Dhru Purohit Podcast

1/23/2023

Psychedelics: Treating Addiction, Depression, and Anxiety with Dr. Roland Griffiths

Season 2, Ep. 175

This episode is brought to you by InsideTracker and Pendulum.

Psychedelics were the subject of serious medical research from the 1940s through the 1960s, when many scientists believed some of the mind-bending compounds held tremendous therapeutic promise for treating a number of conditions, including severe mental health problems and alcohol addiction. But by the mid-1960s, research into psychedelics was shut down, a policy that would last for decades.

After the blackout ended, the doctor we have on the podcast today was among the first to initiate a new series of studies on psilocybin—the psychoactive compound in “magic” mushrooms.

Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Roland Griffiths, a professor in the Department of Psychiatry and Neurosciences at Johns Hopkins University School of Medicine. Dr. Griffiths has conducted extensive research with sedative-hypnotics, caffeine, and novel mood-altering drugs. In 1999, he initiated a research program at Johns Hopkins investigating the effects of the classic hallucinogen psilocybin. The program includes studies of psilocybin-facilitated treatment of psychological distress in cancer patients and cigarette-smoking cessation as well as the compound’s effects in beginning and long-term meditators and religious leaders.

In this episode, Dhru and Dr. Griffiths discuss his research on psilocybin in the treatment of psychological distress in cancer patients and cigarette-smoking cessation. They discuss the connection between psilocybin, spirituality, and consciousness and their potential for treating conditions ranging from drug and alcohol dependence to depression and post-traumatic stress disorder.

In this episode, Dhru and Dr. Griffiths dive into:

-The connection between psychedelics, spirituality, and consciousness (3:30)

-The history of psychedelic research (12:32)

-The reintroduction of psychedelic research by Dr. Roland Griffiths and others (16:31)

-Why research participants rated their psychedelic experience as one of their most meaningful (20:57)

-What is happening in the brain when using psychedelics (27:39)

-How psychedelics can help us understand altered states of consciousness (33:13)

-The therapeutic benefits of psilocybin for the treatment of addiction (44:20)

-How a single dose of psilocybin substantially diminished depression and anxiety in cancer patients (48:56)

-The future of psychedelics (52:11)

-The downside and risks of psychedelics (1:00:18)

-Learn more about Dr. Roland Griffiths and his work (1:04:28)

For more on Dr. Roland Griffiths and his research on psychedelics, check out his website https://www.hopkinspsychedelic.org.

InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to https://www.insidetracker.com/DHRU to get your discount and try it out for yourself.

Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to https://www.Pendulumlife.com and use code DHRU20.

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3/23/2023

Two Crucial Things To Focus On If You Care About Longevity, Weight Loss And Metabolic Health With Dr. Don Layman

Season 2, Ep. 192

This episode is brought to you by BiOptimizers Magnesium Breakthrough, Mitopure, and BON CHARGE.Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Donald Layman, a pioneer in establishing optimal protein and amino-acid requirements for chronic disease prevention, performance, and longevity. Dhru and Dr. Layman discuss the importance of dietary protein for blood sugar control, building muscle mass, weight loss, and preventing age-related loss of lean tissue. Dr. Donald Layman is one of the world’s leading researchers on protein and amino-acid requirements for athletes, adult health, and chronic disease prevention. His research is focused on the impact of diet and exercise on the most troublesome chronic diseases today: obesity, diabetes, cardiovascular disease, and metabolic syndrome. With a highly respected academic career spanning over four decades, Dr. Layman has received numerous awards for his research publications in optimal protein intake, glycemic control, and weight loss. He has both a master’s degree in biochemistry and a doctorate in nutrition and biochemistry. In this episode, Dhru and Dr. Layman dive into:-Misconceptions around protein (3:03)-The downsides of not getting adequate dietary protein (11:18)-Protein, muscle synthesis, and longevity (13:08)-Dhru’s South Asian heritage and risk for cardiovascular disease (20:14)-Why dietary protein is important for women (32:55)-The history behind the RDA for protein intake (36:11)-Fasting and protein intake to prevent muscle wasting (41:46)-Early epidemiological research and the deprioritization of animal protein (51:29)-Leucine: the rate-limiting amino acid in muscle protein synthesis (1:06:46)-Resistance training and protein requirements for weight loss (1:17:32)-The pros of industry-funded nutrition research (1:31:54)-mTOR, protein intake, muscle synthesis, and cancer risk (1:40:50)-Building your diet around protein intake (1:54:55)Also mentioned in this episode:-Dr. Layman’s research publicationsFor more on Dr. Donald Layman, follow him on Twitter @donlayman or through his website, https://www.metabolictransformation.com.Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off plus a special gift with purchase, so just head over to magbreakthrough.com/dhru with code DHRU10.Mitopure is the first and only clinically tested, pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Head on over to timelinenutrition.com/dhru for 10% off.BON CHARGE is a holistic wellness brand with a HUGE range of evidence-based products to optimize your life. Right now, my community can go to boncharge.com/DHRU and use coupon code DHRU to save 15%.

