{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/62d20dbcffef490011c8df4b/67958f03ae8b037c9147e47a?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"142. San Antonio Breast Cancer Symposium 2024 - Part 1","description":"<p>Welcome back to Oncology for the Inquisitive Mind, where we head back to late 2024 and cover some pivotal trials and ideas from the San Antonio Breast Cancer Conference 2024.</p><p><br></p><p>This episode broadly covers hormone receptor-positive breast cancer and looks at another CDK comparison (real-world data). While the idea is not new, the potential implications from well-gathered \"phase 4\" data is a curious discussion point. Other  topics include the ESR1 mutation and Imlunestrant, Patritumab Deruxtecan in hormone receptor-positive disease and the role of CTDNA in tumour burden and recurrence in early breast cancer</p><p><br></p><p><strong>Studies discussed in the episode:</strong></p><p><a href=\"https://www.targetedonc.com/view/patritumab-deruxtecan-with-without-letrozole-shows-comparable-efficacy-in-hr-her2--breast-cancer\" rel=\"noopener noreferrer\" target=\"_blank\">SOLTI-VALENTINE</a></p><p><a href=\"https://www.nejm.org/doi/10.1056/NEJMoa2410858?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" rel=\"noopener noreferrer\" target=\"_blank\">EMBER 3</a></p><p><a href=\"https://www.targetedonc.com/view/ctdna-detection-tied-to-tumor-burden-recurrence-in-hr-early-breast-cancer\" rel=\"noopener noreferrer\" target=\"_blank\">ctDNA in EBC</a></p><p><a href=\"https://pubmed.ncbi.nlm.nih.gov/39754979/\" rel=\"noopener noreferrer\" target=\"_blank\">CDK Comparison</a></p><p><br></p><p>For more episodes, resources and blog posts, visit <a href=\"https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com\" rel=\"noopener noreferrer\" target=\"_blank\">www.inquisitiveonc.com</a></p><p>Please find us on Twitter <a href=\"https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!\" rel=\"noopener noreferrer\" target=\"_blank\">@InquisitiveOnc!</a></p><p>If you want us to look at a specific trial or subject, email us at <a href=\"mailto:inquisitiveonc@gmail.com\" rel=\"noopener noreferrer\" target=\"_blank\">inquisitiveonc@gmail.com</a></p><p><br></p><p>Art courtesy of Taryn Silver</p><p>Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/</p><p><br></p><p>Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.</p><p><br></p><p>Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Our partners have no editorial rights or early previews, and they have access to the episode at the same time you do.</p><p><br></p>","author_name":"Michael Fernando and Josh Hurwitz"}