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Does mood and coping affect my pain?
Dr. Keefe is a professor in the department of psychiatry and behavioral sciences at Duke University Medical Center and a member of the Cancer Prevention, Detection, and Control Program of the Duke Comprehensive Cancer Center. He is director of the Duke Pain Prevention and Treatment Research Program, an active clinical research program concerned with the behavioral assessment and treatment of patients having acute and persistent pain. Dr. Keefe has developed and refined a number of treatment protocols for persistent pain conditions (e.g. cancer, arthritis) including spouse and partner-assisted pain coping skills training interventions. He has conducted a number of randomized clinical trials testing the efficacy of these and other behavioral interventions (e.g. aerobic exercise protocols, yoga based interventions, mindfulness-based interventions, forgiveness-based interventions, loving kindness meditation, and emotional disclosure). Dr. Keefe has published over 400 papers, as well as 60 book chapters. He currently serves as the editor-in-chief of the journal PAIN.
On the show we discuss: persistent pain and how to manage pain with coping skills, understanding pain and how it is influenced, practical tips for managing pain
Resources
- painTRAINER website - an interactive online program based on scientific research that teaches you effective strategies to manage your pain
- Books by Kate Lorig, Michael Nicholas
More episodes
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12. Walking for joint health with Dr Sarah Kobayashi
22:22||Season 6, Ep. 12In this week's episode of Joint Action, Professor David Hunter is joined by Dr Sarah Kobayashi, a lecturer in anatomy and osteoarthritis researcher, to talk about the power of walking - especially for people with osteoarthritis.Sarah shares her insights into the many health benefits of walking, why it’s so important for joint health, and how to overcome common barriers to getting started. She also introduces the CASCADE-OA study (Community bAsed phySical aCtivity AnD sElf-management for OsteoArthritis), a 12-month clinical trial exploring the effectiveness of a self-directed walking program, Walk With Ease Australia, in improving physical activity levels and managing symptoms for those with hip or knee osteoarthritis.Whether you're new to walking or looking to establish a sustainable routine, this episode offers practical advice and motivation to help you take that first step.RESOURCES Learn more about the CASCADE-OA study and check your eligibility:CASCADE-OA Study Overview: www.osteoarthritisresearch.com.au/cascadeoa-study-overviewAsk your local arthritis organisation about Walk With Ease or the CASCADE-OA study: Arthritis Australia – www.arthritisaustralia.com.au/state-offices/Additional resources:Versus Arthritis Walking Guide (UK): www.versusarthritis.org/about-arthritis/exercising-with-arthritis/exercises/walkingHeart Foundation Walking Groups (Australia) – walking.heartfoundation.org.auParkrun Australia: www.parkrun.com.auCONNECT WITH US Twitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast11. Rethinking running and knee health with Dr Jean-Francois Esculier
26:43||Season 6, Ep. 11Running often gets a bad rap when it comes to knee osteoarthritis - but is the fear justified? In this week's episode of Joint Action, Professor David Hunter speaks with physiotherapist and researcher Dr Jean-François Esculier to unpack common myths about running and joint health. They explore the latest evidence, share tips for safe running with OA, and discuss how to build joint resilience over time.Tune in to learn why running might not just be safe - it could even be helpful.RESOURCESEducation resource on running and joint health, in 7 languages: http://hdl.handle.net/2429/82767 CONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast10. High heels, high risk? Investigating the impact of footwear on knees with Dr Kathryn Mills
33:15||Season 6, Ep. 10High heels have long been associated with fashion - but what impact do they have on your joints? This week, Professor David Hunter is joined by physiotherapist and footwear researcher Dr. Kathryn Mills to unpack the biomechanics of high heels and their effect on knee health.From changes in posture and joint compression to the importance of shoe comfort and replacement, this episode blends science with practical advice for anyone managing knee pain or osteoarthritis. Plus, learn what to look for in a good shoe and when to seek professional help from a podiatrist or physiotherapist.RESOURCESHuman Movement Montreal Instagram Page: https://www.instagram.com/humanmovementmontreal/Australian Podiatry Association: https://www.podiatry.org.au/foot-health-resources/footwear-adviceAustralian Podiatry Association Fact Sheets: https://www.podiatry.org.au/foot-health-resources/footwear-health-check/footwear-health-checkAustralian Podiatry Association Fact Sheets: https://www.podiatry.org.au/foot-health-resources/incorrectly-fitted-shoes/incorrectly-fitted-shoes CONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast9. New Joints, New Moves: How Joint Replacements Impact Physical Activity Levels with Dr Tim Lindsay
39:40||Season 6, Ep. 9Can joint replacements reduce pain, help you move more - and live longer? In this week's podcast episode, we explore the untold benefits of hip and knee replacements beyond pain relief. Dr Tim Lindsay, clinician and researcher at Imperial College London, joins us to share insights from large-scale studies that show how joint replacement can restore physical activity levels and potentially reduce premature mortality. We also discuss why recovery takes time, how expectations should be managed, and what patients can realistically achieve after surgery. If you're considering joint replacement or supporting someone who is, this conversation offers evidence-based clarity and hope.RESOURCESARTICLESDevice-Measured Physical Activity in 3506 Individuals with Knee or Hip Arthroplasty: https://pubmed.ncbi.nlm.nih.gov/38109175Wearable device measured physical activity and future health risk: https://www.nature.com/articles/s41591-020-1012-3 CONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast8. The risk of bias in trial design and what this means for clinical practice with Dr Bruno da Costa
