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AI-designed antivenoms could help treat lethal snakebites
Researchers have shown that machine learning can quickly design antivenoms that are effective against lethal snake-toxins, which they hope will help tackle a serious public health issue. Thousands of people die as a result of snakebites each year, but treatment options are limited, expensive and often difficult to access in the resource-poor settings where most bites occur. The computer-aided approach allowed researchers to design two proteins that provided near total protection against individual snake toxins in mouse experiments. While limited in scope, the team behind the work believe these results demonstrate the promise of the approach in designing effective and cheaper treatments for use in humans.
Research Article: Vázquez Torres et al.
How male wasp spiders use hairs on their legs to sniff out mates, and how noradrenaline drives waves of cleansing fluid through the brain.
Research Highlight: Male spiders smell with their legs
Research Highlight: How the brain cleans itself during deep sleep
News broke last week that in 2024, Earth’s average temperature climbed to more than 1.5 °C above pre-industrial levels for the first time. Although this is only a single year so far, we discuss what breaking this significant threshold means for the 2015 Paris climate agreement and what climate scientists understand about the speed that Earth is heating up.
Nature: Earth breaches 1.5 °C climate limit for the first time: what does it mean?
NASA delays deciding its strategy for collecting and returning Mars rocks to Earth, and why papers on a handful of bacterial species dominate the scientific literature.
Nature: NASA still has no plan for how to bring precious Mars rocks to Earth
Nature: These are the 20 most-studied bacteria — the majority have been ignored
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Briefing Chat: How 1,000 pairs of buried underpants helped measure soil health
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Audio long read: Could mending damaged DNA prolong life?
18:16|Scientists are amassing evidence that unrepaired or poorly repaired DNA damage underlies many of the hallmarks of ageing. This has led to research into whether boosting DNA repair can keep people healthy for longer.This is an audio version of our Feature: Could mending damaged DNA prolong life?
Briefing Chat: How Dolly Parton left her mark on science
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Highest-ever ocean temperatures recorded as El Niño intensifies
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Briefing Chat: New narcolepsy drug could unlock host of novel brain therapies
12:25|Nature staff discuss how an FDA-approved drug for narcolepsy could have promise beyond the condition, and the longest-lived human brain organoids yet.00:28 The promise of a new narcolepsy drugNature: First-of-its-kind narcolepsy drug opens door to new therapies for the brain05:53 Human brain organoids kept alive for over five yearsNature: Human organoids that mimic brain development grown for years in labSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
A black hole's spin could finally be measured by a high-speed star
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Briefing Chat: Anthropic rolls out new AI watermark — will it make a difference?
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The probiotic bacteria engineered to treat diabetes
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Briefing Chat: Is DNA repair the secret to a long life? Whales and mole-rats offer tantalizing hints
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