Dr. Datis Kharrazian explains short-chain fatty acids and the postbiotics your gut bacteria make from fiber. He covers how butyrate calms inflammation, repairs leaky gut, and supports immune tolerance, while acetate and propionate help with blood sugar, satiety, and GLP-1. He also discusses LPS and endotoxemia, why butyrate can help people with SIBO or dysbiosis, how to dose it, and where probiotics fit in.
Interviewed by Elaine Marshall.
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TIMESTAMPS:
00:00 Discussing butyrate supplements and dosage
05:13 Benefits of butyrate for gut health
07:17 Role of LPS in inflammation
10:48 Starting butyrate supplementation
13:53 Teaching seminars and butyrate insights
17:20 Flaws in microbiome research
22:12 Understanding gut health supplements
23:34 Understanding microbiome and diet diversity
27:16 Health advice disclaimer
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