The Doctor's Farmacy with Mark Hyman, M.D.
Reversing Chronic Disease And Aging By Fixing Insulin Resistance with Dr. Ben Bikman
We’re up against an epidemic of chronic metabolic diseases. One thing they all have in common is a component of insulin dysregulation. Take that into account with the fact that 90% of people who have insulin resistance are going to the doctor and remaining undiagnosed. Why then, are we testing everything but insulin? Today, I take a deep dive into the topic of insulin resistance and metabolic health with Dr. Ben Bikman.
Dr. Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Backed by years of research, Dr. Bikman’s mission is to help the world appreciate the prevalence and relevance of insulin resistance. He is the author of the book, Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing pre-diabetes, improving brain function, shedding fat, and preventing diabetes. Dr. Bikman has a Doctor of Philosophy in Bioenergetics from East Carolina University, and completed a postdoctoral fellowship in metabolic disorders with the Duke-National University of Singapore Medical School.
This episode is brought to you by Rupa Health, BiOptimizers, and HigherDOSE.
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Here are more of the details from our interview (audio version / Apple Subscriber version):
- The common driver of metabolic syndrome and chronic disease (5:10 / 1:30)
- What is insulin resistance and why is it so underdiagnosed? (7:57 / 5:08)
- How insulin resistance affects the liver, sex hormones, weight gain, aging, and the brain (15:36 / 12:45)
- Differences in how high-carb and low-carb diets affect metabolism (30:11 / 24:55)
- Three primary causes of insulin resistance (47:52 / 42:39)
- Fat, saturated fats, and insulin resistance (50:58 / 45:46)
- How to know if insulin resistance is a problem for you (1:02:32 / 56:50)
- Ethnic disparities in metabolic predisposition (1:09:18 / 57:11)
- Top things you can do to prevent and reverse the effects of insulin resistance (1:13:07 / 1:03:54)
- Insulin’s role in mTOR, a regulator of aging (1:31:17 / 1:26:05)
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820. Exclusive Dr. Hyman+ Functional Medicine Deep Dive: Endothelial Health21:30Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on endothelial health with Dr. Michael Twyman.Learn more about Dr. Twyman at drtwyman.com and follow him on Instagram @drtwymanWant to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of:- Ad-Free Doctor’s Farmacy Podcast episodes- Exclusive monthly Functional Medicine Deep Dives- Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at firstname.lastname@example.org with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast only includes Dr. Hyman+ in audio content.
819. What Standard Cholesterol Testing Isn't Telling You01:06:16This episode is brought to you by Rupa University, AG1, and Pendulum. Dietary cholesterol from saturated fat is often thought to be the cause of high LDL cholesterol and blocked arteries. But we now know from updated research that it’s much more complicated than that. Standard cholesterol testing is outdated because it doesn’t check for particle size and particle number, information that is needed to tell what’s really going on with your cholesterol. Statins are often prescribed to lower LDL cholesterol, but often do not address the root of the problem and can cause very uncomfortable side effects.In today’s episode, I talk with Drs. Elizabeth Boham, Ronald Krauss, and Aseem Malhotra about the true role of cholesterol and what is really behind heart disease.Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing.Dr. Ronald Krauss is a Senior Scientist at Children’s Hospital Oakland Research Institute, a Professor of Medicine at UCSF, and an Adjunct Professor of Nutritional Sciences at UC Berkeley. Dr. Krauss’s research aims to understand how to best prevent cardiovascular disease through early detection and management of its major risk factors: most notably, elevated levels of blood cholesterol and lipoproteins. He has published more than 450 research articles and reviews on metabolic, genetic, dietary, and drug effects on plasma lipoproteins and the risk of coronary artery disease, with more than 100,000 citations of this work.Dr. Aseem Malhotra is an NHS-trained consultant cardiologist and visiting Professor of Evidence-Based Medicine at the Bahiana School of Medicine and Public Health in Salvador, Brazil. He is a founding member of Action on Sugar. In 2015, he became the youngest member to be appointed to the board of trustees of UK health charity The King's Fund. He is a pioneer of the lifestyle medicine movement in the UK and in 2018 was ranked by software company Onalytica as the number one doctor in the world influencing obesity thinking.This episode is brought to you by Rupa University, AG1, and Pendulum.Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniversity.com.Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get 10 FREE travel packs with your first order.Pendulum is offering listeners 20% off their first month’s subscription of Akkermansia for gut health. Visit PendulumLife.com and use code HYMAN.Full-length episodes of these interviews can be found here:Dr. Elizabeth BohamDr. Ronald KraussDr. Aseem Malhotra
818. 14 "Foods" To Avoid For Better Health32:58This episode is brought to you by ButcherBox and AG1.Food is literally the most powerful medicine we have available to control our health. When we choose to eat quality foods, we gain a whole host of benefits. Our body gets the nutrients it actually needs to function well. We get more energy, our mood improves, we avoid a long list of adverse health effects, and we will overall just feel better. Yet, it can be surprisingly hard to know what to eat and what to avoid, especially with all of the overly processed, chemical-laden “food” in stores and restaurants.In today’s episode of my series I’m calling Health Bites, I walk you through what foods and food ingredients are most damaging to your health.This episode is brought to you by ButcherBox and AG1.For new members of ButcherBox, you can receive New York Strip steaks for a year PLUS $20 off your first order. Go to Butcherbox.com/farmacy and use code FARMACY.Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase.Here are more details from the episode (audio version / Apple Subscriber version):What is ultra-processed food? (5:26 / 3:08)“Good” vs. “bad” processed foods (6:48 / 4:30)14 “foods” to avoid for better health (11:24 / 9:06)
817. Brain Fitness: Reversing Cognitive Decline And Improving Brain Function with Dr. Majid Fotuhi01:13:25This episode is brought to you by Rupa Health, Essentia, Cozy Earth, and AirDoctor.It’s never too early to start protecting your brain, and with more than 6 million Americans living with Alzheimer's—projected to rise to nearly 13 million by 2050—this is something we should all contemplate more often.On today’s episode of The Doctor’s Farmacy, I’m excited to talk to Dr. Majid Fotuhi about the top actions we can take to prevent cognitive decline and optimize brain function.Dr. Majid Fotuhi is a neurologist with expertise in the fields of memory, concussion, and successful aging. Through his 30 years of teaching, clinical work, and neuroscience research at Harvard Medical School and Johns Hopkins, Dr. Fotuhi has developed a multidisciplinary program for helping people of all ages improve their memory and attention. His innovative Brain Fitness Program addresses lifestyle factors and cognitive stimulation, and he has published the successful results of this program in several scientific journals and three books, including Boost Your Brain: The New Art and Science Behind Enhanced Brain Performance. Dr. Fotuhi received his doctorate degree in neuroscience from Johns Hopkins University in 1992 and his Medical Degree from Harvard Medical School in 1997. He serves as an adjunct professor at George Washington University.This episode is brought to you by Rupa Health, Essentia, Cozy Earth, and AirDoctor.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free live demo with a Q&A or create an account at RupaHealth.com today.Receive an extra $100 off your mattress purchase on top of Essentia’s Huge Black Friday Sale! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DRHYMAN.Right now, if you go to drhyman.com/filter you can get the AirDoctor filter for $349. That’s $280 off the normal price.Here are more details from our interview (audio version / Apple Subscriber version):The evolution of Dr. Fotuhi’s understanding of memory and brain health (7:34 / 5:41)Why Dr. Fotuhi started his own brain center (14:10 / 12:17)Incredible science to slow and prevent memory loss (19:07 / 17:14)The myth of diagnosis (23:03 / 21:10)Four ways to support the brain (30:03 / 26:10) The connection between belly size and brain size (31:36 / 27:43)Common culprits of poor brain function (36:29 / 32:36Reactions of Dr. Fotuhi’s colleagues to his work (47:07 / 43:14)Lifestyle practices for a healthy brain (54:17 / 50:24)Modifiable risk factors for brain dysfunction (1:00:14 / 56:24)Learn more at Drfotuhi.com and try the Brain Portfolio/Brain Fitness Calculator.
