{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/65736d39d32e730012c98919/67e6dabb903a636fc13ce615?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Dravet Gene Therapy Tested in Mice, Sarepta’s Setback, and AstraZeneca Updates","description":"<p>Gene therapies take center stage in this week’s episode. We discuss a potential gene replacement therapy for people with Dravet Syndrome that scientists have tested in mice with good results and highlight some recent progress from two editing companies. We also break down the recent news from Sarepta about the death of a patient after treatment with its gene therapy for Duchenne muscular dystrophy.&nbsp;In other stories, new data reveals a nonviral method for introducing transgenes into human primates and AstraZeneca steps up R&amp;D in China with new drug, vaccine, and healthcare partnerships in the billions of dollars.</p><p>Join <em>GEN</em> editors Corinna Singleman, PhD, Alex Philippidis, Julianna LeMieux, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news.&nbsp;</p><p><br></p><p>Listed below are links to the <em>GEN</em> stories referenced in this episode of <em>Touching Base</em></p><p><a href=\"https://www.genengnews.com/topics/genome-editing/gene-therapy-tested-in-mice-offers-new-hope-for-people-with-dravet-syndrome/\" rel=\"noopener noreferrer\" target=\"_blank\">Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome</a>&nbsp;</p><p>By Uduak Thomas, <em>GEN</em>, March 19, 2025&nbsp;</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/genome-editing/dmd-patient-dies-after-treatment-with-sarepta-gene-therapy/\" rel=\"noopener noreferrer\" target=\"_blank\">DMD Patient Dies After Treatment with Sarepta Gene Therapy</a></p><p>By Alex Philippidis, <em>GEN Edge</em>, March 18, 2025&nbsp;</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/genome-editing/piggybac-transposon-system-creates-transgenic-cynomolgus-monkeys/\" rel=\"noopener noreferrer\" target=\"_blank\">PiggyBac Transposon System Creates Transgenic Cynomolgus Monkeys</a></p><p>By Julianna LeMieux, PhD, <em>GEN</em>, March 26, 2025&nbsp;</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/genome-editing/from-tools-to-trials-editing-therapy-companies-pivot-to-development/\" rel=\"noopener noreferrer\" target=\"_blank\">From Tools to Trials: Editing Therapy Companies Pivot to Development</a></p><p>By Alex Philippidis, PhD, <em>GEN Edge</em>, March 20, 2025&nbsp;</p><p><br></p><p><a href=\"https://www.genengnews.com/topics/drug-discovery/astrazeneza-commits-up-to-11b-to-chinese-collaborations-beijing-rd-hub/\" rel=\"noopener noreferrer\" target=\"_blank\">AstraZeneca Commits up to $11B+ to Chinese Collaborations, Beijing R&amp;D Hub</a>&nbsp;</p><p>By Alex Philippidis, PhD, <em>GEN Edge</em>, March 21, 2025&nbsp;</p>","author_name":"Genetic Engineering & Biotechnology News (GEN)"}