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AI-designed antivenoms could help treat lethal snakebites
Researchers have shown that machine learning can quickly design antivenoms that are effective against lethal snake-toxins, which they hope will help tackle a serious public health issue. Thousands of people die as a result of snakebites each year, but treatment options are limited, expensive and often difficult to access in the resource-poor settings where most bites occur. The computer-aided approach allowed researchers to design two proteins that provided near total protection against individual snake toxins in mouse experiments. While limited in scope, the team behind the work believe these results demonstrate the promise of the approach in designing effective and cheaper treatments for use in humans.
Research Article: Vázquez Torres et al.
How male wasp spiders use hairs on their legs to sniff out mates, and how noradrenaline drives waves of cleansing fluid through the brain.
Research Highlight: Male spiders smell with their legs
Research Highlight: How the brain cleans itself during deep sleep
News broke last week that in 2024, Earth’s average temperature climbed to more than 1.5 °C above pre-industrial levels for the first time. Although this is only a single year so far, we discuss what breaking this significant threshold means for the 2015 Paris climate agreement and what climate scientists understand about the speed that Earth is heating up.
Nature: Earth breaches 1.5 °C climate limit for the first time: what does it mean?
NASA delays deciding its strategy for collecting and returning Mars rocks to Earth, and why papers on a handful of bacterial species dominate the scientific literature.
Nature: NASA still has no plan for how to bring precious Mars rocks to Earth
Nature: These are the 20 most-studied bacteria — the majority have been ignored
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Behind the scenes with Artemis II’s scientists during the historic Moon fly-by
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Briefing Chat: The tongue trick that helps sunbirds suck
13:52|In this episode:00:41 Exosome therapies could deliver drugs to hard to reach placesNature: Eye drops made from pig semen deliver cancer treatment to mice5:08 The impact of parenthood on women’s academic careersNature: Motherhood derails women’s academic careers — these data reveal how and why10:34 The unusual suction that lets Sunbirds drinkScience: These birds suck—literallySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Artemis II is go: humans head to the Moon after half-century absence
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24:48|In this episode:00:46 Collecting contrails at 30,000 feetResearch Article: Voigt et al.11:23 Research HighlightsNature: Sunken Soviet nuclear submarine’s radioactive releaseNature: History of ‘forever’ chemicals is written in Antarctic snow13:34 Fakery in scienceApril Fakes DaySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
Briefing Chat: ‘Zombie cells’ resurrected with new genes
11:01|Nature staff discuss some of the week's top science news.00:18 ‘Zombie cells’ revived with genome transplantNature: ‘Zombie cells’ return from the dead — after a genome transplant05:27 A limit to cloning, in miceNature: Can a mouse be cloned indefinitely? Decades-long experiment has answersSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Why insects aren't huge: a new challenge to a decades-old idea
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Briefing Chat: Are scientists funny? The evidence is in — and it's no joke
09:52|In this episode:00:22 Exploring how gut microorganisms contribute to ageingNature: Memory loss is fuelled by gut microbes in ageing mice04:30 How good jokes are in short supply during academic conferencesNature: Knock knock, no one’s there. Study finds scientists’ jokes mostly fall flatSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Botanical mystery solved: how plants make a crucial malaria drug
15:55|In this episode:00:46 Piecing together a biochemical puzzleResearch Article : Lombe et al.12:26 Research HighlightsNature: Electric-vehicle batteries toughen up to beat the heatNature: Live parrots were carried across the Andes before the Incas’ rise
Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
10:34|00:26 Why researchers keep using Doom in their researchNature: How the classic computer game Doom became a tool for scienceSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.