816. Exclusive Dr. Hyman+ Ask A Doctor: Arthritis, Supporting Children’s Immune Systems, And More18:13Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask A Doctor Anything episode with Dr. Elizabeth Boham.Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of:- Ad-Free Doctor’s Farmacy Podcast episodes- Exclusive monthly Functional Medicine Deep Dives- Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at email@example.com with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.
815. How To Balance Women's Hormones With Lifestyle And Diet55:28This episode is brought to you by Rupa Health, Bioptimizers, and Paleovalley. Contrary to popular belief, women cannot follow the same health and fitness protocols as men and expect the same results. Unlike men, women in their reproductive years have specific hormonal considerations, and their rise and fall throughout the month impact everything from energy to focus, mood, metabolism, and the ability to adapt to good-for-you stressors like exercise or fasting. Meanwhile, perimenopause and menopause pose a whole other list of considerations to keep women feeling well.In today’s episode, I talk with Dr. Mindy Pelz and Dr. Sara Gottfried about why we need to prioritize teaching women about their hormones.Dr. Mindy Pelz is a renowned holistic health expert and one of the leading voices in educating women about their hormonal health. She has empowered hundreds of thousands of people around the world to tap into their bodies' innate healing abilities through her “5-Step Approach,” which uses fasting, personalized nutrition, stress management, chemical detoxification, and lifestyle changes to optimize health and slow the aging process.Dr. Sara Gottfried is a board-certified physician who graduated from Harvard and MIT. She practices evidence-based integrative, precision, and Functional Medicine. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University, and Director of Precision Medicine at the Marcus Institute of Integrative Health. Her three New York Times bestselling books include: The Hormone Cure, The Hormone Reset Diet, and Younger. Her latest book is called Women, Food, and Hormones.This episode is brought to you by Rupa Health, Bioptimizers, and Paleovalley.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free live demo with a Q&A or create an account at RupaHealth.com today.During the entire month of November, Bioptimizers is offering their biggest discount AND giving away amazing gifts with purchases. Just go to bioptimizers.com/hyman using code hyman10.Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal.Full-length episodes of these interviews can be found here:Dr. Mindy PelzDr. Mark HymanDr. Sara Gottfried
814. Why Eating Grains Can Drive Obesity, Heart Disease, Autoimmune Issues, And More27:37This episode is brought to you by Mitopure and LMNT.For nearly all of our history, humans consumed no grains, and our bodies are designed to work very well without them. Today, however, grain-based foods are by far the number one source of calories in the American diet. While whole grains can be a great source of vitamins, minerals, and fiber, the toxic amounts we eat contribute to obesity, diabetes, heart disease, cancer, and dementia. Plus, most of the grains we eat—even whole wheat—are turned into flour products which have a higher glycemic index than table sugar.In today’s episode of my series I’m calling Health Bites, I talk about why grains are such a contentious food, how to tackle the pros and cons of whether it belongs in your diet, and which grains are actually okay to eat. This episode is brought to you by Mitopure and LMNT.Support the growth of new, healthy mitochondria and get 10% off Mitopure. Head to timelinenutrition.com/drmark and use code DRMARK at checkout.Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/hyman today.Here are more details from our interview (audio version / Apple Subscriber version):You don’t have to eat grains to be healthy (8:40 / 5:41)“Whole grain” is a marketing term (10:31 / 7:32)Why starch and sugar are essentially the same thing (11:22 / 8:23)You’re not eating the same grains your grandparents ate (11:58 / 8:59)Is oatmeal good for you? (14:22 / 11:23)Should everyone avoid gluten? (15:36 / 12:37)Not all grains are bad (20:02 / 17:03)Do we really have to give up bread? (21:09 / 18:10)What types of grains are okay and what should be avoided? (23:20 / 20:21)Who should avoid grains altogether? (24:59 / 22:00)
