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Inside Precision Medicine Podcasts
Precision Psychiatry
Ep. 2
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This IPM podcast unpacks some of the important work being done by Emma Johnson PhD Assistant Professor | Department of Psychiatry Washington University School of Medicine - we discuss her mission to elucidate the genetic architecture of psychiatric disorders, particularly focusing on substance use and addictions. We hear about her ongoing research in understanding commonly used drugs such as alcohol and cannabis and the relationships between substance use disorders and other psychiatric disorders and mental health conditions, including schizophrenia, suicidal thoughts and behaviors, and chronic pain.
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3. Implementing Tumor Classification in the Lab – Practical Insights and Overcoming Barriers, community engagement
30:37||Season 2, Ep. 3Providing a roadmap for laboratories to adopt DNA methylation-based tumor classification, addressing workflow design, operational challenges, and community engagement. Discuss financial barriers and obstacles
2. Deep Dive - Advanced Sarcoma and other tumor Applications with Methylation Profiling
35:00||Season 2, Ep. 2Exploring the growing role of DNA methylation in classifying and predicting prognosis for sarcomas, while highlighting integration with array, NGS, and CNV analysis for complex profiling. And other tumors and applications
1. Expanding Applications and Updates in CNS Tumor Classification Guidelines – from research and boutique to broad clinical application
42:16||Season 2, Ep. 1How DNA methylation changed clinical management of CNS tumors and is being integrated into clinical guidelines, including cIMPACT-NOW updates and the impact of technological advances.
3. Tumor Molecular Classifiers Offer Patients New Hope
35:15||Ep. 3This IPM podcast highlights the impressive work of Lucas Santana dos Santos, director of bioinformatics and an assistant professor at Northwestern University’s Feinberg School of Medicine. Professor dos Santos discusses the origins and recent developments of molecular tumor classification techniques and how analyzing epigenetic signatures is enabling clinicians to diagnose and treat cancer patients more effectively. This illuminating conversation examines how classifiers are developed and touches on the role of various technologies including the workhorse methylation microarray, in addition to the challenges of creating a universal tumor classifier.
1. Pharmacogenetic Testing
40:38||Ep. 1In this new Inside Precision Medicine Podcast episode, sponsored by Illumina, we speak with Dr. Julio Monterrey, a Stanford-trained, board-certified psychiatrist and neuroscientist who specializes in diagnosing and treating complex cases. Dr. Monterrey is a keen observer of medical technology who has adopted pharmacogenetic (PGx) testing as a regular part of patient history taking. Through his experience, Dr. Monterrey has seen substantial benefits from PGx testing for his patients and his practice. He is now an advocate for wider adoption of PGx screening to guide and improve patient care. We spoke with Dr. Monterrey to hear what he has learned working with PGx testing in his psychiatry practice.