"So much mystery now finally seems on the brink of elucidation." – Karl Deisseroth was working on a paper, late into the night, and had just gone to bed when the call came from Stockholm breaking the news that he had been awarded the 2026 Nobel Prize in Physiology or Medicine. In this interview with the Nobel Prize's Adam Smith, recorded while the rest of the household slept, he reflects on the possibilities for unravelling the mysteries of the brain that optogenetics is opening up. He also discusses how his own work with patients with psychiatric disorders informs his appreciation of their basis in the broad sweep of evolution, and his hope that this greater insight will help people understand each other better.
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