813. The Science Of Hypnosis: A Simple Tool for Treating Stress, Anxiety, Insomnia and Disease with Dr. David Spiegel01:09:49This episode is brought to you by Rupa Health, Bioptimizers, Joovv, and Essentia.When you hear the term “hypnosis,” what immediately comes to mind? Is it a clock-swinging magician or a comedy hypnosis show? What most people don’t know about hypnotherapy is that it’s actually an accredited science with tremendous healing power. On today’s episode of The Doctor’s Farmacy, Dr. David Spiegel, the world’s leading researcher and clinician in the field, is here to help us better understand the scientific power of hypnosis. Dr. David Spiegel is the Willson Professor and Associate Chair of Psychiatry & Behavioral Sciences, Director of the Center on Stress and Health, and Medical Director of the Center for Integrative Medicine at Stanford University School of Medicine, where he has been a member of the academic faculty since 1975, and was Chair of the Stanford University Faculty Senate from 2010-2011. Educated at Harvard and Yale before coming to Stanford, he has written thirteen books, 404 scientific journal articles, and 170 book chapters. He is also the Co-Founder and Chief Scientific Officer of the clinically-backed self-hypnosis app, Reveri. This episode is brought to you by Rupa Health, Bioptimizers, Joovv, and Essentia.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.During the entire month of November, Bioptimizers is offering their biggest discount AND amazing gifts with purchase. Just go to bioptimizers.com/hyman with code hyman10.Visit Joovv.com/FARMACY to take advantage of these unbeatable Black Friday deals. Don't miss out on this limited-time offer! Sale ends 11/27.Receive an extra $100 off your mattress purchase, on top of Essentia’s huge Black Friday sale! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.Here are more details from our interview (audio version / Apple Subscriber version):Dr. Spiegel’s entry into hypnosis (4:57 / 2:33)What is hypnosis? (10:31 / 8:06)The history of hypnosis (12:42 / 10:18)How hypnosis works in the brain (18:17 / 15:53)Is everyone hypnotizable? (26:39 / 21:44)Hypnosis for pain control and insomnia (31:16 / 26:22)Hypnosis for stress management, trauma, and emotional health (39:26 / 34:31)Clinical vs self-hypnosis (45:21 / 40:27)The difference between hypnosis, meditation, and EMDR (54:31 / 49:36)Join the Reveri Community, learn about a discount and the scholarship program Reveri for Good, and explore Hypnosis for Habit Control.Learn more about Dr. Spiegel’s work here.
812. How The Ketogenic Diet Supports Metabolism, Cancer Therapy, And Mental Health01:16:21This episode is brought to you by Rupa Health, AG1, and Paleovalley. While the ketogenic diet is often thought of as a diet to help people lose weight, it has a much broader application with therapeutic benefits that help to reset metabolism and restore mitochondrial function. Researchers have found that a ketogenic diet can be a potent tool in cancer treatment as well as in neurodegenerative disorders and mental illness.In today’s episode, I talk with Mark Sisson, Dr. Sarah Hallberg, Dr. Christopher Palmer, and Dr. Patrick Hanaway about how a ketogenic diet can be used as a treatment for serious health conditions.Mark Sisson is the founder of the popular daily health blog Mark’s Daily Apple, godfather to the Primal food and lifestyle movement, and the New York Times bestselling author of The Keto Reset Diet. His latest book is Keto for Life, where he discusses how he combines the keto diet with a Primal lifestyle for optimal health and longevity.The late Dr. Sarah Hallberg was a medical director at Virta Health, a fellow of the Aspen Institute’s Health Innovator Fellowship, and a member of the Aspen Global Leadership Network. She was also the Medical Director and founder of the Medically Supervised Weight Loss Program at Indiana University Health Arnett and an adjunct professor of clinical medicine at the Indiana University School of Medicine.Dr. Christopher Palmer is a psychiatrist and researcher working at the interface of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses.Dr. Patrick Hanaway is a board-certified family physician and trained at Washington University. After 10 years as Chief Medical Officer at Genova Diagnostics, Dr. Hanaway became the Chief Medical Education Officer for the Institute for Functional Medicine. In 2014, Dr. Hanaway was the founding Medical Director of the Cleveland Clinic Center for Functional Medicine.This episode is brought to you by Rupa Health, AG1, and Paleovalley.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase.Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to take advantage of this deal.Full-length episodes of these interviews can be found here:Mark SissonDr. Sarah HallbergDr. Christopher PalmerDr. Patrick Hanaway