Rings a Bell

Episode 4 provides- A refresher on how red blood cells are formed, their lifecycle and inputs- An overview of the major types of anemia classified by pathophysiology and histology (how the red blood cells look under a slide)- Some simple physical symptoms that pharmacists can look for in practice and what they might indicate- A refresher on the major guidelines for iron deficiency anemia including a recent update- Some excellent case studies detailing the complexity of dealing with patients who have chronic inflammation AND anemia- New this episode: some semi-useful notes in pdf form from me to you. Merry Christmas ya bunch of hooligans!Links:Find all the links to all the things here: https://ringsabellpod.kit.com/allthethings Find Jenny at: https://www.linkedin.com/in/jenny-hsieh-435828177/References:See all the links above.

Keywords:insulin sensitivity, metformin, blood sugar management, dietary approaches, microbiome, GLP-1 agonists, functional medicine, probiotics, metabolic health, clinical signsSummary:Episode 3 part 1 covers general metabolic health as it relates to pharmaceuticals, the microbiome and nutrition. My guest is Dr. Alex Nataros, a family doctor practicing in Port Hardy, BC.Subscribe to the Rings a Bell email list here: https://ringsabellpod.kit.com/subscribeTo become a guest on the show email ringsabellpodcast@gmail.comReferences: Weight Gain Drugshttps://pmc.ncbi.nlm.nih.gov/articles/PMC6109660/Weight loss drugshttps://mobile.fpnotebook.com/Endo/Pharm/MdctnsAsctdWthUntntnlWghtLs.htmInsulin Sensitivity DrugsGiglio RV, Papanas N, Rizvi AA, Ciaccio M, Patti AM, Ilias I, Pantea Stoian A, Sahebkar A, Janez A, Rizzo M. An Update on the Current and Emerging Use of Thiazolidinediones for Type 2 Diabetes. Medicina. 2022; 58(10):1475. https://doi.org/10.3390/medicina58101475Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, Araújo AC, de Souza Gonzaga HF, de Bortoli Teixeira D, de Oliveira Silva Ullmann T, et al. GLP-1a: Going beyond Traditional Use. International Journal of Molecular Sciences. 2022; 23(2):739. https://doi.org/10.3390/ijms23020739https://doi.org/10.1016/j.redox.2020.101517 (Mechanisms of Action of metformin in type 2 diabetes: effects on mitochondria and leukocyte endothelium interactions.Microbiome and obesity: https://doi.org/10.1016/j.biopha.2022.112678Sohail MU, Althani A, Anwar H, Rizzi R, Marei HE. Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus. J Diabetes Res. 2017;2017:9631435. doi:10.1155/2017/9631435HMF Metabolic:Michael DR, Jack AA, Masetti G, et al. A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Sci Rep. 2020;10(1):4183. Published 2020 Mar 6. doi:10.1038/s41598-020-60991-7UltraFlora Control:Stenman LK, Lehtinen MJ, Meland N, et al. Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial. EBioMedicine. 2016;13:190-200. doi:10.1016/j.ebiom.2016.10.036Super intense study on personalized nutrition published in cell that I talked too long about :) Zeevi D, Korem T, Zmora N, et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 2015;163(5):1079-1094. doi:10.1016/j.cell.2015.11.001        

On this episode of the Rings A Bell Pharmacy Podcast I welcome on Cheen-Young Liu. A bright star from U of T's PharmD program, she schools me on contraception!References from Cheen-Young:·     CPS (Compendium of Pharmaceuticals and Specialties) - Contraception·     Up To Date (I can't remember which specific pages I used, I viewed a lot but didn't necessarily use all of them)·     Class notes from Dr. Thomas Brown ·     HC Monograph - TARO-MEDROXYPROGESTERONE INJECTION (https://pdf.hres.ca/dpd_pm/00080310.PDF)·     HC Monograph - Evra patch (https://pdf.hres.ca/dpd_pm/00077976.PDF)HC Monograph - NuvaRing (https://pdf.hres.ca/dpd_pm/00077755.PDF)·     BC College of Pharmacists Conscientious Objection (https://www.bcpharmacists.org/faq/how-does-conscientious-objection-work-pharmacy-practice) References from Kim:·     Bone mineral density and Depo-Provera mechanism: Article Titled Estrogen Supplementation with Depot Medroxyprogesterone found at: https://www.aafp.org/pubs/afp/issues/2005/1015/p1602.html·     Mirena as emergency contraception: This changed my practice article found at https://thischangedmypractice.com/iud-for-emergency-contraception/