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B12 deficiency - the truth about it and the latest NICE guidance behind this all-important public health issue
B12 deficiency affects up to 20% of people over the age of 60. It is often left undiagnosed but can present
in many ways. In this episode I look at the nuance involved in making the diagnosis and treating it appropriately
so that people do not come to harm.
NICE guidance: https://www.nice.org.uk/guidance/ng239
B vitamins: https://www.healthline.com/health/food-nutrition/vitamin-b-complex#What-is-vitamin-B-complex?
Dr Casimir Funk: https://www.newscientist.com/article/2418743-casimir-funk-the-scientist-who-gave-us-the-word-vitamin/
Beri-beri (B1 deficiency): https://medlineplus.gov/ency/article/000339.htm
Pernicious anaemia: https://www.healthline.com/health/pernicious-anemia
B12 food sources: https://www.medicalnewstoday.com/articles/vitamin-b12-foods
Drugs that affect B12: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054240/
Thyroid eye disease: https://my.clevelandclinic.org/health/diseases/17558-thyroid-eye-disease
MMA testing: https://labtestsonline.org.uk/tests/methylmalonic-acid
Active B12: https://www.nice.org.uk/advice/mib40/chapter/introduction
A decent explanation of methylation and why not all types of B12 and folate are the same for all: https://drkellymccann.com/beginners-guide-to-methylation-and-b-vitamins/
Caution with B12/folate fortified foods if you have a methylation issue as they can be in the wrong form: https://zoe.com/learn/fortified-foods#
Sublingual B12 vs oral vs infection: https://link.springer.com/article/10.1007/s11845-023-03602-4#
THE HEALTH FIX - the best health book in the world?! https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326
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151. The 8 habits that might help you live 20 years longer
15:19||Season 1, Ep. 151In this episode I look at a huge study from the USA which looked at over 700,000 people to find which habits lead others to increased lifespan.I discuss the limitations of the study but also some universal habits we could all potentially benefit from.The study: https://www.sciencedirect.com/science/article/pii/S000291652366280X?via%3DihubStudy summary: https://pubmed.ncbi.nlm.nih.gov/38065710/Exercise benefits: https://www.healthline.com/nutrition/10-benefits-of-exerciseAll Trials (Ben Goldacre): https://www.alltrials.net/The latest on the opioid crisis: https://www.bbc.co.uk/news/world-us-canada-65764307. (The dramatisations of this story, Painkiller and Dopesick are both available to watch on Netflix)What is an observational study?: https://www.mrcctu.ucl.ac.uk/patients-public/about-clinical-trials/what-is-an-observational-study/O Sleep (by Handel): https://www.youtube.com/watch?v=kJr5Uvi7fM4 Plant-based diets: https://nutritionj.biomedcentral.com/articles/10.1186/s12937-023-00877-2A framework to help create or break habits:https://www.glamourmagazine.co.uk/article/the-health-fix-dr-ayan-panja-new-years-resolutions150. 2025 - the year of letting go
13:21||Season 1, Ep. 150This year instead of wanting to take on new habits and do more I want to let go of things that are holding me back. In true Health Fix style it’s all about Too Little vs Too Much and I am shedding the too much bits!Toxic behaviours by others, phones in the morning, all or nothing and forgiveness all feature.Links: Marie Kondo and KonMari: https://konmari.com/Boundary setting: https://psychcentral.com/relationships/what-are-personal-boundaries-how-do-i-get-someForgiveness vs moving on: https://www.psychologytoday.com/gb/blog/the-forgiving-life/201809/is-there-difference-between-forgiving-and-movingComparisons with others: https://www.psychologytoday.com/gb/articles/201711/the-comparison-trapChanging an all or nothing mindset: https://chadd.org/adhd-weekly/replace-an-all-or-nothing-mindset-with-balanced-thinking/Phone use in the morning: https://www.fielding.edu/how-morning-phone-habits-shape-productivity-and-well-being/#BUY THE HEALTH FIX PAPERBACK NOW: https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=&sr=148. Reflection - why it’s good for us
