What happens when a genetic test taken just for fun reveals a BRCA1 mutation?
In this episode of BRCA & Beyond, Margot Casino shares her hereditary cancer story, from IVF and preventive surgery to a breast cancer diagnosis at 31 and finding a new normal. Around the time Margot got her results, her aunt was battling ovarian cancer, and they discovered they shared the exact same mutation. For Margot, that moment became a line in the sand between life before and life after.
In this conversation, Margot shares how she and her husband chose IVF with preimplantation genetic testing (PGT-M) to build their family and not pass on the mutation. She walks us through what the process really involved and what she’d want anyone considering it to know.
While going through preventive surgeries, Margot found a lump and trusted that something felt different. At 31, with two young sons at home, she was diagnosed with stage 3C invasive ductal carcinoma. We talk about treatment, her double mastectomy and reconstruction, body image, letting go of control, helping her boys feel safe, and accepting help from the people who love her.
Margot also opens up about grief, living with the fear of recurrence, and finding a new normal after hearing the words no evidence of disease. Whether you’re a previvor, a survivor, or supporting someone you love, her story is a powerful reminder to listen to your body and hold on to hope.
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This podcast shares personal stories and experiences for informational and inspirational purposes only. It does not replace medical advice, diagnosis, or treatment. Always consult your own doctor or healthcare provider before making any medical decisions.
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