Forum

Chief Editor Barbara Cheifet speaks with Drs. Michael Fischbach and Sarkis Mazmanian about recent work uncovering functional roles for our microbiomes and what is needed to bring microbiome therapies to the clinic. 

Jayme Locke and Megan Sykes discuss advances in xenotransplantation with Chief Editor Barbara Cheifet, including details of the recent transplants of pig heart and kidney into braindead patients, as well as the questions researchers and clinicians are asking next. 

Aviv Regev and Sarah Teichmann talk with Senior Editor Barbara Cheifet about the development and exciting recent progress of the Human Cell Atlas project.

Senior Editor Markus Elsner has a discussion with Ray Deshaies and Carolyn Bertozzi about PROTACs, small molecules that have the potential to treat previously-undruggable targets in clinical applications.

Ana Pombo and Jennifer Phillips-Cremins talk with senior editor Barbara Cheifet about how new methods to look at the 3D genome are providing insights into the links between genome structure and cellular function.

Kimberly Stegmaier and John Doench speak with senior editor Markus Elsner about the history and latest developments in the field of CRISPR screening.