{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/62d20dbcffef490011c8df4b/653f0791fa790d0011011eb5?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"74. ESMO 2023 - Upper GI and Hepatobiliary Cancer","description":"<p>Next up on the ESMO 2023 rollercoaster is an episode that is likely to be the shortest in our series: upper gastrointestinal and hepatobiliary oncology. As always, this remains a very challenging subarea of medical oncology, both in the clinical and trial spheres. However, our esteemed colleagues at ESMO remain undaunted by this challenge, and thus several studies of interest bear discussing. Will any of these studies lead to massive upheavals for clinicians and patients alike? For that answer, you'll have to listen on.</p><p><br></p><p>Links to studies discussed in this episodes (subscription may be required):</p><ul><li>Tinengotinib in patients with advanced, fibroblast growth factor receptor (FGFR) inhibitor refractory/relapsed cholangiocarcinoma <a href=\"https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/638034\" rel=\"noopener noreferrer\" target=\"_blank\">https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/638034</a></li><li>GEMSTONE-303: Prespecified progression-free survival (PFS) and overall survival (OS) final analyses of a phase III study of sugemalimab plus chemotherapy vs placebo plus chemotherapy in treatment-naïve advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma <a href=\"https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/639003\" rel=\"noopener noreferrer\" target=\"_blank\">https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/639003</a></li><li>Nab-paclitaxel plus gemcitabine versus modified FOLFIRINOX or S-IROX in metastatic or recurrent pancreatic cancer (JCOG1611, GENERATE): A multicentred, randomized, open-label, three-arm, phase II/III trial <a href=\"https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/637982\" rel=\"noopener noreferrer\" target=\"_blank\">https://esmocongress.esmo.org/esmo/esmo2023/en-GB/presentation/637982</a></li></ul><p><br></p><p>For more episodes, resources and blog posts, visit <a href=\"https://open.acast.com/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com\" rel=\"noopener noreferrer\" target=\"_blank\"><strong>www.inquisitiveonc.com</strong></a></p><p>Please find us on Twitter @InquisitiveOnc!</p><p>If you want us to look at a specific trial or subject, email us at<strong> </strong><a href=\"mailto:inquisitiveonc@gmail.com\" rel=\"noopener noreferrer\" target=\"_blank\"><strong>inquisitiveonc@gmail.com</strong></a></p><p><br></p><p>Art courtesy of Taryn Silver</p><p>Music courtesy of Music Unlimited: https://pixabay.com/users/music_unlimited-27600023/</p><p><br></p><p><strong>Disclaimer:</strong> This podcast is for educational purposes only. If you are unwell, seek medical advice.</p>","author_name":"Michael Fernando and Josh Hurwitz"}