Share

cover art for Perils of being human – A conversation about kinetochore humanization with Dr. Guðjón Ólafsson

Genetics in Your World

Perils of being human – A conversation about kinetochore humanization with Dr. Guðjón Ólafsson

Season 1, Ep. 10
•

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Sarah Gilmour has a conversation with Dr. Guðjón Ólafsson of NYU Langone Health and University of Iceland about his attempts to “humanize” the yeast kinetochore and how the difficulties of doing so teach us about the evolution of essential kinetochore proteins. Read Dr. Ólafsson’s paper titled, “Humanization reveals pervasive incompatibility of yeast and human kinetochore components,” published in the January 2024 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkad260. 

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

More episodes

View all episodes

  • 13. The Fourth Chromosome Resource Project – A conversation with Dr. Stuart Newfeld

    40:11||Season 1, Ep. 13
    In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee chair Hassan Bukhari has a conversation with Dr. Stuart Newfeld of Arizona State University about the Fourth Chromosome Resource Project. Read Dr. Newfeld’s paper titled, “Fourth Chromosome Resource Project: a comprehensive resource for genetic analysis in Drosophila that includes humanized stocks,” published in the February 2024 issue of GENETICS: https://doi.org/10.1093/genetics/iyad201.  Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

  • 12. Building from the ground up: Pathogen 'omics in the age of advanced molecular methods — A conversation with Dr. Scott Dawson

    57:15||Season 1, Ep. 12
    In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Sarah Renee Phillips has a conversation with Dr. Scott Dawson of UC Davis about the unique biology and challenges of studying the parasite Giardia lamblia. Read Dr. Dawson’s paper titled, “Harnessing the power of new genetic tools to illuminate Giardia biology and pathogenesis,” published in the April 2024 issue of GENETICS: https://doi.org/10.1093/genetics/iyae038.  Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

  • 11. How C. elegans protect its genome with piRNAs – A conversation with Dr. Jordan Brown

    27:23||Season 1, Ep. 11
    In this episode of Genetics in Your World, Early Career Scientist Multimedia Subcommittee member Tammy Lee has a conversation with Dr. Jordan Brown, a recent alumnus from the University of Chicago, about factors involved in gene silencing mediated by small RNAs. Read Dr. Brown’s paper titled, “Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing,” published in the August 2023 issue of GENETICS: ​​https://doi.org/10.1093/genetics/iyad095.  Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

  • 9. Ep. 9. Interrogating Fungal Pathogens & Inspired Leadership – A Discussion With Dr. Christina Cuomo

    35:07||Season 1, Ep. 9
    In this episode of Genetics in Your World, Sarah Renee Phillips interviews Dr. Christina Cuomo about her paper "Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam," published in the August 2023 issue of GENETICS. Dr. Cuomo elaborates on the diversity and evolution of a deadly fungal pathogen from southeast Asia and how she and her colleagues used a combination of population genomics and genome-wide association studies to identify evolutionary pattern and process as well as genes influencing patient experiences and health outcomes.

  • 8. Ep. 8. Unexpected Discoveries in Drosophila – A Conversation with Dr. Hunter Hill

    25:38||Season 1, Ep. 8
    In this installment of Genetics in Your World, we talk to Dr. Hunter Hill of the University of Montana. He discusses unexpected recent discoveries made while completing his PhD with Dr. Kent Golic at the University of Utah, surrounding new and exciting data about the breakage pattern of chromosomes in Drosophila. He provides advice for others when encountering obstacles during their graduate studies. Check out the paper, "Dicentric chromosome breakage in Drosophila melanogaster is influenced by pericentric heterochromatic and occurs in non-conserved hotspots," published in the June 2023 issue of GENETICS.

  • 7. Ep. 7. HIMs and ZIMs in C. elegans meiosis – A Conversation with Ting Gong

    18:08||Season 1, Ep. 7
    In this installment of Genetics in Your World, we talk to Ting Gong of UC Davis. She discusses the surprising results she found when disrupting meiotic chromosome segregation in C. elegans.

  • 6. Ep. 6. "Science is like a detective story!" – A Conversation with Dr. Francis Collins

    31:33||Season 1, Ep. 6
    Join us for a special episode of Genetics in Your World where we interview previous National Institutes of Health (NIH) director Dr. Francis Collins. In this episode, Francis discusses his pathway into science, how he deals with failures in research, and his advice for future scientists.

  • 5. Ep. 5. Happy accidents in the lab – A Discussion with Dr. Thomas Merritt

    38:35||Season 1, Ep. 5
    “What do penicillin, saccharine, post-it notes, and x-ray machines have in common? They were all the outcome of happy accidents in the laboratory. Listen to Genetics in Your World: Episode 5 to find out how a bad day in the laboratory of Dr. Thomas Merritt turned treasure gold.”