{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/62d20dbcffef490011c8df4b/6a49faaa04fac73b24602893?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"207. ASCO 2026 - Agents of the Future - Part 2","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/62d20dbcffef490011c8df4b/1783233048639-689204e5-7a3e-4537-8aa2-d22bebb2b192.jpeg?height=200","description":"<p>This week, Josh and Michael's ASCO 2026 coverage looks at \"Agents of the Future\", trials of intrigue, promise and potential beyond its status. This episode also sheds light on more orphan status cancers like head and neck cancer, basket cohort studies, resistant EGFR lung cancer, metastatic colorectal cancer and hepatocellular carcinoma.</p><p><br></p><p>One more episode left of this arc - The Plenary! Stay tuned.</p><p><br></p><p><strong>Studies Discussed in this Episode</strong></p><p>OrigAMI-4</p><p>WU-KONG28</p><p>A Phase 1/2 Study of JK06, a 5T4-Targeted Antibody Drug Conjugate (ADC), In Patients with Unresectable Locally Advanced or Metastatic Cancer</p><p>ESANOA</p><p>ROSETTA Lung-02</p><p>Ivonescimab + FOLFOX</p><p>HERIZON-CRC01</p><p>CIRCULATE</p><p>EMERALD-3</p><p>BLUESTAR</p><p>GLP-1 agonist in breast cancer (Palleschi et al)</p><p><br></p><p>For more episodes, resources and blog posts, visit <a href=\"https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com\" rel=\"noopener noreferrer\" target=\"_blank\">www.inquisitiveonc.com</a></p><p>Please find us on Twitter <a href=\"https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!\" rel=\"noopener noreferrer\" target=\"_blank\">@InquisitiveOnc!</a></p><p>If you want us to look at a specific trial or subject, email us at <a href=\"mailto:inquisitiveonc@gmail.com\" rel=\"noopener noreferrer\" target=\"_blank\">inquisitiveonc@gmail.com</a></p><p><br></p><p>Art courtesy of Taryn Silver</p><p>Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/</p><p><br></p><p>Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.</p><p><br></p><p>Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content.</p>","author_name":"Michael Fernando and Josh Hurwitz"}