During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the MPN Hub was pleased to speak with Jean-Jacques Kiladjian, Université Paris Cité, Paris, FR. We asked, What are the key findings from the 12-month primary endpoint analysis of the ROP-ET phase III study?
In this interview, Kiladjian first provided an overview of the phase III ROP-ET (NCT06514807) study design and key patient eligibility criteria. He then discussed the primary endpoint results, highlighting that the ROP-ET study met the primary endpoint – a composite durable hematologic and clinical response after 12 months. Finally, Kiladjian explored the safety profile of ropeginterferon alfa-2b observed in the study.
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