37:48||Season 6, Ep. 8In this episode of Joint Action, Professor David Hunter is joined by Dr. Bruno da Costa, Associate Professor of Clinical Epidemiology at the University of Toronto and Senior Scientist at the University of Oxford, to unpack the evidence behind injections for osteoarthritis.Dr. da Costa shares insights from his recent systematic review and network meta-analysis of clinical trials, revealing just how limited - and at times unreliable - the evidence is for many joint injection therapies.This episode explores:Which injections (if any) offer real benefit - and for how longThe surprising extent of bias in osteoarthritis trialsWhy some results may not be as credible as they seemThe role of placebo effects and commercial influenceWhat this means for people living with osteoarthritisIf you’ve ever considered injection therapy, this episode will help you sort fact from fiction.RESOURCESS04E10 - Care for an oil change? The role of viscosupplementation for osteoarthritis wit Dr Bruno da Costa: https://www.jointaction.info/podcast/episode/6cda642b/care-for-an-oil-change-the-role-of-viscosupplementation-for-osteoarthritis-with-dr-bruno-da-costaInfographic - How effective are intra-articular interventions for osteoarthritis?: https://www.osteoarthritisresearch.com.au/s/0225-Clinical-Editors-Choice.pngArticle - Effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis based on large randomized trials: A systematic review and network meta-analysis: https://www.oarsijournal.com/article/S1063-4584(24)01389-X/fulltextCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast7. Driving change in osteoarthritis - strategies, barriers and consumer power with Louise Hardy
26:37||Season 6, Ep. 7For too long, people living with osteoarthritis have felt powerless - like there’s nothing they can do to influence change. But that couldn’t be further from the truth.In this powerful episode, Prof. David Hunter is joined by Louise Hardy, Director of Policy and Advocacy at Arthritis Australia, to explore how individuals can use their voice to drive meaningful change - especially in the lead-up to the Australian federal election.Louise shares practical ways you can support better care, fairer funding, and more accessible services for the 7 million Australians living with arthritis. They discuss the importance of community-led advocacy, out-of-pocket costs, gaps in clinical care, and how you can be part of the solution, today.Whether you live in Australia or abroad, this episode offers a roadmap for how your voice can make a difference - starting now. RESOURCESTake action by emailing your local MP via the Arthritis Australia microsite: https://arthritisaus.good.do/election25/Act-Now-25/Join the Arthritis Australia Champions program: https://arthritisaustralia.com.au/get-involved/arthritis-champions/Learn more about Arthritis Australia initiatives: https://arthritisaustralia.com.au/ CONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast6. Can MRI predict the development of osteoarthritis with Dr Ali Guermazi and Dr Alison Chang
38:56||Season 6, Ep. 6MRIs are increasingly used to detect early signs of osteoarthritis - but are they truly beneficial for most people? On this week's episode, we examine the role of MRI scans in diagnosing knee osteoarthritis, particularly in its early stages. Joined by leading experts Dr. Alison Chang, a professor of Physical Therapy at Northwestern University, and Dr. Ali Guermazi, a Radiology professor at Boston University, we explore the genuine value of MRIs. Our discussion highlights when these imaging tests can be helpful and when they might lead to unnecessary interventions. We also discuss why many MRI-detected changes don't actually progress into osteoarthritis and share practical advice for effectively managing knee health. Tune in for an evidence-based conversation to understand when MRIs truly add value - and when they may not. RESOURCESLearn more about the frequency of MRI-detected structural abnormalities in healthy, pain-free individuals: https://x.com/OACJournal/status/1843050098579943647View the diagram illustrating Alison Chang’s 'inverted-U curve' concept of how activity levels relate to body capacity: Capacity vs. Load graphs_Dr Alison Chang.pdfCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast5. Can a blood test predict the risk of osteoarthritis? A discussion with Dr Virginia Kraus
26:51||Season 6, Ep. 5What if you could know your risk of developing osteoarthritis years before symptoms appear? In this episode, we explore whether a blood test could provide those answers.Joining us on this week's episode is Dr. Virginia Kraus, a leading rheumatologist and researcher, to discuss her study that identified osteoarthritis risk up to 10 years in advance with 77% accuracy. We unpack what this means for early detection, the role of inflammation in disease progression, and how this research could shape future treatment and prevention strategies.Tune in to find out what the future of osteoarthritis detection could look like. RESOURCESThe MOST Study: www.bumc.bu.edu/rheumatology/research/clinical-trials/the-multicenter-osteoarthritis-study-most/CANTOS Trial: www.nejm.org/doi/full/10.1056/NEJMoa1707914 CONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast4. Hormones, menopause, and joint pain with Dr Ginni Mansberg
39:32||Season 6, Ep. 4Menopause is often referred to as "the change" and remains a complex and sensitive topic for many. Despite being historically under-discussed, it's crucial to address because of its profound impact on musculoskeletal health. Women are two to three times more likely than men to develop osteoarthritis, particularly around menopause. Changes in hormones, such as declining estrogen, can affect cartilage, bone density, inflammation, muscle health, and body weight - factors closely linked to joint pain and osteoarthritis symptoms. In this episode of the Joint Action Podcast, Dr. Ginny Mansberg, a GP and women's health expert, joins Prof. David Hunter to explore the intricate relationship between menopause and osteoarthritis. They discuss the physical and emotional challenges women face, including sleep disruption, weight gain, joint pain, and mental health issues like anxiety and depression. Dr. Mansberg shares valuable insights into how hormone replacement therapy (HRT) and lifestyle strategies, including exercise, can help manage symptoms and improve long-term health outcomes.Whether you're navigating menopause or supporting someone who is, this episode offers a compassionate, evidence-informed perspective on understanding and managing the journey.RESOURCESDr. Ginny Mansberg’s website: DrGini.com.auDr. Ginny Mansberg's book - The M Word: How to Thrive in Menopause: https://drginni.com.au/products/the-m-word-how-to-thrive-in-menopauseCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast