Pestpodden

  • Scepticaemia - helping find meaning in science

    34:26
    We meet Paul Garner (prof. emerit. and one of the founding fathers of Cochrane) and Rebecca Kuehn (Cochrane infectious diseases) for a talk about evidence-based medicine, critical appraisal and all things related to how we interpret and find the "truth" within research.Resources:1. Ioannidis JP. Why most published research findings are false. PLoS Med. 2005;2(8):e124.2. Garner P, Taylor-Robinson D, Sachdev HS. DEVTA: results from the biggest clinical trial ever. Lancet. 2013;381(9876):1439-41.3. Gigerenzer G. Making sense of health statistics. Bull World Health Organ. 2009;87(8):567.4.https://www.badscience.net/2010/07/yeah-well-you-can-prove-anything-with-science/5. de Souza DK, Thomas R, Bradley J, Leyrat C, Boakye DA, Okebe J. Ivermectin treatment in humans for reducing malaria transmission. Cochrane Database Syst Rev. 2021;6(6):CD013117.6. Foy BD, Alout H, Seaman JA, Rao S, Magalhaes T, Wade M, et al. Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial. Lancet. 2019;393(10180):1517-26.7. Popp M, Reis S, Schiesser S, Hausinger RI, Stegemann M, Metzendorf MI, et al. Ivermectin for preventing and treating COVID-19. Cochrane Database Syst Rev. 2022;6(6):CD015017.8. Hadinegoro SR, Arredondo-Garcia JL, Capeding MR, Deseda C, Chotpitayasunondh T, Dietze R, et al. Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease. N Engl J Med. 2015;373(13):1195-206.9. Dans AL, Dans LF, Lansang MAD, Silvestre MAA, Guyatt GH. Controversy and debate on dengue vaccine series-paper 1: review of a licensed dengue vaccine: inappropriate subgroup analyses and selective reporting may cause harm in mass vaccination programs. J Clin Epidemiol. 2018;95:137-9.10. Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64(4):383-94.11. https://bestpractice.bmj.com/info/toolkit/learn-ebm/what-is-grade/12.Guyatt G, Vist G, Falck-Ytter Y, Kunz R, Magrini N, Schunemann H. An emerging consensus on grading recommendations? ACP J Club. 2006;144(1):A8-9.
  • 14. Filarial nematodes (english version)

    52:30
    This is the "all-english"-version of the filaria-episode: Pestpodden presents a tropical topic that many of us struggle with understanding: filarial nematodes. Professor Mark Taylor - one of the worlds leading experts on filarial nematodes - guides us through this difficult topic - and presents some breaking research-news at the end of the episode.
  • 14. Filarioser

    57:14
    Tropisk episode! Pestpodden snakker om filarioser med professor Mark Taylor - en av verdens ledende eksperter innen feltet. Dette er en faglig tung episode, men er du tropemedisinsk interessert og har lyst til å lære mer - så er dette episoden for deg! I tillegg presenteres noen "breaking news" fra forskningsverdenen mot slutten av episoden som du kan glede deg til.
  • 13. Ukraina og multiresistens

    50:26
    Det multiresistente fremtidsscenarioet ble plutselig virkelighet. Kristian Tonby forteller om sitt møte med evakuerte krigsskadde pasienter fra Ukraina, og om hvordan vi kan håndtere multiresistente mikrober. Litteratur:Metodebok i infeksjonsmedisin, OUS: Infeksjoner med multiresistente bakterier (metodebok.no) Medevac: https://www.oslo-universitetssykehus.no/avdelinger/direktorens-stab/stab-medisin-helsefag-og-beredskap/medevac/
  • 12. (U)hyggelig vertskap

