eCysticFibrosis Review

Do cystic fibrosis lung impairment and the COVID-19 virus create the disastrous combination they would seem to make? What do the currently published data say about the clinical effects of the pandemic on people living with CF? How have the safety-mandated lockdowns and clinic closures affected CF care teams’ ability to effectively maintain their patients’ health? What information out there is proved, what’s speculation, and what is simply unknown?These questions are the focus of thiseCysticFibrosisReview Special COVID Editionissue.LisaSaimanMD, MPH,professor ofpediatrics atColumbia University Irving Medical Center,analyzes the current literature investigating these questions and then speaks directly with front-line clinicians about what they’re experiencing as they navigate adisrupted health care system.In addition to presenting her analysis of the data-driven evidence describing the effects of the COVID-19 virus on people with cystic fibrosis, Dr.Saimanalso spoke directly with front-line CF clinicians to learn about what they’ve been experiencing as they work to maintain effective patient care. Transcripts of these interviews can be accessed throughout the newsletter.Take ourpost-testto claim CME credits.

Do cystic fibrosis lung impairment and the COVID-19 virus create the disastrous combination they would seem to make? What do the currently published data say about the clinical effects of the pandemic on people living with CF? How have the safety-mandated lockdowns and clinic closures affected CF care teams’ ability to effectively maintain their patients’ health? What information out there is proved, what’s speculation, and what is simply unknown?These questions are the focus of this eCysticFibrosis Review Special COVID Edition issue.

Do cystic fibrosis lung impairment and the COVID-19 virus create the disastrous combination they would seem to make? What do the currently published data say about the clinical effects of the pandemic on people living with CF? How have the safety-mandated lockdowns and clinic closures affected CF care teams’ ability to effectively maintain their patients’ health? What information out there is proved, what’s speculation, and what is simply unknown?These questions are the focus of this eCysticFibrosis Review Special COVID Edition issue.

Do cystic fibrosis lung impairment and the COVID-19 virus create the disastrous combination they would seem to make? What do the currently published data say about the clinical effects of the pandemic on people living with CF? How have the safety-mandated lockdowns and clinic closures affected CF care teams’ ability to effectively maintain their patients’ health? What information out there is proved, what’s speculation, and what is simply unknown?These questions are the focus of this eCysticFibrosis Review Special COVID Edition issue.

Studies have shown that adolescent and young adult women with cystic fibrosis often turn to their CF care team for answersto their questionsabout their sexual and reproductive health. But how prepared areCFclinicians to initiate conversations? Do they have the most current data about pregnancy decisions for women taking CFTR modulators? When should modulator therapy be stopped? When is it safe to continue?In thiseCysticFibrosisReview podcast, Dr. TraciKazmerskifrom UPMC Children's Hospital of Pittsburgh and Dr. Natalie West fromJohns Hopkins Universitytake us into the clinic to address these important questions.To read a companion newsletterclick here.

Airway infections are a hallmark of cystic fibrosis, making antibiotic therapies a mainstay of CF treatment. While the fight against ABX resistance is ongoing, newer data are showing that commonly used dosing regimens mayhaveto be altered to account for the particular pharmacodynamics in people with CF. How should ABX dosing be altered, and what additional effect might CFTR modulation have on dosing decisions? That’s the topic Dr. Andrea Hahn, Assistant Professor of Pediatrics and an Infectious Disease Specialist at Children’s National Medical Center and George Washington University School of Medicine and Health Sciences, addresses in thiseCysticFibrosisReview podcast.Take our post-test to claim CME credits.To read a companion newsletterclick here.