{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/60b20104ffcfab00117e6199/668ea11138b27712162bd247?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"B12 deficiency - the truth about it and the latest NICE guidance behind this all-important public health issue","description":"<p>B12 deficiency affects up to 20% of people over the age of 60. It is often left undiagnosed but can present</p><p>in many ways.&nbsp;In this episode I look at the nuance involved in making the diagnosis and treating it appropriately</p><p>so that people do not come to harm.</p><p><br></p><p>NICE guidance:&nbsp;<a href=\"https://www.nice.org.uk/guidance/ng239\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.nice.org.uk/guidance/ng239</a></p><p><br></p><p>B vitamins:&nbsp;<a href=\"https://www.healthline.com/health/food-nutrition/vitamin-b-complex#What-is-vitamin-B-complex?\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.healthline.com/health/food-nutrition/vitamin-b-complex#What-is-vitamin-B-complex?</a></p><p><br></p><p>Dr Casimir Funk:&nbsp;<a href=\"https://www.newscientist.com/article/2418743-casimir-funk-the-scientist-who-gave-us-the-word-vitamin/\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.newscientist.com/article/2418743-casimir-funk-the-scientist-who-gave-us-the-word-vitamin/</a></p><p><br></p><p>Beri-beri (B1 deficiency):&nbsp;<a href=\"https://medlineplus.gov/ency/article/000339.htm\" rel=\"noopener noreferrer\" target=\"_blank\">https://medlineplus.gov/ency/article/000339.htm</a></p><p><br></p><p>Pernicious anaemia:&nbsp;<a href=\"https://www.healthline.com/health/pernicious-anemia\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.healthline.com/health/pernicious-anemia</a></p><p><br></p><p>B12 food sources:&nbsp;<a href=\"https://www.medicalnewstoday.com/articles/vitamin-b12-foods\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.medicalnewstoday.com/articles/vitamin-b12-foods</a></p><p><br></p><p>Drugs that affect B12:&nbsp;<a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054240/\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054240/</a></p><p><br></p><p>Thyroid eye disease: <a href=\"https://my.clevelandclinic.org/health/diseases/17558-thyroid-eye-disease\" rel=\"noopener noreferrer\" target=\"_blank\">https://my.clevelandclinic.org/health/diseases/17558-thyroid-eye-disease</a></p><p><br></p><p>MMA testing:&nbsp;<a href=\"https://labtestsonline.org.uk/tests/methylmalonic-acid\" rel=\"noopener noreferrer\" target=\"_blank\">https://labtestsonline.org.uk/tests/methylmalonic-acid</a></p><p><br></p><p>Active B12:&nbsp;<a href=\"https://www.nice.org.uk/advice/mib40/chapter/introduction\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.nice.org.uk/advice/mib40/chapter/introduction</a></p><p><br></p><p>A decent explanation of methylation and why not all types of B12 and folate are the same for all:&nbsp;<a href=\"https://drkellymccann.com/beginners-guide-to-methylation-and-b-vitamins/\" rel=\"noopener noreferrer\" target=\"_blank\">https://drkellymccann.com/beginners-guide-to-methylation-and-b-vitamins/</a></p><p><br></p><p>Caution with B12/folate fortified foods if you have a methylation issue as they can be in the wrong form:&nbsp;<a href=\"https://zoe.com/learn/fortified-foods#\" rel=\"noopener noreferrer\" target=\"_blank\">https://zoe.com/learn/fortified-foods#</a></p><p><br></p><p>Sublingual B12 vs oral vs infection: <a href=\"https://link.springer.com/article/10.1007/s11845-023-03602-4#:~:text=Network%20meta%2Danalysis%20showed%20that,to%20increase%20vitamin%20B12%20levels.\" rel=\"noopener noreferrer\" target=\"_blank\">https://link.springer.com/article/10.1007/s11845-023-03602-4#</a></p><p><br></p><p>THE HEALTH FIX - the best health book in the world?! <a href=\"https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326/ref=asc_df_1914239326/?tag=googshopuk-21&amp;linkCode=df0&amp;hvadid=697328971196&amp;hvpos=&amp;hvnetw=g&amp;hvrand=15085882223374761530&amp;hvpone=&amp;hvptwo=&amp;hvqmt=&amp;hvdev=c&amp;hvdvcmdl=&amp;hvlocint=&amp;hvlocphy=9046035&amp;hvtargid=pla-1945548506375&amp;psc=1&amp;mcid=ef41a46debbf3e19bbfe4b0aa508b529&amp;gad_source=1\" rel=\"noopener noreferrer\" target=\"_blank\">https://www.amazon.co.uk/Health-Fix-Dr-Ayan-Panja/dp/1914239326</a></p>","author_name":"Dr Ayan Panja"}