3/20/2023

Getting To The Root Of Adrenal Dysfunction with Izabella Wentz

Season 2, Ep. 191

This episode is brought to you by InsideTracker and WHOOP. Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Izabella Wentz to discuss the common signs of adrenal fatigue and how to support adrenal function using diet, lifestyle, stress management, and targeted supplements for radical healing. Dr. Wentz shares her experience with Hashimoto’s thyroiditis and the personal protocol she used to reverse her symptoms and take back her health. Dr. Izabella Wentz is an internationally acclaimed thyroid specialist and a licensed clinical pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto’s thyroiditis in 2009. She is the author of three books on Hashimoto’s: Hashimoto’s Thyroiditis Lifestyle Interventions for Finding and Treating the Root Cause, Hashimoto’s Food Pharmacology, and the New York Times bestseller, Hashimoto’s Protocol. Her newest book, Adrenal Transformation Protocol: A 4-Week Plan to Release Stress Symptoms and Go from Surviving to Thriving, is set to release on April 18, 2023. In this episode, Dhru and Dr. Wentz dive into:-Top signs you might have adrenal dysfunction (1:25)-Long-term consequences of adrenal fatigue (6:22)-The HPA axis (13:09)-Why women are more prone to adrenal stress than men (15:27)-What happened to Izabella before she got sick (19:56)-Dr. Wentz’s personal protocol for supporting her adrenals (27:44)-Supplements for adrenal support (39:23)-Tests for adrenal dysfunction (47:14)-The root causes of adrenal issues (50:06)-Adaptogens for adrenal support (57:12)-Dietary approach for adrenal support (59:53)-Dr. Wentz’s adrenal transformation protocol (1:15:53)-Final thoughts and where to follow Izabella’s work (1:31:24)Also mentioned in this episode:-How to Release Self-Criticism and Find Fierce Self-Compassion with Dr. Kristen Neff (episode #123)-Adrenal Transformation Protocol is available for preorder here. -Sign up for Izabella’s Adrenal Healing Guide here.For more on Dr. Izabella Wentz, follow her on Instagram @izabellawentzpharmd, or through her website, https://www.thyroidpharmacist.com.InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to insidetracker.com/DHRU to get your discount and try it out for yourself.WHOOP is a personalized digital fitness tracker and health coaching platform that monitors your physiology 24/7 and provides personalized recommendations based on what your body needs. To get yours, go to join.whoop.com and get 15% off your membership with code DHRU15.

3/16/2023

The Insane Benefits of Cold and Hot Therapy on Mood, Energy, Metabolism and Brown Fat with Dr. Susanna Søberg

Season 2, Ep. 190

This episode is brought to you by InsideTracker, Pendulum, and Levels. Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Susanna Søberg to talk about her groundbreaking research on deliberate cold exposure and brown fat metabolism. Dhru and Dr. Søberg discuss the benefits of cold exposure for supporting mental and metabolic health as well as enhancing mood and energy in the short and long term. Dr. Susanna Søberg is one of the world’s leading researchers and experts in cold and heat therapy and functional breathing. She is also the founder of the Soeberg Institute. Dr. Søberg obtained her PhD in metabolism at the University of Copenhagen. Dr. Søberg is the author of the international bestseller Winter Swimming, which has been translated into 13 languages. Her new book, Thermalist, is available in Danish and hopefully soon in English.In this episode, Dhru and Dr. Søberg dive into:-The short-term benefits of cold therapy (3:07)-How cold therapy boosts dopamine and norepinephrine levels for better mood and energy (6:14)-The long-term benefits of cold therapy (20:42)-The evolutionary history behind the benefits of cold exposure (23:59)-Brown fat’s history and purpose and how to activate it (46:15)-Cold exposure improves insulin sensitivity (58:18)-Dr. Søberg’s research watching winter swimmers in Denmark (1:10:26)-Psychological improvements for cold exposure (1:22:00)-Minimal viable dose for the benefits of cold exposure (1:37:00)-Cold showers and other means of cold exposure (1:39:14)-The research on heat exposure (1:57:21)-Future research on cold exposure (2:35:35)Also mentioned in this episode:-Winter Swimming-The Thermalist (in Danish)-The Soeberg Institute’s course catalog (use code TRYTHIS for 10% off)For more on Dr. Susanna Søberg, follow her on Instagram @susanna_soeberg, or through her website, https://www.soeberginstitute.com. InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to insidetracker.com/DHRU to get your discount and try it out yourself.Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code DHRU20.Levels is an app that pairs with continuous glucose monitors and sends real-time feedback straight to your phone. Right now, Levels is offering my listeners two free months of their Levels Membership. Head on over to levels.link/DHRU to learn more.