{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/60b20104ffcfab00117e6199/683855836e5b65d787b0b8f2?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Fasting - how it works and what you need to know if you are considering it","description":"<p>Fasting is a hot but contentious topic.&nbsp;</p><p>It has been practised for thousands of years and is now&nbsp;</p><p>purported to be a way of tackling or preventing certain metabolic diseases.&nbsp;</p><p>In this episode I look at the pros, cons and mechanisms of fasting.&nbsp;</p><p><br></p><p>Links:&nbsp;</p><p><br></p><p>Historical perspectives of fasting:&nbsp;<a href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC8838777/\" rel=\"noopener noreferrer\" target=\"_blank\">https://pmc.ncbi.nlm.nih.gov/articles/PMC8838777/</a></p><p><br></p><p>Time restricted feeding in mice (Sachin Panda):&nbsp;<a href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC3491655/\" rel=\"noopener noreferrer\" target=\"_blank\">https://pmc.ncbi.nlm.nih.gov/articles/PMC3491655/</a></p><p><br></p><p>Further study (see first image for feeding habits): <a href=\"https://www.sciencedirect.com/science/article/pii/S1550413114004987\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.sciencedirect.com/science/article/pii/S1550413114004987</a></p><p><br></p><p>5:2 diet summary:&nbsp;<a href=\"https://www.healthline.com/nutrition/the-5-2-diet-guide\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.healthline.com/nutrition/the-5-2-diet-guide</a></p><p><br></p><p>Prolonged fasting:&nbsp;<a href=\"https://pubmed.ncbi.nlm.nih.gov/37377031/\" rel=\"noopener noreferrer\" target=\"_blank\">https://pubmed.ncbi.nlm.nih.gov/37377031/</a></p><p><br></p><p>Fasting and autophagy:&nbsp;<a href=\"https://my.clevelandclinic.org/health/articles/24058-autophagy\" rel=\"noopener noreferrer\" target=\"_blank\">https://my.clevelandclinic.org/health/articles/24058-autophagy</a></p><p><br></p><p>The flip side - analysis of a study that found a increased link to heart disease from fasting:&nbsp;<a href=\"https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/intermittent-fasting#\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/intermittent-fasting#</a></p>","author_name":"Dr Ayan Panja"}