    38:51
    Ingrid og Jørgen snakker (mest) løst og (litt) fast om parasitter og vertskap. Fra zombiesoppen i serien "The last of us", drar vi på vandring videre gjennom noen av verdens (ekte) parasitter. Bli med på parasittekspedisjon! Referanser:1. Backman I. “The Last of Us” Apocalypse Is Not Realistic, But Rising Threat of Fungal Pathogens Is. Yale school of medicine - webpage. 2023.2. Del Brutto OH, Garcia HH. Taenia solium Cysticercosis--The lessons of history. J Neurol Sci. 2015;359(1-2):392-5.3. Hughes DP, Andersen SB, Hywel-Jones NL, Himaman W, Billen J, Boomsma JJ. Behavioral mechanisms and morphological symptoms of zombie ants dying from fungal infection. BMC Ecol. 2011;11:13.4. Kintzen W. The Caduceus Motif and The Guinea Worm. JAMA. 1968;203(3):234-.5. Pontoppidan MB, Himaman W, Hywel-Jones NL, Boomsma JJ, Hughes DP. Graveyards on the move: the spatio-temporal distribution of dead ophiocordyceps-infected ants. PLoS One. 2009;4(3):e4835.6. Rosania K. Tricking rats into liking cats. Lab Anim (NY). 2011;40(10):288.7. Saevik BK, Krontveit RI, Eggen KP, Malmberg N, Thoresen SI, Prestrud KW. Toxoplasma gondii seroprevalence in pet cats in Norway and risk factors for seropositivity. J Feline Med Surg. 2015;17(12):1049-56.8. Webster JP. Rats, cats, people and parasites: the impact of latent toxoplasmosis on behaviour. Microbes Infect. 2001;3(12):1037-45.9. Wilcox RA, Whitham EM. The symbol of modern medicine: why one snake is more than two. Ann Intern Med. 2003;138(8):673-710 Save the guinea-worm-foundation: http://www.deadlysins.com/guinea-worm11 Ophiocordyceps unilateralis - Wikipedia
  • 11. Antibiotikaresistens del 2

    25:47
    Norwegian:Vi intervjuer en av verdens fremste eksperter og forskere på antimikrobiell resistens: Adam Roberts fra Liverpool School of Tropical Medicine! Episoden finnes også i engelsk versjon.References/supplementary reading:1. Allel K, Day L, Hamilton A, Lin L, Furuya-Kanamori L, Moore CE, et al. Global antimicrobial-resistance drivers: an ecological country-level study at the human-animal interface. Lancet Planet Health. 2023;7(4):e291-e303.2. Roberts AP. Swab and Send: a citizen science, antibiotic discovery project. Future Sci OA. 2020;6(6):FSO477.3. AMR Review. https://amr-review.org/
  • Antimicrobial resistance part 2 (english version)

    25:27
    In this first-ever english episode of Pestpodden, we are interviewing one of the worlds leading experts and researchers within the field of antimicrobial resistance; Adam Roberts from Liverpool School of Tropical Medicine. There is hope! References/supplementary reading:1. Allel K, Day L, Hamilton A, Lin L, Furuya-Kanamori L, Moore CE, et al. Global antimicrobial-resistance drivers: an ecological country-level study at the human-animal interface. Lancet Planet Health. 2023;7(4):e291-e303.2. Roberts AP. Swab and Send: a citizen science, antibiotic discovery project. Future Sci OA. 2020;6(6):FSO477.3. AMR Review. https://amr-review.org/
  • 10. Antibiotikaresistens del 1

    14:01
    Synes du også resistens er vanskelig? Fatt mot og bli med oss i Pestpodden på en reise gjennom resistensen! I anledning Antibiotikauken 2023 har vi nemlig to spesialepisoder. I del èn får du en enkel intro til antimikrobiell resistens - mens i del to intervjuer vi en av verdens fremste eksperter og forskere på feltet; Adam Roberts. Gled deg!Referanser:1. Barlow M, Hall BG. Phylogenetic analysis shows that the OXA beta-lactamase genes have been on plasmids for millions of years. J Mol Evol. 2002;55(3):314-21.2. D'Costa VM, King CE, Kalan L, Morar M, Sung WW, Schwarz C, et al. Antibiotic resistance is ancient. Nature. 2011;477(7365):457-61.3. Holmes AH, Moore LS, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, et al. Understanding the mechanisms and drivers of antimicrobial resistance. Lancet. 2016;387(10014):176-87.4. Woerther PL, Andremont A, Kantele A. Travel-acquired ESBL-producing Enterobacteriaceae: impact of colonization at individual and community level. J Travel Med. 2017;24(suppl_1):S29-s34.5. NORM/NORM-VET 2022. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway. Tromsø / Oslo 2023. ISSN:1502-2307 (print) / 1890-9965 (electronic). . 2022.7. https://atlas.ecdc.europa.eu/public/index.aspx?Dataset=27&HealthTopic=48. Antimicrobial Resistance C. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629-55.
  • Fellesepisode - Den grufulle vegen til i dag

    01:14:46
    Endelig har Helse Bergen både fått nok podkaster, og klart å få samla gjengen til ein fellesepisode! I denne tverrfaglige bonusepisoden, utgitt den siste dagen i oktober like før sukkeret tar fullstendig overhand, oppsummerer karkirugane, ortopedane, infeksjonsmedisinarane og anestesi- og soveekspertane korleis vi har kome til det vi kjenner som moderne sjukehus og behandling. Som du gjerne gjetta - det har ikkje vore ei særleg hyggjeleg reise, men skal du lage god omelett så må du knuse nokre... egg.
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