{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/631854ec30768d00133f2fe2/639813547e04bb00115f5b6d?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"JAKi and the brave new world of hair loss  ","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/631854ec30768d00133f2fe2/1670910774348-f28bad607b97955d2cc87a7ae6d8f807.jpeg?height=200","description":"<p>Patients with covid-related hair loss are benefiting from rheumatologists and dermatologists working together on its treatment, says Irish dermatologist Dr Dmitri Wall.</p><p>In June year, the JAK inhibitor baricitinib <a href=\"https://rheuma.com.au/game-changer-on-horizon-for-alopecia-areata/22377?utm_source=website&amp;utm_medium=listings-search&amp;utm_campaign=hair%20loss%22%20HYPERLINK%20%22https://rheuma.com.au/game-changer-on-horizon-for-alopecia-areata/22377\" rel=\"noopener noreferrer\" target=\"_blank\">won US FDA approval for patients with severe alopecia areata.</a>and is now being used for hair loss more broadly.&nbsp;</p><p>In this podcast episode, Dr Wall talks about the discussions he’s been having with rheumatologists when treating patients with severe hair loss associated with <a href=\"https://rheuma.com.au/could-rheumatology-hold-the-key-to-long-covid/21969\" rel=\"noopener noreferrer\" target=\"_blank\">long covid</a>.&nbsp;&nbsp;</p><p>“I have a number of patients back in Ireland who are seeing me and they're also seeing a rheumatologist. There's back and forth communication between me and the rheumatologists saying ‘Look, maybe we can alter the dose in this way to best cover both’,” he said.&nbsp;</p><p>Dr Wall said that for patients who have a more rapid trajectory and more extensive disease, one of the big, currentdiscussions \\is the use of JAK inhibitors. .&nbsp;</p><p>“It’s making a huge difference to patients with more severe or more progressive alopecia areata,” he said&nbsp;</p><p>Dr Wall also talks about his <a href=\"https://academic.oup.com/bjd/advance-article/doi/10.1093/bjd/ljac103/6847255\" rel=\"noopener noreferrer\" target=\"_blank\">recently published paper</a>&nbsp;which includes a case report on a patient with Crohn’s disease and severe hair loss. Dr Wall encouraged the patient to speak with his gastroenterologist about looking for clinical trials where both conditions could possibly be treated.&nbsp;&nbsp;</p><p>“I didn't hear anything for a year but then I got an email that said, ‘I just want to thank you. I got on that clinical trial and all my hair grew back’. As it turned out, he was treated with&nbsp;filgotinib, which has never been described in the area of alopecia areata before,” Dr Wall said.&nbsp;</p><p>Dr Wall provides some research insights from the <a href=\"https://astar-register.org/\" rel=\"noopener noreferrer\" target=\"_blank\">UK–Irish Atopic eczema Systemic Therapy Registry (A-STAR)</a> and reveals what showed up as a result of covid.&nbsp;</p><p>“We had this really strange but interesting collection of data suggesting that while some of the immunosuppressants could&nbsp;be beneficial with covid, some of them may actually be more damaging. And that's what the registry started to define as giving people a degree of awareness of the circumstances, the patients where they should or shouldn't be prescribed,” he said.&nbsp;</p>","author_name":"Rheumatology Republic"}