In this in-depth conversation, Dr. Aubrey de Grey discusses his Robust Mouse Rejuvenation (RMR) studies at the LEV Foundation and why he believes we're close to achieving the crucial RMR milestone within just three years - a breakthrough that could transform aging research forever.
You'll also hear about:
His predictions for reaching Longevity Escape Velocity by the late 2030s
What he would change about Bryan Johnson's longevity algorithm
How reaching RMR could trigger a global \"war on aging\"
Why AI won't solve aging without proper experimental data
How Demis Hassabis is the smartest person Aubrey's ever met
His involvement in designing the XPRIZE Healthspan competition
His rebuttal to Mark Hamalainen's \"replacement strategy\" approach
The divide-and-conquer approach to aging and why it's superior
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-- CHAPTERS --
00:00 Introduction and Welcome
03:15 The Background to LEV Foundation and the Robust Mouse Rejuvenation Studies
12:05 The Robust Mouse Rejuvenation Studies
18:10 Latest Results from the Mouse Rejuvenation Experiments
25:42 Reaching RMR soon and LEV in 12-15 years
33:47 Healthspanners in public - lifespanners in private?
37:03 The Replacement Strategy Debate with Mark Hamalainen
45:40 The Very, Very Difficult Challenge of Gradually Replacing the Brain
54:46 Advanced bioengineering
57:34 The Debate with Peter Fedichev
01:11:57 Understanding Aging from an Evolutionary Perspective
01:17:05 Artificial Intelligence and Longevity Research
01:26:42 Is believing in AI hopium?
1:28:27 Aubrey’s Involvement in the XPRIZE Healthspan Competition
1:38:56 Special Economic Zones and Regulatory Challenges
1:47:27 What Aubrey would do with Bryan Johnson’s algorithm
1:50:49 What Excites Aubrey Most About the Future
1:51:57 Book Recommendations and Closing Thoughts
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