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Saving Lives In Slow Motion
Type 2 Diabetes - it's rise and rise
Type 2 Diabetes has doubled in the last 15 years in the UK. It is associated with potentially serious complications from kidney failure to blindness but there is a process called insulin resistance that occurs prior to its onset.
In this episode I look at the development, prevention and management of this condition.
Diabetes stats for the UK: https://www.diabetes.org.uk/about_us/news/number-people-living-diabetes-uk-tops-5-million-first-time
Diabetes prevention strategies: https://evidence.nihr.ac.uk/alert/diabetes-prevention-programme-providers-need-more-consistency-flexibility-equality-of-access/
Group consultations for Type 2 Diabetes: https://www.knowdiabetes.org.uk/professional/group-consultations/
Medication for Type 2 Diabetes: https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication
Air pollution and Type 2 Diabetes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931138/
Shift work and diabetes: https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-023-16091-y
Dr David Unwin: https://amp.theguardian.com/society/2023/apr/09/british-doctor-pioneers-low-carb-diet-as-cure-for-obesity-and-type-2-diabetes
Low carb diets: https://www.diabetes.co.uk/diet/low-carb-diabetes-diet.html
Gut microbes and Type 2 Diabetes: https://www.sciencedirect.com/science/article/pii/S0955286318303073
Evidence for CGM (continuous glucose monitoring): https://www.ajmc.com/view/continuous-glucose-monitoring-overview-features-and-evidence (eg Dexcom/ Libre)
Zoe app: https://zoe.com/ (one example of an app which combines analysis of gut microbes and CGM)
GAD antibodies and Diabetes development: https://www.healthline.com/health/diabetes/gad-antibodies
THE HEALTH FIX: https://www.amazon.co.uk/Health-Fix-Transform-Your-Weeks/dp/1914239296/ref=tmm_hrd_swatch_0?_encoding=UTF8&qid=1698178460&sr=1-1
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203. Invisible Habits that can sabotage our health - some reflections
15:14||Season 1, Ep. 203In this episode I look at things that can hamper our health journey by looking at our own life in an easy and compassionate way.Links:The Health Fix on Kindle offer January 2026: https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja-ebook/dp/B0B2VTFFVS/ref=tmm_kin_swatch_0Sleep and its importance: https://pmc.ncbi.nlm.nih.gov/articles/PMC6281147/Phone and screen usage: https://pmc.ncbi.nlm.nih.gov/articles/PMC11236742/Decluttering: https://drayanpanja.substack.com/p/decluttering-your-home-how-it-could-1fd\\Exercise: https://www.sciencefocus.com/wellbeing/exercise-snacksImpulsivity: https://www.healthline.com/health/mental-health/impulsive-behavior#Impulsive-behavior-meaningOverwhelm: https://www.bbc.co.uk/sounds/play/m002pf4w
202. 2026 - the year of discernment and choices
14:35||Season 1, Ep. 202It’s a new year and that can feel overwhelming.In this episode I look at what the year is likely to bring in terms of health and medical trends, our own personal goals and how to generate ideas for them if you are feeling a bit stuck.Links: The Health Fix: https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja-ebook/dp/B0B2VTFFVSMed tech in 2026: https://www.forbes.com/sites/bernardmarr/2025/10/27/the-8-biggest-healthcare-technology-trends-to-watch-in-2026/Misinformation - how to spot it: https://news.cancerresearchuk.org/2024/02/16/sorting-fact-from-fiction-a-guide-to-spotting-health-misinformation/
201. Christmas time reflection 2025
11:45||Season 1, Ep. 201Links:AI in medicine: https://www.england.nhs.uk/long-read/guidance-on-the-use-of-ai-enabled-ambient-scribing-products-in-health-and-care-settings/Various wearables: https://uk.wellnesspulse.com/lp/best-fitness-trackers/?campaignId=23304304009&adgroupId=&adId=&targetId=&device=c&gunique=CjwKCAiAmKnKBhBrEiwAaqAnZ4MBo1x_tOV7RB1FPjSEqiYWae8AyeixJJsGEVTlbapiaEWJL7D8cBoCYs8QAvD_BwE&gad_source=1&gad_campaignid=23300097782&gbraid=0AAAAAqKJRpkXwMKHsYb3EhuFeRzIdPUV2Health Check on BBC World Service: https://www.bbc.co.uk/sounds/play/w3ct6vk0Elinzanetant for menopause: https://www.gov.uk/government/news/mhra-approves-elinzanetant-to-treat-moderate-to-severe-vasomotor-symptoms-hot-flushes-caused-by-menopauseThe new weight loss drugs (GLP-1 agonists): https://my.clevelandclinic.org/health/treatments/13901-glp-1-agonistsExperimental Alzheimer’s Drug: https://www.sciencedaily.com/releases/2025/12/251222080119.htm
