{"version":"1.0","type":"rich","provider_name":"Acast","provider_url":"https://acast.com","height":250,"width":700,"html":"<iframe src=\"https://embed.acast.com/$/5f2442bc6de29f32c4d05451/6166d6e82b747400135101f9?\" frameBorder=\"0\" width=\"700\" height=\"250\"></iframe>","title":"Producing challenging proteins in the golden age of protein engineering","thumbnail_width":200,"thumbnail_height":200,"thumbnail_url":"https://open-images.acast.com/shows/5f2442bc6de29f32c4d05451/1634133829981-1a8db81a3c83e8aaa33d069284068987.jpeg?height=200","description":"<p>In this episode, we roam the world of recombinant proteins and their production, discussing the challenges of their production, and recent evolutions in protein engineering that have brought the field into a golden era of innovation.</p><p><br></p><p>I'm joined by recombinant protein engineering expert Yuning Chen, R&amp;D Manager at Sino Biological, who discusses the key applications of recombinant proteins, the aspects of certain products that make them difficult to produce and how these difficulties can be overcome.&nbsp;Yuning also reveals how the manipulation of antibodies has been essential to multiple aspects of our response to the COVID-19 pandemic.</p><p><br></p><p>After a review of the recent evolutions in protein engineering, from cell-free systems to automation, Yuning describes his vision for the future of the field and reveals his support for the Terminator-style uprising that he believes could revolutionize it.</p><p><br></p><h2>Contents</h2><ul><li>The production of recombinant proteins: 00:48-02:11</li><li>The key applications of recombinant proteins: 02:11-03:27</li><li>What makes some proteins difficult to produce? 03:27-04:41</li><li>Overcoming these challenges:&nbsp;04:40-5:40</li><li>Manipulating antibodies to take part in multiple aspects of pandemic response: 05:40-08:00</li><li>The most exciting applications of recombinant proteins: 08:00-09:50</li><li>Developments in high throughput and automated protein engineering: 09:50-11:00</li><li>Cell-free protein engineering: 11:00-12:40</li><li>The benefits of cell-free systems: 12:40-13:40</li><li>What is next for recombinant protein production? 13:40-16:15</li><li>The dream of automation for the recombinant protein production: 16:15-18:50&nbsp;</li></ul>","author_name":"BioTechniques"}