{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/65736d39d32e730012c98919/69320ae6a63c6eaa591a90c9?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Lung Organoids, Autism and Sarcopenia Insights in Mice, and a Bidding War Ends","description":"<p>Stories on lung organoids and autism were some of the most read this week. We kicked things off by digging into recent breakthroughs in both areas including an automated method for manufacturing iPSC-derived lung organoids and how a combination of supplements reduced autism-linked behaviors in mice. Still on the topic of new research, we discussed how a protein in the extracellular matrix helps muscle stem cells repair aging muscles. In business news, the bidding war between Lundbeck and Alkermes over Avadel Pharmaceuticals has ended. We talk about the possible implications of Lundbeck’s decision to back out and next steps for Alkermes. Then we dive into Protego Biopharma’s recent fundraising round, and efforts to develop small-molecule pharmacological chaperones that modulate protein stability in disease. </p><p>&nbsp;</p><p>&nbsp;</p><p>Join <em>GEN</em> editors Corinna Singleman, PhD, Alex Philippidis, and Uduak Thomas for a discussion of the latest biotech and biopharma news.&nbsp;</p><p>&nbsp;</p><p>Listed below are links to the <em>GEN</em> stories referenced in this episode of <em>Touching Base</em>:&nbsp;</p><p>&nbsp;</p><p><a href=\"https://www.genengnews.com/topics/bioprocessing/lung-organoids-generated-in-bulk-using-stirred-bioreactor-technology/\" rel=\"noopener noreferrer\" target=\"_blank\">Lung Organoids Generated in Bulk Using Stirred Bioreactor Technology</a><em> </em></p><p><em>GEN</em>, December 1, 2025</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/translational-medicine/supplement-trio-reduces-behavioral-deficits-in-mouse-models-of-autism/\" rel=\"noopener noreferrer\" target=\"_blank\">Autism-Linked Behaviors in Mice Reduced by Nutrient Trio</a></p><p><em>GEN</em>, December 3, 2025</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/translational-medicine/muscle-stem-cells-bolstered-by-ecm-protein-tenascin-c\" rel=\"noopener noreferrer\" target=\"_blank\">Muscle Stem Cells Bolstered by ECM Protein Tenascin-C</a></p><p><em>GEN</em>, December 5, 2025</p><p>&nbsp;</p><p><a href=\"https://www.genengnews.com/topics/translational-medicine/protego-closes-130m-series-b-to-fund-pivotal-trial-of-al-amyloidosis-candidate/\" rel=\"noopener noreferrer\" target=\"_blank\">Protego Closes $130M Series B to Fund Pivotal Trial of AL Amyloidosis Candidate</a></p><p>By Alex Philippidis, <em>GEN Edge,</em> December 3, 2025</p><p><a href=\"https://www.genengnews.com/topics/translational-medicine/lundbeck-ends-bidding-war-for-avadel-after-alkermes-up-to-2-37b-offer/\" rel=\"noopener noreferrer\" target=\"_blank\">Lundbeck Ends Bidding War for Avadel, After Alkermes’ Up-to-$2.37B Offer</a></p><p>By Alex Philippidis, <em>GEN Edge,</em> December 1, 2025</p><p><a href=\"https://www.genengnews.com/category/multimedia/podcasts/touching-base/\" rel=\"noopener noreferrer\" target=\"_blank\">Touching Base Podcast</a>&nbsp;</p><p>Hosted by Corinna Singleman, PhD&nbsp;</p><p>&nbsp;</p><p><a href=\"https://www.insideprecisionmedicine.com/category/multimedia/podcasts/\" rel=\"noopener noreferrer\" target=\"_blank\">Behind the Breakthroughs</a>&nbsp;</p><p>Hosted by Jonathan D. Grinstein, PhD&nbsp;</p>","author_name":"Genetic Engineering & Biotechnology News (GEN)"}