Our guest today is Dr. Jonathan Bogan. Jonathan is a professor of Medicine and of Cell Biology at Yale University. He directs the Cell Biology Core of the Yale Diabetes Research Center and he is the attending physician in Internal Medicine and Endocrinology at Yale-New Haven Hospital. Jonathan's research centers on how insulin triggers cells to pull glucose out of the blood, and what happens when things go wrong in this process.
In this episode, Jonathan talks about how studying engineering as an undergrad evolved to a focus on biology, his discovery of the TUG protein and it's role in moving GLUT 4 transporters to the cell membrane and other aspects of physiology, surprising aspects of this discovery along with surprising connections between glucose transport and blood pressure, the thermic effect of food, and insulin resistance, and his advice to high school students interested in science.
Related resources:
Biorxiv preprint on diet and insulin resistance in mice
Essay on The Importance of Stupidity in Scientific Research by Martin A. Schwartz appearing in the Journal of Cell Science
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