200. Episode 200: reflections, precision medicine and the one thing we should all be doing.
15:50||Season 1, Ep. 200This is my 200th episode and I reflect on where medicine is at in terms of precision medicine and what it means for us.Links:Please take this 10 minute survey to help keep this podcast going: http://bit.ly/savinglivesinslowmotion-surveyGenome sequencing: https://www.genomicsengland.co.uk/blog/what-happens-when-i-go-for-whole-genome-sequencingMepan Syndrome: https://umdf.org/mepan/Ketones in dementia: https://pmc.ncbi.nlm.nih.gov/articles/PMC8734638/London Bus study: https://cardiachealth.org.uk/the-london-busmen-study/Drumming - physical and mental therapy?: https://melodics.com/blog/mental-health-benefits-of-drumming
199. Traditional Medicine: ancient global healing knowledge in today’s world
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198. Anti-ageing - what really works
16:35||Season 1, Ep. 198Anti-ageing means different things to different people. In this episode I look at what it means and what works to slow down the ageing process.Reactive oxygen species: https://www.ahajournals.org/doi/10.1161/circresaha.117.311401Mitochondria and ageing: https://www.nature.com/articles/s41574-021-00626-7Inflammation (inflammaging): https://www.nature.com/articles/s41574-018-0059-4Epigenetic drift: https://pmc.ncbi.nlm.nih.gov/articles/PMC12487821/Protein misaggregation: https://www.buckinstitute.org/blog/unraveling-aging-how-protein-misfolding-relates-to-aging-and-disease/Dietary patterns: https://www.medicalnewstoday.com/articles/fasting-like-diet-may-help-reverse-biological-aging-2-5-yearsGut microbes: https://www.nature.com/articles/s41575-022-00605-xRapamycin - an experimental drug for anti-ageing: https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00258-1/fulltextSenolytics: https://pmc.ncbi.nlm.nih.gov/articles/PMC7405395/Stem cells: https://pmc.ncbi.nlm.nih.gov/articles/PMC10276889/NAD / NAD+: https://www.today.com/health/aging/nad-benefits-rcna180800
197. Self diagnosis - the perils and marvels of searching for health and illness
15:08||Season 1, Ep. 19780% of us go online to look up health related content. Many of us look up symptoms which is natural but how do we know we are doing it safely? Here I look at the pros and pitfalls of doing this and how to decide when to see a medical professional. Links: Peripheral neuropathy: https://www.nhs.uk/conditions/peripheral-neuropathy/Internet vs GP 2013 (me on BBC1): https://www.bbc.co.uk/programmes/p019px0xDigital triage: https://www.england.nhs.uk/long-read/digitally-enabled-triage/Trust in doctors: https://www.wsj.com/health/wellness/why-we-dont-trust-doctors-like-we-used-to-79784b56Depression questionnaire: https://patient.info/doctor/mental-health/phq-9National Back Pain pathway: https://www.southtees.nhs.uk/services/back-pain/national-low-back-and-radicular-pain-pathway/Ada Health - on of the leaders in symptom checking: https://ada.com/
196. Osteoarthritis - its scale, future treatments and prevention
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195. Superfoods: the lowdown
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