{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/6007ebf7f983a73284ec8ef0/65083245cb582e0011a86430?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Running rats and healing hearts","description":"<p>In 1998, a young Norwegian exercise physiologist found that a technique he had used to help Olympic athletes could help heart patients too. But his idea made doctors sweat. One famous cardiologist told him that if he used his technique in human heart attack patients, he \"would kill them.\"</p><p>Today's show looks at what happened when our researcher, Ulrik Wisløff, defied the experts — and built a career learning how high intensity interval training can help everyone from heart patients and ageing Baby Boomers, and possibly even Alzheimer's patients — but not in the way you might think!</p><p>Our guests on today's show are <a href=\"https://www.ntnu.edu/employees/ulrik.wisloff\" rel=\"noopener noreferrer\" target=\"_blank\">Ulrik Wisløff,</a> <a href=\"https://www.ntnu.edu/employees/dorthe.stensvold\" rel=\"noopener noreferrer\" target=\"_blank\">Dorthe Stensvold</a> and<a href=\"https://www.ntnu.edu/employees/atefe.r.tari\" rel=\"noopener noreferrer\" target=\"_blank\"> Atefe Tari.</a></p><p>Here's a <a href=\"https://www.ntnu.edu/documents/139226/1297048454/Rat_on_treadmill.jpg/\" rel=\"noopener noreferrer\" target=\"_blank\">link to a rat on a treadmill</a> photo.</p><p>Here's a list of some of the research mentioned in the podcast, with links:</p><ul><li>Wisløff U, Helgerud J, Kemi OJ, Ellingsen O. <a href=\"https://journals.physiology.org/doi/full/10.1152/ajpheart.2001.280.3.H1301\" rel=\"noopener noreferrer\" target=\"_blank\">Intensity-controlled treadmill running in rats: VO(2 max) and cardiac hypertrophy</a>. Am J Physiol Heart Circ Physiol. 2001 Mar;280(3):H1301-10.</li><li>Wisløff U, Støylen A, Loennechen JP, Bruvold M, Rognmo Ø, Haram PM, Tjønna AE, Helgerud J, Slørdahl SA, Lee SJ, Videm V, Bye A, Smith GL, Najjar SM, Ellingsen Ø, Skjaerpe T. S<a href=\"https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.106.675041\" rel=\"noopener noreferrer\" target=\"_blank\">uperior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study.</a> Circulation. 2007 Jun 19;115(24):3086-94. doi: 10.1161/CIRCULATIONAHA.106.675041. Epub 2007 Jun 4.</li><li>Øivind Rognmo,&nbsp;Trine Moholdt,&nbsp;Hilde Bakken,&nbsp;Torstein Hole,&nbsp;Per Mølstad,&nbsp;Nils Erling Myhr,&nbsp;Jostein Grimsmo&nbsp;and&nbsp;Ulrik Wisløff.<a href=\"https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.112.123117\" rel=\"noopener noreferrer\" target=\"_blank\"> Cardiovascular Risk of High- Versus Moderate-Intensity Aerobic Exercise in Coronary Heart Disease Patients<strong> </strong></a>Circulation. 2012;126:1436-1440. doi: 10.1161/CIRCULATIONAHA.112.123117</li><li>Stensvold&nbsp;D,&nbsp;Viken&nbsp;H,&nbsp;Steinshamn&nbsp;S L,&nbsp;Dalen&nbsp;H,&nbsp;Støylen&nbsp;A,&nbsp;Loennechen&nbsp;J P&nbsp;et al.<a href=\"https://www.bmj.com/content/371/bmj.m3485.long\" rel=\"noopener noreferrer\" target=\"_blank\">&nbsp;Effect of exercise training for five years on all cause mortality in older adults—the Generation 100 study: randomised controlled trial</a>&nbsp;<em>BMJ&nbsp;</em>2020;&nbsp;371&nbsp;:m3485&nbsp;</li><li>Tari AR, Nauman J, Zisko N, Skjellegrind HK, Bosnes I, Bergh S, Stensvold D, Selbæk G, Wisløff U.<a href=\"https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(19)30183-5/fulltext\" rel=\"noopener noreferrer\" target=\"_blank\"> Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study</a>. Lancet Public Health. 2019 Nov;4(11):e565-e574.</li><li>Tari AR, Berg HH, Videm V, Bråthen G, White LR, Røsbjørgen RN, Scheffler K, Dalen H, Holte E, Haberg AK, Selbaek G, Lydersen S, Duezel E, Bergh S, Logan-Halvorsrud KR, Sando SB, Wisløff U. <a href=\"https://bmjopen.bmj.com/content/12/9/e056964.long\" rel=\"noopener noreferrer\" target=\"_blank\">Safety and efficacy of plasma transfusion from exercise-trained donors in patients with early Alzheimer's disease: protocol for the ExPlas study.</a> BMJ Open. 2022 Sep 6;12(9):e056964.</li></ul><p><br></p>","author_name":"NTNU"}