{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/62d20dbcffef490011c8df4b/647c283bc1e93b0011c44364?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"42. ASCO 2023 - Gastroesophageal, Pancreatic and Hepatobiliary update","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/62d20dbcffef490011c8df4b/1687473382460-3b20e8f58a527fd01bed4aa559726f13.jpeg?height=200","description":"<p>ASCO 23 (American Society of Clinical Oncology) Annual Meeting in Chicago showcased a plethora of cutting-edge trials and research. Upper gastrointestinal cancers such as gastric, pancreatic and hepatobiliary are usually relegated to the backstage, but this year, several exciting and potentially practice-changing studies (not without their limitations).</p><p><br></p><p>We explore a new PD-1Toripalimab in gastric and gastroesophageal cancer, liposomal irinotecan in NALIRIFOX versus gemcitabine/abraxane in metastatic pancreatic cancer, neoadjuvant FOLFIRINOX in pancreatic cancer and the new HER2 kid on the block zanidatamab, a bispecific monoclonal antibody.</p><p><br></p><p>Stay tuned for daily ASCO updates from the OFTIM team, Michael and Josh.</p><p><br></p><p><strong><u>Studies:</u></strong></p><p><strong>Toripalimab + SOX study:</strong> <a href=\"https://meetings.asco.org/abstracts-presentations/219777\" rel=\"noopener noreferrer\" target=\"_blank\">https://meetings.asco.org/abstracts-presentations/219777</a></p><p><strong>NAPOLI-3 study: </strong> <a href=\"https://meetings.asco.org/abstracts-presentations/222090\" rel=\"noopener noreferrer\" target=\"_blank\">https://meetings.asco.org/abstracts-presentations/222090</a></p><p><strong>NORPACT-1 study:</strong> <a href=\"https://meetings.asco.org/abstracts-presentations/219426\" rel=\"noopener noreferrer\" target=\"_blank\">https://meetings.asco.org/abstracts-presentations/219426</a></p><p><strong>HORIZON-BTC-01 study: </strong><a href=\"https://meetings.asco.org/abstracts-presentations/219904\" rel=\"noopener noreferrer\" target=\"_blank\">https://meetings.asco.org/abstracts-presentations/219904</a></p><p><br></p><p><strong><u>Special Mention (not included in the episode)</u></strong></p><p><strong>DIPLOMA Study: </strong><a href=\"https://meetings.asco.org/abstracts-presentations/218312\" rel=\"noopener noreferrer\" target=\"_blank\">https://meetings.asco.org/abstracts-presentations/218312</a></p><p><br></p><p><strong>Lauren Classification: </strong><a href=\"https://open.acast.com/shows/62d20dbcffef490011c8df4b/episodes\" rel=\"noopener noreferrer\" target=\"_blank\">https://open.acast.com/shows/62d20dbcffef490011c8df4b/episodes</a></p><p><br></p><p>Many thanks to Merck for supporting this episode. Merck provided virtual access to ASCO 2023 but did not review or approve any part of OftiM's coverage of ASCO.</p><p><br></p><p>For more episodes, resources and blog posts, visit <a href=\"https://open.acast.com/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com\" rel=\"noopener noreferrer\" target=\"_blank\"><strong>www.inquisitiveonc.com</strong></a></p><p>Find us on Twitter <strong>@InquisitiveOnc!</strong></p><p>If you want us to look at a specific trial or subject, email us at<strong> </strong><a href=\"mailto:inquisitiveonc@gmail.com\" rel=\"noopener noreferrer\" target=\"_blank\"><strong>inquisitiveonc@gmail.com</strong></a></p><p><br></p><p>Art courtesy of Taryn Silver</p><p>Music courtesy of Music Unlimited: https://pixabay.com/users/music_unlimited-27600023/</p><p><br></p><p><strong>Disclaimer:</strong> This podcast is for educational purposes only. If you are unwell, seek medical advice.</p>","author_name":"Michael Fernando and Josh Hurwitz"}