{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/67a15023f0aed667c52953d7/688cecd5c6d705dd3aaefc49?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Episode 2 - Constipation with Shelley Stepanuik","description":"<h1>References from Shelley:</h1><p>- UpToDate as referenced summer 2025</p><p>&nbsp;</p><p>- RxFiles 2023 edition</p><p>&nbsp;</p><p>- Bristol Stool Chart</p><p>&nbsp;</p><p>-&nbsp;<a href=\"http://probioticchart.ca/\" rel=\"noopener noreferrer\" target=\"_blank\">probioticchart.ca</a></p><p>&nbsp;</p><p>- Why you should be careful with psyllium husk fiber supplement.&nbsp;YouTube:&nbsp;</p><p><a href=\"https://youtu.be/mPHXldh4_H4?si=wtAMhpP2QDCxPlr6\" rel=\"noopener noreferrer\" target=\"_blank\">https://youtu.be/mPHXldh4_H4?si=wtAMhpP2QDCxPlr6</a></p><p>&nbsp;</p><p>- Cascara Sagrada withdrawal in USA&nbsp;<a href=\"https://www.fda.gov/about-fda/fda-history-exhibits/drug-therapeutics-regulation-us\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.fda.gov/about-fda/fda-history-exhibits/drug-therapeutics-regulation-us#</a></p><p>&nbsp;</p><p>- Phenothalein withdrawal from market</p><p><a href=\"https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/phenolphthalein\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/phenolphthalein#</a></p><p>&nbsp;</p><p>- Bisacodyl&nbsp;</p><p>Neurogastroenterol Motil. 2021 Mar 9;33(10):e14123. doi: 10.1111/nmo.14123</p><p>&nbsp;</p><p>Bisacodyl: A review of pharmacology and clinical evidence to guide use in clinical practice in patients with constipation</p><p>&nbsp;</p><p>Maura Corsetti 1,2,, Sabine Landes 3, Robert Lange 4</p><p>PMCID: PMC8596401 PMID: 33751780</p><p><a href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC8596401/\" rel=\"noopener noreferrer\" target=\"_blank\">https://pmc.ncbi.nlm.nih.gov/articles/PMC8596401/</a></p><p>&nbsp;</p><p>- Stimulant laxatives&nbsp;</p><p>&nbsp;</p><p>First published online June 16, 2024</p><p>Review article: do stimulant laxatives damage the gut? A critical analysis of current knowledge</p><p>Peter Whorwell&nbsp;<a href=\"https://orcid.org/0000-0002-5220-8474\" rel=\"noopener noreferrer\" target=\"_blank\">https://orcid.org/0000-0002-5220-8474</a>&nbsp;<a href=\"mailto:peter.whorwell@mft.nhs.uk\" rel=\"noopener noreferrer\" target=\"_blank\">peter.whorwell@mft.nhs.uk</a>, Robert Lange, and Carmelo Scarpignato&nbsp;</p><p>&nbsp;</p><p><a href=\"https://doi.org/10.1177/17562848241249664\" rel=\"noopener noreferrer\" target=\"_blank\">https://doi.org/10.1177/17562848241249664</a></p><p>&nbsp;</p><p>- Rhubarb&nbsp;</p><p><a href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC8321582/\" rel=\"noopener noreferrer\" target=\"_blank\">https://pmc.ncbi.nlm.nih.gov/articles/PMC8321582/#</a></p><p>&nbsp;</p><p>- Demulcents</p><p><a href=\"https://www.sciencedirect.com/topics/neuroscience/demulcent\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.sciencedirect.com/topics/neuroscience/demulcent#</a></p><p><img src=\"data:image/gif;base64,R0lGODdhAQABAJEAAAAAAP///wAAAAAAACH5BAkAAAIALAAAAAABAAEAAAICVAEAOw==\"></p><p>&nbsp;</p><h1>References from Kim:</h1><p>Lexicomp drug information for: podophyllum, wheat dextrin, phenolpthalein, polyethylene glycol 3350</p><p><a href=\"https://time.com/archive/6617019/medicine-cut-out-the-liver/\" rel=\"noopener noreferrer\" target=\"_blank\">https://time.com/archive/6617019/medicine-cut-out-the-liver/</a></p><ul><li><strong>Pharmacology, toxicology, clinical efficacy, and adverse effects of calcium polycarbophil, an enteral hydrosorptive agent. </strong>PMID:&nbsp;6765389</li></ul><p><br></p>","author_name":"kimberley Kallio"}