12:45||Season 1, Ep. 148There is consensus on how reflection is good for mental health as well as productivity but how can we easily make time for it on the modern world?In this episode at this reflective time of year I look at how we might be able to do it little and often.The power of self-reflection: https://hbr.org/2022/03/dont-underestimate-the-power-of-self-reflectionJournalling benefits: https://psychcentral.com/lib/the-health-benefits-of-journalingReflection and productivity: https://www.library.hbs.edu/working-knowledge/the-pause-that-brings-peace-and-productivity147. Anaemia 101
14:51||Season 1, Ep. 147In this episode I cover the different type so anaemia as I have found it can cause much confusion and there are so many different types, from mild iron deficiency to types that can be life threatening. Iron deficiency anaemia: https://www.nhs.uk/conditions/iron-deficiency-anaemia/Bone marrow: https://my.clevelandclinic.org/health/body/22818-bone-marrowHaem and non haem iron: https://www.mkuh.nhs.uk/patient-information-leaflet/good-sources-of-ironVitamin C and iron: https://www.canr.msu.edu/news/iron_and_vitamin_c_the_perfect_pairAplastic anaemia: https://www.gosh.nhs.uk/conditions-and-treatments/conditions-we-treat/aplastic-anaemia/Pernicious anaemia: https://my.clevelandclinic.org/health/diseases/22377-pernicious-anemiaAnaemia of chronic disease: https://my.clevelandclinic.org/health/diseases/14477-anemia-of-chronic-diseaseMCV on a blood count: https://medlineplus.gov/lab-tests/mcv-mean-corpuscular-volume/Leukaemia: https://www.cancerresearchuk.org/about-cancer/leukaemiaHaemolytic anaemia: https://www.hopkinsmedicine.org/health/conditions-and-diseases/hemolytic-anemiaSickle cell disease: https://www.nhs.uk/conditions/sickle-cell-disease/Thalassemia: https://my.clevelandclinic.org/health/diseases/14508-thalassemiasIron diet sheet: https://kingstonhospital.nhs.uk/information/iron-diet-sheet/Eating your greens: https://pubmed.ncbi.nlm.nih.gov/34034049/146. Liver health - fatty liver disease, jaundice, preventive measures and more
18:15||Season 1, Ep. 146In this episode I look at the liver and how to keep it healthy, arguably the most industrious visceral organ in our body with so many critical functions. Non-Alcoholic Fatty Liver Disease: https://www.hopkinsmedicine.org/health/conditions-and-diseases/nonalcoholic-fatty-liver-diseaseFructose: https://www.nih.gov/news-events/nih-research-matters/how-high-fructose-intake-may-trigger-fatty-liver-diseaseGlycogen: https://my.clevelandclinic.org/health/articles/23509-glycogenUltra processed food and liver disease: https://pubmed.ncbi.nlm.nih.gov/37871746/Alcohol and liver disease: https://www.hopkinsmedicine.org/health/conditions-and-diseases/alcoholinduced-liver-diseaseWIlson’s Disease: https://www.mayoclinic.org/diseases-conditions/wilsons-disease/symptoms-causes/syc-20353251Haemochromatosis: https://www.haemochromatosis.org.uk/Jaundice: https://www.nhs.uk/conditions/jaundice/Gall bladder removal - cholecsytecomy: https://my.clevelandclinic.org/health/procedures/21614-gallbladder-removalDiarrhoea after gall bladder removal: https://pmc.ncbi.nlm.nih.gov/articles/PMC10725554/Hepatitis 'alphabet': https://www.who.int/news-room/questions-and-answers/item/hepatitisGallbladder diet: https://www.healthline.com/health/gallbladder-dietMetabolic pathways in detoxification: https://onlinelibrary.wiley.com/doi/10.1155/2015/760689Coffee and other foods: https://www.medicalnewstoday.com/articles/323915145. Winter Health 101
13:30||Season 1, Ep. 145It’s a time of year that some people dread but there’s so much we can do get through this season and I look at that in this short but useful 101 episode.Polyphenols and hormesis: https://www.sciencedirect.com/science/article/abs/pii/S0958166924000107Vitamin C and zinc for colds: https://pubmed.ncbi.nlm.nih.gov/32342851/Asthma exacerbations and vitamin D: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(17)30306-5/fulltext#Non IgE cows milk protein allergy: https://www.allergyuk.org/about-allergy/allergy-in-childhood/cows-milk-allergy/ (can cause cough if drinking milk) SAD: https://www.mayoclinic.org/diseases-conditions/seasonal-affective-disorder/symptoms-causes/syc-20364651Morning light (Russell Foster): https://www.neuroscience.ox.ac.uk/news/professor-russell-foster-receives-daylight-award-2020Food cravings in winter: https://www.independent.co.uk/health-and-wellbeing/winter-diet-cold-weather-food-b2621804.htmlFlu (Influenza): https://my.clevelandclinic.org/health/diseases/4335-influenza-fluExercise in winter health: https://www.heart.org/en/healthy-living/fitness/getting-active/how-to-stay-active-in-cold-weather144. Back Pain
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