{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/6311fe9bae5d13001250521f/691f8fc93962bb012e301183?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Derisking Biotech: Smarter Indications and Better Resource Stretching for Early Teams","description":"<p>Derisk you biotech assets with 3 key coniderations. </p><p>Learn from drug development expert Angelique Greco and medtech-biotech founders and investors with tangible examples that show how real de-risking plays out. </p><p><br></p><p>🔍 <strong>What You’ll Learn</strong></p><p> Drug discovery feels like a maze when you're early in your career, especially when you're trying to build a biotech path without wasting years or cash. This episode gives you a clear way to turn solid science into something fundable.</p><p>You’ll learn:</p><p> • Where to find real support, from incubators to honest VC advice</p><p> • Why early commercial input matters and how to fix your market slide</p><p> • How smart entry points like animal health or adjacent indications de-risk your program and boost your funding chances</p><p><br></p><p><strong>Action:</strong> Press play if you want 20 minutes that cut months of guesswork.</p><p><br></p><p>🧠 <strong>About the Guest</strong></p><p> This episode brings insights from ShanShan Wang (RoamTech AI), Anushi Rajapaksa (Misti), Maryam Parviz (SDIP Innovations), Mike Lamprecht (Tenmile), and Ben Wright (Mimetic MedTech Foundry) on how founders can derisk and resource their team.</p><p> Plus why you do not always need an indication at the start, with lessons from Dr Chris Burns, whose team discovered Momelotinib in Australia before its FDA approval.</p><p><br></p><p>📌 <strong>Episode Highlights</strong></p><p> 00:00 Why de-risking matters for early biotech founders</p><p> 00:20 Two angles: advice and smarter indication choices</p><p> 01:00 How drug discovery fits a STEM entrepreneur path</p><p> 01:40 Upskilling vs burning cash and time</p><p> 02:10 Three pillars: compass, investors, venture studios</p><p><strong>Roadmap &amp; Upskilling</strong></p><p> 03:00 The value of a commercialization roadmap</p><p> 03:45 Han Wang on first seeing the map</p><p> 04:30 Anushi Rajapaksa on IP, regulatory and evolving the plan</p><p> 06:00 Where to find training, Bridge program, NSW program</p><p> 07:00 Why programs matter for network and support</p><p> 08:00 Maryam Parviz on global doors opening</p><p> 09:30 What you cannot Google: real conversations</p><p> 10:30 How informal mentoring happens</p><p> 11:00 Using tech transfer offices even if you're external</p><p><strong>Investor Advice</strong></p><p> 12:00 Why VC advice matters before fundraising</p><p> 13:00 Mike Lamprecht on critical early experiments</p><p> 14:00 What a realistic market conversation looks like</p><p><strong>Bridging Your Gaps</strong></p><p> 15:00 When to stop upskilling and bring experts</p><p> 15:40 Ben Wright on scaling support instead of solo learning</p><p> 16:00 How investors view founders who learn on the job</p><p> 17:00 How venture studios derisk early biotech and medtech</p><p> 18:00 Why structure and clinical champions matter</p><p><strong>Success Exists</strong></p><p> 18:45 Momelotinib as a real success story</p><p> 19:10 When starting with the molecule works</p><p> 20:00 Dr Chris Burns: from discovery to 2023 approval</p><p><strong>Smarter Entry Points</strong></p><p> 22:00 Why some programs need a side door</p><p> 22:30 What to check before picking an entry point</p><p> 23:00 Ivermectin from livestock to humans</p><p> 24:30 Ketamine and S-ketamine into severe depression</p><p> 26:00 How new IP opened new paths</p><p> 26:40 The semaglutide pivot</p><p><strong>Final Takeaways</strong></p><p> 27:00 Do not do it alone</p><p> 27:15 Get advice early, including from VC</p><p> 27:30 Philanthropy can be a real path</p><p> 27:45 Be realistic and optimistic, success exists</p>","author_name":"Angelique Greco | Biotech & Health-Tech Expert | STEM Thought Leadership Coach"}