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Cancer Research Matters

Microenvironments and early detection - 20 years of proteomics in cancer research

Season 1, Ep. 3

This episode features Sara Zanivan. Sara is a Professor at the Beatson Institute for Cancer where she uses a number proteomics approaches to explore the tumour microenvironment. Her lab also applies their proteomics expertise and capability to develop cancer early detection approaches. Specifically, she is interested in utilising mass-spectrometry to examine how large proteomic changes could be used in the clinic. 

          

She talks about how understanding the tumour microenvironment has developed over the past 20 years, how the techniques of proteomics have really freed researchers to ask the important questions and why we could even see mass-spec proteomics in the clinic.     


Further reading on mass-spectrometry and proteomics:

Journal paper:

https://www.nature.com/articles/nature01511

Article:

https://portlandpress.com/biochemist/article/42/5/64/226371/A-beginner-s-guide-to-mass-spectrometry-based

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