{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/65736d39d32e730012c98919/68fb8759834eaefbcedf3211?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Artificial Intelligence in the Emerald City and Targeting Colon Cancer Stem Cells ","description":"<p>We are gearing up for our annual AI in Drug Discovery summit in a few days. So, for this episode, we focused on some recent AI news coverage. First, <em>GEN</em> senior editor Fay Lin, PhD, visited Seattle recently for some AI-focused meetings. She discusses her experiences in the Emerald City including an exclusive in-person interview with Nobel laureate, David Baker, PhD, on what’s real and what’s hype when it comes to using AI to design proteins <em>de novo</em>.  Then we discuss new research from University of California, San Diego, that used machine learning to identify networks of genes that could be targeted to reprogram cancer stem cells. We also go over some early studies that point to a possible drug candidate for colon cancer.  &nbsp;</p><p> &nbsp;</p><p>Join <em>GEN</em> editors Corinna Singleman, PhD, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news. &nbsp;</p><p>&nbsp;</p><p>Listed below are links to the <em>GEN</em> stories referenced in this episode of <em>Touching Base</em>: &nbsp;</p><p> &nbsp;</p><p><a href=\"https://www.genengnews.com/news/brunkow-ramsdell-sakaguchi-win-nobel-prize-in-physiology-or-medicine-for-peripheral-immune-tolerance/\" rel=\"noopener noreferrer\" target=\"_blank\">Brunkow, Ramsdell, Sakaguchi Win Nobel Prize in Physiology or Medicine for Peripheral Immune Tolerance</a> &nbsp;</p><p>Uduak Thomas, <em>GEN</em>, October 6, 2025 &nbsp;</p><p> &nbsp;</p><p><a href=\"https://www.genengnews.com/topics/artificial-intelligence/ai-in-protein-design-hype-vs-reality-explained-by-david-baker/\" rel=\"noopener noreferrer\" target=\"_blank\">AI in Protein Design: Hype vs. Reality Explained by David Baker</a> &nbsp;</p><p>By Fay Lin, PhD, <em>GEN</em>, October 20, 2025 &nbsp;</p><p>  &nbsp;</p><p><a href=\"https://www.genengnews.com/topics/artificial-intelligence/nobel-anniversary-david-baker-keynotes-stem-fundraiser-by-arcs-foundation-seattle/\" rel=\"noopener noreferrer\" target=\"_blank\">Nobel Anniversary: David Baker Keynotes STEM Fundraiser by ARCS Foundation Seattle</a> &nbsp;</p><p>By Fay Lin, PhD, <em>GEN</em>, October 14, 2025 &nbsp;</p><p>   &nbsp;</p><p><a href=\"https://www.genengnews.com/topics/artificial-intelligence/ai-treatment-reprograms-and-triggers-cancer-stem-cells-to-self-destruct/\" rel=\"noopener noreferrer\" target=\"_blank\">AI Treatment Reprograms and Triggers Cancer Stem Cells to Self-Destruct</a> &nbsp;</p><p><em>GEN</em>, October 20, 2025 &nbsp;</p><p>   &nbsp;</p><p><a href=\"https://www.genengnews.com/multimedia/summits/the-state-of-ai-in-drug-discovery-2025/\" rel=\"noopener noreferrer\" target=\"_blank\">The State of AI in Drug Discovery Registration</a> &nbsp;</p><p> &nbsp;</p><p><a href=\"https://www.genengnews.com/category/multimedia/podcasts/touching-base/\" rel=\"noopener noreferrer\" target=\"_blank\">Touching Base Podcast</a> &nbsp;</p><p>Hosted by Corinna Singleman, PhD &nbsp;</p><p>&nbsp;</p><p><a href=\"https://www.insideprecisionmedicine.com/category/multimedia/podcasts/\" rel=\"noopener noreferrer\" target=\"_blank\">Behind the Breakthroughs</a> &nbsp;</p><p>Hosted by Jonathan D. Grinstein, PhD&nbsp;</p>","author_name":"Genetic Engineering & Biotechnology News (GEN)"}