in Internal Medicine.Her clinical work is centered on the care of patients with lupus, including those with refractory skin disease. In addition to running her lab, she's an active member of the Immunology Training Program and has received national recognition for her research.You can learn more about Dr. Kahlenberg here, and you can follow the Kahlenberg Lab @Kahlenberglab and the department of internal medicine @UMIntMed on X.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:https://www.michiganmedicine.org/health-lab/obesity-leads-complex-inflammatory-response-inside-fat-tissuehttps://www.michiganmedicine.org/health-lab/could-ginger-help-treat-autoimmune-disease-symptomsLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Today on The Fundamentals, our guest is Dr. Julie Lumeng, the associate dean for research at the University of Michigan Medical School, executive director of the Michigan Institute for Clinical and Health Research, and the associate vice president for Clinical and Human Subjects Research for the university. She's also a professor in the departments of pediatrics and nutritional sciences, providing leadership on the strategic vision of the medical school's office of research, as well as running her own research lab focused on applying emerging science in child development and behavior to the prevention and treatment of childhood obesity. You can learn more about Dr. Lumeng here, and you can follow the Dr. Lumeng @JulieLumeng and the Michigan Institute for Clinical and Health Research (MICHR) @UM_MICHR on Twitter.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:Mapping the brain stem’s control of eating could lead to better treatments for obesityAn atlas of neuronal circuits could help predict targets for medications to control appetiteThe feeling of hunger itself may slow aging in fliesResearch examines changes in the brain that prompt the drive to seek foodLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Today on The Fundamentals, our guest is Dr. Pooja Lagisetty, an assistant professor of internal medicine and a research scientist at the Center for Clinical Management and Research at the Ann Arbor VA. Her research focuses on addressing access barriers and developing multidisciplinary interventions to better treat chronic pain and addiction across general medical settings. Her research has been influential in understanding stigma and disparities for individuals with pain and addiction.You can learn more about Dr. Lagisetty here, and you can follow the Dr. Lagisetty @PoojaLagisetty, the U-M Institute for Healthcare Policy & Innovation @UM_ihpi and the U-M Department of Internal Medicine @UMIntMed on Twitter.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:How one state beat national surgery opioid trendsPrescribing guidelines accelerated Michigan’s progress over the rest of the nation, study showsZip code and hospital quality may both affect the risk of dying after surgeryPeople who lived in under-resourced neighborhoods and underwent operations at lower-quality hospitals were more likely to die within 30 daysLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.

Today on The Fundamentals, our guest is Dr. Jessica Anand, a research assistant professor in the Department of Pharmacology at the University of Michigan Medical School, and a co-chair of the Pharmacology's Diversity, Equity and Inclusion Committee. Her work focuses on developing new molecules to treat different medical needs, like pain with reduced addiction risk, overdose, and potentially mood problems like anxiety and depression. Currently, the main thrust of her research is developing new overdose medications. You can learn more about the work Dr. Anand's lab is doing by visiting their website, and you can follow the University of Michigan Department of Pharmacology @UMichPharmacology.You can learn more about The Fundamentals on our website.A transcript of this episode can be found here.Find out more about the research stories mentioned at the top of the show at the links below:Molecule known to slow inflammation linked to scleroderma, could be treatment targetA variation of the molecule can contribute to fibrosis and sclerodermaDid FDA regulation reduce high rates of opioid-acetaminophen overdoses?Hepatologists examine data around a 2011 FDA drug mandateLearn more about other exciting research happening at the University of Michigan, by checking out Health Lab, Michigan Medicine's daily online publication featuring news and stories about the future of healthcare.The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Google Podcasts, Stitcher or wherever you listen to podcasts.