{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/6490a6a7bf64170011e867ff/6adf6354677cf6f87d742a55?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Deucravacitinib in Psoriatic Disease","description":"<p>In this episode of <em>Inside GRAPPA</em>, Dr. Andre Lucas Ribeiro, Dr. Anna López Ferrer, and Professor Philip J. Mease explore the role of deucravacitinib, a selective TYK2 inhibitor, in the evolving treatment landscape of psoriatic disease.</p><p><br></p><p>Together, they examine the unmet needs in psoriasis and psoriatic arthritis, discuss the clinical evidence supporting deucravacitinib&#39;s efficacy and safety, and consider its potential place among existing treatment options. The conversation also highlights the importance of individualized treatment decisions, remaining evidence gaps, and future research opportunities.</p><p><br></p><h3><strong>Highlights</strong></h3><ul><li>Explore ongoing unmet needs in psoriatic arthritis and the importance of expanding oral treatment options.</li><li>Understand deucravacitinib&#39;s unique mechanism of action and how selective TYK2 inhibition differs from traditional JAK inhibitors.</li><li>Review key findings from the POETYK clinical trials, including efficacy in joint and skin manifestations.</li><li>Examine the safety and tolerability profile, including insights from long-term psoriasis data.</li><li>Discuss how deucravacitinib may fit into clinical practice and which patient characteristics may influence treatment selection.</li><li>Identify remaining research questions, including axial disease, difficult-to-treat PsA, and combination therapies.</li><li>Look ahead to ongoing studies and future opportunities to advance personalized treatment in psoriatic disease.</li></ul><h3><strong>Connect</strong></h3><p>Stay up to date with the latest psoriatic disease research, GRAPPA initiatives, and future episodes of <em>Inside GRAPPA</em> at<a href=\"https://www.grappanetwork.org\" rel=\"noopener noreferrer\" target=\"_blank\"> </a><u><a href=\"https://www.grappanetwork.org\" rel=\"noopener noreferrer\" target=\"_blank\">grappanetwork.org</a></u>.</p>","author_name":"GRAPPA Network"}