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Sperm Donor's Cancer Mutation Affects 197 Children

A sperm donor with a hidden cancer-causing mutation has fathered at least one hundred ninety-seven children across Europe, sparking concerns about the need for stricter limits on sperm donations globally. The donor, carrying Li-Fraumeni syndrome, had up to twenty percent of his sperm affected, leading to cancer diagnoses in ten of the sixty-seven children identified. The European Sperm Bank, which sold the sperm, admitted to exceeding local limits in some countries. This case underscores the importance of comprehensive screening and transparent communication in donor conception.

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